Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rajendra Pangeni"'
Autor:
Keqiang Zhang, Lu Yang, Jinhui Wang, Ting Sun, Yuming Guo, Rebecca Nelson, Tommy R. Tong, Rajendra Pangeni, Ravi Salgia, Dan J. Raz
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-17 (2019)
Abstract Background Loss of monoubiquitination of histone H2B (H2Bub1) was found to be associated with poor differentiation, cancer stemness, and enhanced malignancy of non-small cell lung cancer (NSCLC). Herein, we investigated the biological signif
Externí odkaz:
https://doaj.org/article/f3bcd9977f1744a0b17408d286aea0c0
Autor:
Keqiang Zhang, Jinhui Wang, Lu Yang, Yate-Ching Yuan, Tommy R. Tong, Jun Wu, Xinwei Yun, Melissa Bonner, Rajendra Pangeni, Zheng Liu, Tiger Yuchi, Jae Y. Kim, Dan J. Raz
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background Dysregulated histone methyltransferase G9a may represent a potential cancer therapeutic target. The roles of G9a in tumorigenesis and therapeutics are not well understood in non-small cell lung cancer (NSCLC). Here we investigated
Externí odkaz:
https://doaj.org/article/b193a91202ec4aaa9c3ced0236ca109d
Autor:
Iuliia Topchu, Rajendra Pangeni, Igor Bychkov, Petr Makhov, John Karanicolas, Jindan Yu, Erica Golemis, Jochen Lorch, Yanis Boumber
Publikováno v:
Cancer Research. 82:3718-3718
Histone modifications play important role in regulating the function and structure of chromatin. Abnormal histone methylation is often detected during tumor development and progression. NSD1, NSD2, and NSD3 are key histone methyltransferases (HMTs) t
Autor:
Namratha G. Sastry, Tianzhi Huang, Angel Alvarez, Rajendra Pangeni, Xiao Song, Xuechao Wan, John Kessler, Ichiro Nakano, Bo Hu, Shi-Yuan Cheng
Publikováno v:
Cancer Research. 79:3432-3432
Glioblastoma (GBM) is the most malignant brain cancer, with extremely poor prognosis in patients. GBM tumors are characterized by distinct molecular subtypes, known as proneural (PN), classical, and mesenchymal (MES). Inherited heterogeneity and aber