Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rajendra Kumar Palakurthy"'
Autor:
Rajendra Kumar, Palakurthy, Singhal, Prabhat K., Subba Rao, Malireddi R.K., Mahalingam, Sundarasamy ‡
Publikováno v:
In Journal of Biological Chemistry 4 March 2005 280(9):8553-8563
Publikováno v:
Genes & Development. 27:2221-2226
We previously identified 28 cofactors through which a RAS oncoprotein directs transcriptional silencing of Fas and other tumor suppressor genes (TSGs). Here we performed RNAi-based epistasis experiments and found that RAS-directed silencing occurs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46361837dcb17407431b4bf61f16f385
https://doi.org/10.1101/gad.227413.113
https://doi.org/10.1101/gad.227413.113
Autor:
Ling Lin, Manas Kumar Santra, Michael R. Green, Narendra Wajapeyee, Stéphane Gobeil, Claude Gazin, Rajendra Kumar Palakurthy
Publikováno v:
Molecular Cell. 36(2):219-230
The RASSF1A tumor suppressor gene is epigenetically silenced in a variety of cancers. Here, we perform a genome-wide human shRNA screen and find that epigenetic silencing of RASSF1A requires the homeobox protein HOXB3. We show that HOXB3 binds to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21a70d527614fcb83967303e835a822