Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rajendran C. Gopalan"'
Autor:
Hassan Raza Ali Mazhar, K.H. Assi, Yuosef. Al ayoub, Rajendran C. Gopalan, Ghadeer Almousawi, B Alzouebi, Asma Buzgeia
Publikováno v:
Journal of Pharmaceutical Sciences. 111:395-402
In vitro dissolution testing as a form of quality control has become a necessity in the pharmaceutical industry. As such, the need to establish a method that investigates the in vitro dissolution profile of inhaled products should be taken into accou
Autor:
Lisa Newton, Mohammad Isreb, Mojgan Najafzadeh, Diana Anderson, Shabana Akhtar, Rajendran C. Gopalan
Publikováno v:
Archives of Toxicology
Evading apoptosis and chemo-resistance are considered as very important factors which help tumour progression and metastasis. Hence, to overcome chemo-resistance, there is an urgent requirement for emergence of more effective treatment options. Myric
Autor:
Lisa Newton, Shabana Akhtar, Rajendran C. Gopalan, Mojgan Najafzadeh, Diana Anderson, Mohammad Isreb
Publikováno v:
Toxicology Letters. 327:33-40
The present study investigated the genoprotective and genotoxic effects of myricetin bulk (10 μM) and nano forms (20 μM) in the lymphocytes from pre-cancerous, monoclonal gammopathy of unknown significance (MGUS) patients and healthy individuals us
Autor:
Mohammad Isreb, Shabana Akhtar, Lisa Newton, Rajendran C. Gopalan, Mojgan Najafzadeh, Diana Anderson
Publikováno v:
Archives of Toxicology
2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) is a central dietary mutagen, produced when proteinaceous food is heated at very high temperatures potentially causing DNA strand breaks. This study investigates the protective potential of a we
Autor:
Lisa Newton, Mohammad Isreb, Rajendran C. Gopalan, Mojgan Najafzadeh, Diana Anderson, Shabana Akhtar
Publikováno v:
Archives of Toxicology
We investigated the protective role of myricetin bulk and nanoforms, against reactive oxygen species (ROS)-induced oxidative stress caused by hydrogen peroxide and tertiary-butyl hydro peroxide in lymphocytes in vitro from healthy individuals and tho
Autor:
Rajendran C. Gopalan, Mohammad Amin Mohammad, Anant Paradkar, Mojgan Najafzadeh, Diana Anderson, Yuosef. Al ayoub, K.H. Assi
Publikováno v:
International Journal of Pharmaceutics. 557:254-263
Extensive research has demonstrated the potential effectiveness of curcumin against various diseases, including asthma and cancers. However, few studies have used liquid-based vehicles in the preparation of curcumin formulations. Therefore, the curre
Autor:
Fanila Shahzad, Chioma Nganwuchu, Sayeeda Rahman, Mainul Haque, Talat Nasim, Rajendran C. Gopalan, Anwarul Azim Majumder, Khaled Habas
Publikováno v:
Expert Review of Anti-infective Therapy
Coronavirus disease 2019 (COVID-19) was first detected in China in December, 2019, and declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. The current management of COVID-19 is based generally on supportive therapy and tr
Autor:
Mohammad Isreb, Mojgan Najafzadeh, Diana Anderson, Charmaine Normington, Badie K. Jacob, Rajendran C. Gopalan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity which affects the inflammatory response. Inflammation is associated with increasing cancer incidence. Pre-clinical and clinical studies have shown that NSAID treatment could c
Autor:
Mojgan, Najafzadeh, Charmaine, Normington, Badie K, Jacob, Mohammad, Isreb, Rajendran C, Gopalan, Diana, Anderson
Publikováno v:
Frontiers in Molecular Biosciences
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX enzyme activity which affects the inflammatory response. Inflammation is associated with increasing cancer incidence. Pre-clinical and clinical studies have shown that NSAID treatment could c
Autor:
Justin B. Davies, Mojgan Najafzadeh, Adolf Baumgartner, Diana Anderson, Rajendran C. Gopalan, P. Dominic Reynolds, Andrew Wright
Publikováno v:
Mutagenesis. 27:351-357
To use lymphocytes as surrogate cells to investigate their in vitro sensitivities to ultraviolet (UV) treatment in different cancers and precancerous states by comparison with lymphocytes from healthy control individuals was the main aim of this rese