Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rajendra Kedlaya"'
Autor:
Xinjie Xu, Rajendra Kedlaya, Hitoshi Higuchi, Sakae Ikeda, Monica J Justice, Vijayasaradhi Setaluri, Akihiro Ikeda
Publikováno v:
PLoS Genetics, Vol 6, Iss 5, p e1000956 (2010)
Intracellular trafficking is critical for delivering molecules and organelles to their proper destinations to carry out normal cellular functions. Disruption of intracellular trafficking has been implicated in the pathogenesis of various neurodegener
Externí odkaz:
https://doaj.org/article/d1a9265ca97d42d9a4861fb22108929f
Autor:
Teresita Bellido, Xi He, Paul J. Niziolek, Matthew L. Warman, Alexander G. Robling, Minjie Zhang, Rajendra Kedlaya, Bryan T. MacDonald
Publikováno v:
Journal of Bone and Mineral Research. 30:1822-1830
Certain missense mutations affecting LRP5 cause high bone mass (HBM) in humans. Based on in vitro evidence, HBM LRP5 receptors are thought to exert their effects by providing resistance to binding/inhibition of secreted LRP5 inhibitors such as sclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::809d2886413364b206c9d6c25d957da1
https://doi.org/10.1002/jbmr.2514
https://doi.org/10.1002/jbmr.2514
Autor:
Kyung Shin Kang, Vidya Bettagere, Kyung Eun Lim, Alexander G. Robling, Rajendra Kedlaya, Paola Divieti-Pajevic, Jung Min Hong, Daniel J. Horan
Publikováno v:
Endocrinology. 157(8)
β-Catenin (βcat) is a major downstream signaling node in canonical Wingless-related integration site (Wnt) signaling pathway, and its activity is crucial for canonical Wnt signal transduction. Wnt signaling has recently been implicated in the osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ec82032eaf7206b4a0be78c4bafa06
https://pubmed.ncbi.nlm.nih.gov/27253995
https://pubmed.ncbi.nlm.nih.gov/27253995
Autor:
Sulochana Devi, Vijayasaradhi Setaluri, Rajendra Kedlaya, Tie Fu Liu, Gokul Kandala, Nityanand Maddodi
Publikováno v:
Archives of Biochemistry and Biophysics. 508:227-233
By virtue of the presence of multiple protein–protein interaction and signaling domains, PDZ proteins play important roles in assembling protein complexes that participate in diverse cell biological processes. GIPC is a versatile PDZ protein that b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe929a3d10e7ecf1077122dcb8a53ed
https://doi.org/10.1016/j.abb.2011.01.021
https://doi.org/10.1016/j.abb.2011.01.021
Autor:
Rajendra Kedlaya, Naghma Khan, Farrukh Afaq, Deeba N. Syed, Hasan Mukhtar, Sami Sarfaraz, Vijayasaradhi Setaluri
Publikováno v:
Toxicology and Applied Pharmacology. 231:52-60
The HGF/Met signaling pathway is deregulated in majority of cancers and is associated with poor prognosis in breast cancer. Delphinidin, present in pigmented fruits and vegetables possesses potent anti-oxidant, anti-inflammatory and anti-angiogenic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95fd5c491ee3cc6ff788d3bd4979574
https://doi.org/10.1016/j.taap.2008.03.023
https://doi.org/10.1016/j.taap.2008.03.023
Autor:
Tiyyagura Koti Reddy, Rajendra Kedlaya, Ganesh Chandra Jagetia, Venkatasubbaiah A. Venkatesha
Publikováno v:
Clinica Chimica Acta. 347:189-197
Background: Iron is essential for oxygen transport and a variety of cellular processes like respiration and DNA synthesis. It may become toxic when not handled carefully by cellular proteins and shielded from surrounding media. Naringin treatment may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3454c6e1a36ed17d5634c46e492541
https://doi.org/10.1016/j.cccn.2004.04.022
https://doi.org/10.1016/j.cccn.2004.04.022
Autor:
Chris Paszty, Shreya Veera, Christina Jacobsen, Rachel E. Moss, Matthew L. Warman, Margot E. Bowen, Rajendra Kedlaya, Daniel J. Horan, Ugur M. Ayturk, Alexander G. Robling
Publikováno v:
Science translational medicine. 5(211)
Osteoporosis pseudoglioma syndrome (OPPG) is a rare genetic disease that produces debilitating effects in the skeleton. OPPG is caused by mutations in LRP5, a WNT co-receptor that mediates osteoblast activity. WNT signaling through LRP5, and also thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac48ae8bcc49584c102c2a14c5414d9
https://pubmed.ncbi.nlm.nih.gov/24296680
https://pubmed.ncbi.nlm.nih.gov/24296680
Autor:
Charles H. Turner, Alexander G. Robling, Teresita Bellido, Shana N. Ellis, Rajendra Kedlaya, Joseph P. Bidwell, Paul Childress
Publikováno v:
Endocrinology. 152(8)
PTH is a potent calcium-regulating factor that has skeletal anabolic effects when administered intermittently or catabolic effects when maintained at consistently high levels. Bone cells express PTH receptors, but the cellular responses to PTH in bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d0b404a28820ba58510a0de6cd7463
https://pubmed.ncbi.nlm.nih.gov/21652726
https://pubmed.ncbi.nlm.nih.gov/21652726
Autor:
Kumar M.R. Bhat, Sulochana Devi, Rajendra Kedlaya, Héctor H. Valdivia, Vijayasaradhi Setaluri, Nityanand Maddodi, Craig Weber
Publikováno v:
American journal of physiology. Cell physiology. 297(3)
Transient receptor potential melastatin (TRPM) is a subfamily of ion channels that are involved in sensing taste, ambient temperature, low pH, osmolarity, and chemical ligands. Melastatin 1/TRPM1, the founding member, was originally identified as mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2922089056518eaedad53f67536ad6e9
https://pubmed.ncbi.nlm.nih.gov/19587221
https://pubmed.ncbi.nlm.nih.gov/19587221
Autor:
Rajendra Kedlaya, Akihiro Ikeda, Xinjie Xu, Vijayasaradhi Setaluri, Sakae Ikeda, Hitoshi Higuchi, Monica J. Justice
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 6, Iss 5, p e1000956 (2010)
PLoS Genetics, Vol 6, Iss 5, p e1000956 (2010)
Intracellular trafficking is critical for delivering molecules and organelles to their proper destinations to carry out normal cellular functions. Disruption of intracellular trafficking has been implicated in the pathogenesis of various neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183b57f71b73a9d59ac1b43ba9b14821
https://pubmed.ncbi.nlm.nih.gov/20502676
https://pubmed.ncbi.nlm.nih.gov/20502676