Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Rajendra N Damle"'
Autor:
Denise L. Cecil, Benjamin Curtis, Ekram Gad, Michael Gormley, Andrew E. Timms, Lauren Corulli, Rinke Bos, Rajendra N. Damle, Manuel A. Sepulveda, Mary L. Disis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Prostate cancer is one of the few malignancies that includes vaccination as a treatment modality. Elements of an effective cancer vaccine should include the ability to elicit a Type I T-cell response and target multiple antigenic proteins ex
Externí odkaz:
https://doaj.org/article/747694e3df3f4e66a2c860aa790fac69
Autor:
Carlo Calissano, Rajendra N. Damle, Sonia Marsilio, Xiao-Jie Yan, Sophia Yancopoulos, Gregory Hayes, Claire Emson, Elizabeth J. Murphy, Marc K. Hellerstein, Cristina Sison, Matthew S. Kaufman, Jonathan E. Kolitz, Steven L. Allen, Kanti R. Rai, Ivana Ivanovic, Igor M. Dozmorov, Sergio Roa, Matthew D. Scharff, Wentian Li, Nicholas Chiorazzi
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c3739f0c9598420c8799dd44901b0253
Autor:
Alessandra Cesano, Omar Perbellini, Erik Evensen, Charles C. Chu, Federica Cioffi, Jason Ptacek, Rajendra N. Damle, Roberto Chignola, James Cordeiro, Xiao-jie Yan, Rachael E. Hawtin, Ilaria Nichele, Jodi R. Ware, Chiara Cavallini, Ornella Lovato, Roberta Zanotti, Kanti R. Rai, Nicholas Chiorazzi, Giovanni Pizzolo, Maria T. Scupoli
Publikováno v:
Haematologica, Vol 98, Iss 4 (2013)
While many prognostic markers in B-cell chronic lymphocytic leukemia provide insight into the biology of the disease, few have been demonstrated to be useful in the daily management of patients. B-cell receptor signaling is a driving event in the pro
Externí odkaz:
https://doaj.org/article/c72e69a3200b4835a794efa0b3e6ddbc
Autor:
Preetesh Jain, Mohammad Javdan, Franziska K. Feger, Pui Yan Chiu, Cristina Sison, Rajendra N. Damle, Tawfiqul A. Bhuiya, Filiz Sen, Lynne V. Abruzzo, Jan A. Burger, Andreas Rosenwald, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Nicholas Chiorazzi, Barbara Sherry
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
Background The levels and clinical relevance of Th17 cells and other interleukin-17-producing cells have not been analyzed in chronic lymphocytic leukemia. The objective of this study was to quantify blood and tissue levels of Th17 and other interleu
Externí odkaz:
https://doaj.org/article/255a3ce5dc8c48988504c3494e9ec965
Autor:
Shefali Patel, Linda A. Snyder, Jenny Driscoll, Carol Manning, Volha Tryputsen, Rajendra N. Damle, Kanaka Tatikola, Rao N.V.S. Mamidi, Jared Bohrer, Kathryn Packman, Rebecca Hawkins, Christopher F. Stratton
Publikováno v:
Cancer Research. 80:4128-4128
Patients whose prostate tumors bear deleterious mutations in genes that cause DNA repair defects (DRD), such as breast cancer (BRCA)2, respond to inhibitors of poly (ADP-ribose) [PAR] polymerase (PARP)-1 and PARP-2. Several PARP inhibitors, including
Autor:
Michael Lill, Stephen J. Schuster, Andrew Spencer, Judith Trotman, Sriram Balasubramanian, Michael Schaffer, Wojciech Jurczak, Bruce D. Cheson, Jessica Vermeulen, Shean Sheng Wang, Sanjay Deshpande, Nathan Fowler, John Radford, Peter Martin, Gary J. Gartenberg, Rajendra N. Damle, Dolores Caballero, James P. Morton, Jing Zhou Hou, Ajay K. Gopal, Gilles Salles, Georg Hess, Abdulraheem Yacoub, Umberto Vitolo
Publikováno v:
Gopal, A K, Schuster, S J, Fowler, N H, Trotman, J, Hess, G, Hou, J-Z, Yacoub, A, Lill, M, Martin, P, Vitolo, U, Spencer, A, Radford, J, Jurczak, W, Morton, J, Caballero, D, Deshpande, S, Gartenberg, G J, Wang, S-S, Damle, R N, Schaffer, M, Balasubramanian, S, Vermeulen, J, Cheson, B D & Salles, G 2018, ' Ibrutinib as Treatment for Patients With Relapsed/Refractory Follicular Lymphoma: Results From the Open-Label, Multicenter, Phase II DAWN Study ', J Clin Oncol, vol. 36, pp. 2405-2412 . https://doi.org/10.1200/JCO.2017.76.8853
Purpose The Bruton's tyrosine kinase inhibitor ibrutinib has demonstrated clinical activity in B-cell malignancies. The DAWN study assessed the efficacy and safety of single-agent ibrutinib in chemoimmunotherapy relapsed/refractory follicular lymphom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34e9a97f7d6674b15d5fc3d1a198db6
https://ruj.uj.edu.pl/xmlui/handle/item/143539
https://ruj.uj.edu.pl/xmlui/handle/item/143539
Autor:
Sergey Gorlatov, Ana Garrido, Kanti R. Rai, Rajendra N. Damle, Carol Moreno, Rosa Bosch, Miquel Granell, Albert Esquirol, Silvana Saavedra, Jorge Sierra, Irene Garcia, Emili Montserrat, Eva Puy Vicente, Julio Delgado, Nicholas Chiorazzi, Laura Blanco, Marta Pratcorona, Josep F. Nomdedeu, Rodrigo Martino, Alba Mora, Sonia Jansa, Gerardo Ferrer
Publikováno v:
Leukemialymphoma. 58(11)
In normal B-cells, B-cell antigen receptor (BCR) signaling can be negatively regulated by the low-affinity receptor FcγRIIb (CD32b). To better understand the role of FcγRIIb in chronic lymphocytic leukemia (CLL), we correlated its expression on 155
Autor:
Natalie L. Fulton, Denis Smirnov, Anna Hughes, Jenny Driscoll, David Derosa, Dong Shen, Karl Calara-Nielsen, Jennifer Hosbach, Linda A. Snyder, Rebecca Hawkins, Gerald Chu, Georges Habineza Ndikuyeze, Rajendra N. Damle
Publikováno v:
Cancer Research. 79:2134-2134
Patients with metastatic prostate cancer may initially respond well to first- and second-generation androgen receptor (AR)-targeted therapies, but many will experience disease progression, indicating a need for alternative therapies. A subset of thes
Autor:
Jonathan E. Kolitz, Matthew D. Scharff, Patricia K. A. Mongini, Thomas MacCarthy, Lu Zhang, Kanti R. Rai, Rajendra N. Damle, Sergio Roa, Amanda R. Magli, Steven L. Allen, Piers E.M. Patten, Charles C. Chu, Emilia Albesiano, Xiao-Jie Yan, Dorothy Kim, Jacqueline C. Barrientos, Nicholas Chiorazzi
Publikováno v:
Blood. 120:4802-4811
Clonal evolution occurs during the course of chronic lymphocytic leukemia (CLL) and activation-induced deaminase (AID) could influence this process. However, this possibility has been questioned in CLL because the number of circulating AID mRNA+ cell
Autor:
Lu Zhang, Sebastien Didier, Saul Teichberg, Arjun Dhayalan, William J. Kennedy, Jonathan E. Kolitz, Rajendra N. Damle, Charles C. Chu, Amanda R. Magli, Briana M. Agagnina, Prasad Koduru, Gia Fraher, Xiao-Jie Yan, Steven L. Allen, Piers E.M. Patten, Kanti R. Rai, Nicholas Chiorazzi, Linda P. Johnson
Publikováno v:
Molecular Medicine. 17:1338-1348
An infectious etiology has been proposed for many human cancers, but rarely have specific agents been identified. One difficulty has been the need to propagate cancer cells in vitro to produce the infectious agent in detectable quantity. We hypothesi