Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rajendra K. Palakurthy"'
Autor:
Karthikeyan Narasingapuram Arumugam, Jwala Nagaraj, DS Samiulla, Murali Ramachandra, Rajendra K. Palakurthy, Rajeev Goswami, Olli Törmäkangas, Anirudha Lakshminarasimhan, Narasimha Rao Krishnamurthy, Gerd Wohlfahrt, Anu Moilanen, Subhendu Mukherjee, Mahaboobi Jaleel, Anita R. Chacko
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5309-5314
Hepsin, a type II transmembrane serine protease, is upregulated in prostate cancer and known to be involved in the progression of metastasis. Here we report a structure-guided approach, which resulted in the discovery of 2-aryl/pyridin-2-yl-1H-indole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11309c3bb66ab52d9329fa0c0ba4c60
https://doi.org/10.1016/j.bmcl.2015.09.042
https://doi.org/10.1016/j.bmcl.2015.09.042
Autor:
Krishnaprasad Subbarao, Jwala Nagaraj, Rajendra K. Palakurthy, Ramesh Kumar Sistla, Hosahalli Subramanya, Murali Ramachandra, Chakshusmathi Ghadiyaram, Gerd Wohlfahrt, Narasimha Rao Krishnamurthy, Sreevalsam Gopinath, Anu Moilanen, Subhendu Mukherjee, Pekka Kallio, Tarja Ikonen, Rajeev Goswami, Leena Khare Satyam
Publikováno v:
Bioorganicmedicinal chemistry. 22(12)
Matriptase is a serine protease implicated in cancer invasion and metastasis. Expression of matriptase is frequently dysregulated in human cancers and matriptase has been reported to activate latent growth factors such as hepatocyte growth factor/sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c843e7bca7b826071bdbe7d7c83e42d
https://pubmed.ncbi.nlm.nih.gov/24794746
https://pubmed.ncbi.nlm.nih.gov/24794746