Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Rajendra K. Tangirala"'
Autor:
Tamer Sallam, Ayaka Ito, Xin Rong, Jason Kim, Caroline van Stijn, Brian T. Chamberlain, Michael E. Jung, Lily C. Chao, Marius Jones, Thomas Gilliland, XiaoHui Wu, Grace L. Su, Rajendra K. Tangirala, Peter Tontonoz, Cynthia Hong
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 6, Pp 1120-1130 (2014)
The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to athe
Externí odkaz:
https://doaj.org/article/afa01ecac86245dc937e46ebaf3d70ed
Autor:
Lily C. Chao, Erin Soto, Cynthia Hong, Ayaka Ito, Liming Pei, Ajay Chawla, Orla M. Conneely, Rajendra K. Tangirala, Ronald M. Evans, Peter Tontonoz
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 806-815 (2013)
The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously demonstrated that NR4A nuclear receptors are highly induced in macrophages in response to inflammator
Externí odkaz:
https://doaj.org/article/29b91d7455394aef8be275635f72a7f6
Autor:
Cynthia Hong, Michele N. Bradley, Xin Rong, Xuping Wang, Alan Wagner, Victor Grijalva, Lawrence W. Castellani, Jon Salazar, Susan Realegeno, Rima Boyadjian, Alan M. Fogelman, Brian J. Van Lenten, Srinivasa T. Reddy, Aldons J. Lusis, Rajendra K. Tangirala, Peter Tontonoz
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 6, Pp 1126-1133 (2012)
The liver X receptor (LXR) signaling pathway is an important modulator of atherosclerosis, but the relative importance of the two LXRs in atheroprotection is incompletely understood. We show here that LXRα, the dominant LXR isotype expressed in live
Externí odkaz:
https://doaj.org/article/ff30e527bbf84aa4bcabb5bb64d96c53
Autor:
David A. Bird, Rajendra K. Tangirala, Joachim Fruebis, Daniel Steinberg, Joseph L. Witztum, Wulf Palinski
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 5, Pp 1079-1090 (1998)
Probucol is a powerful inhibitor of atherosclerosis in a number of animal models. However, it is unknown whether this is due to the strong antioxidant protection of low density lipoprotein (LDL), to antioxidant effects in the artery wall, or to cellu
Externí odkaz:
https://doaj.org/article/0fb8d8e4b6734921914a79e7676b8e37
Publikováno v:
Journal of Food Processing and Preservation. 46
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86404 (2014)
Adiponectin (APN), an adipocytokine produced by adipose tissue, exerts pleiotropic actions regulating inflammation, metabolism and vascular homeostasis. APN levels are inversely correlated with obesity, type-2 diabetes, hypertension and cardiovascula
Externí odkaz:
https://doaj.org/article/8f49fcd4e3ab4e70a6ab38acce202197
Publikováno v:
The FASEB Journal. 29:636-649
Adiponectin (APN), a pleiotropic adipokine that exerts anti-inflammatory, antidiabetic, and antiatherogenic effects through its receptors (AdipoRs), AdipoR1 and AdipoR2, is an important therapeutic target. Factors regulating AdipoR expression in mono
Autor:
Orla M. Conneely, Rajendra K. Tangirala, Liming Pei, Ajay Chawla, Ayaka Ito, Ronald M. Evans, Lily C. Chao, Peter Tontonoz, Erin Soto, Cynthia Hong
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 806-815 (2013)
Journal of Lipid Research
Journal of Lipid Research
The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously demonstrated that NR4A nuclear receptors are highly induced in macrophages in response to inflammator
Autor:
Emina Vorkapic, Aldons J. Lusis, Jason K. Kim, Caroline M. W. van Stijn, Dick Wågsäter, Per Eriksson, Rajendra K. Tangirala
Publikováno v:
Scientific Reports
Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by aortic dilation and rupture leading to sudden death. Currently, no non-surgical treatments are available and novel therapeutic targets are needed to prevent AAA. We investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c8e32cd14137a23b4be8fde9b3541c
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132053
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-132053
Autor:
Alan M. Fogelman, Cynthia Hong, Srinivasa T. Reddy, Victor Grijalva, Alan C. Wagner, Susan Realegeno, Brian J. Van Lenten, Xin Rong, Lawrence W. Castellani, Rima Boyadjian, Peter Tontonoz, Michelle N. Bradley, Jon Salazar, Rajendra K. Tangirala, Xuping Wang, Aldons J. Lusis
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 6, Pp 1126-1133 (2012)
Journal of Lipid Research
Journal of Lipid Research
The liver X receptor (LXR) signaling pathway is an important modulator of atherosclerosis, but the relative importance of the two LXRs in atheroprotection is incompletely understood. We show here that LXRα, the dominant LXR isotype expressed in live