Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rajendra Boggavarapu"'
Autor:
Shu-hao Liou, Rajendra Boggavarapu, Noah R. Cohen, Yue Zhang, Ishwari Sharma, Lynn Zeheb, Nidhi Mukund Acharekar, Hillary D. Rodgers, Saadman Islam, Jared Pitts, Cesar Arze, Harish Swaminathan, Nathan Yozwiak, Tuyen Ong, Roger J. Hajjar, Yong Chang, Kurt A. Swanson, Simon Delagrave
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Anelloviruses are nonpathogenic viruses that comprise a major portion of the human virome. Despite being ubiquitous in the human population, anelloviruses (ANVs) remain poorly understood. Basic features of the virus, such as the identity of
Externí odkaz:
https://doaj.org/article/e9feceb20c5447e1933ccba332f71551
Autor:
Mirko Stauffer, Jean-Marc Jeckelmann, Hüseyin Ilgü, Zöhre Ucurum, Rajendra Boggavarapu, Dimitrios Fotiadis
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-10 (2022)
Understanding the molecular interactions between proton-dependent oligopeptide transporters and their inhibitors is key to drug and tool development, but high-resolution co-crystal structure data remains scarce. Here, the authors report the crystal s
Externí odkaz:
https://doaj.org/article/66a453ed865a4feeb9e84f5e9c5adfae
Autor:
Rajendra Boggavarapu, Jean-Marc Jeckelmann, Daniel Harder, Philipp Schneider, Zöhre Ucurum, Matthias Hediger, Dimitrios Fotiadis
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76427 (2013)
Expression and purification of human membrane proteins for structural studies represent a great challenge. This is because micro- to milligram amounts of pure isolated protein are required. To this aim, we successfully expressed the human vitamin C t
Externí odkaz:
https://doaj.org/article/3c8498e6d4944bac8632b5880c8bf416
Autor:
Marc J Bergeron, Rajendra Boggavarapu, Marcel Meury, Zöhre Ucurum, Luc Caron, Paul Isenring, Matthias A Hediger, Dimitrios Fotiadis
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21901 (2011)
Structural analyses of heterologously expressed mammalian membrane proteins remain a great challenge given that microgram to milligram amounts of correctly folded and highly purified proteins are required. Here, we present a novel method for the expr
Externí odkaz:
https://doaj.org/article/94e2e0151e5e4a228e9a0fa2bcf3d155
Autor:
Rajendra, Boggavarapu, Stephan, Hirschi, Daniel, Harder, Marcel, Meury, Zöhre, Ucurum, Marc J, Bergeron, Dimitrios, Fotiadis
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1432
This protocol describes the isolation of recombinant human and mammalian membrane proteins expressed in Xenopus laevis frog oocytes for structural studies. The cDNA-derived cRNA of the desired genes is injected into several hundreds of oocytes, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7037ddd3998a30ab6f05937f427c3407
https://pubmed.ncbi.nlm.nih.gov/27485339
https://pubmed.ncbi.nlm.nih.gov/27485339
Autor:
Stephan Hirschi, Marcel Meury, Rajendra Boggavarapu, Marc J. Bergeron, Zöhre Ucurum, Dimitrios Fotiadis, Daniel Harder
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936359
This protocol describes the isolation of recombinant human and mammalian membrane proteins expressed in Xenopus laevis frog oocytes for structural studies. The cDNA-derived cRNA of the desired genes is injected into several hundreds of oocytes, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8ce228f42dd9a23806ab1b982d3a5ca
https://doi.org/10.1007/978-1-4939-3637-3_14
https://doi.org/10.1007/978-1-4939-3637-3_14
Publikováno v:
BMC Biology
Boggavarapu, Venkata Ravi Naga Rajendr; Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2015). Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC biology, 13(58), p. 58. BioMed Central 10.1186/s12915-015-0167-8
Boggavarapu, Venkata Ravi Naga Rajendr; Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2015). Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC biology, 13(58), p. 58. BioMed Central 10.1186/s12915-015-0167-8
Background Peptide transporters are membrane proteins that mediate the cellular uptake of di- and tripeptides, and of peptidomimetic drugs such as β-lactam antibiotics, antiviral drugs and antineoplastic agents. In spite of their high physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e6fe0d57ad8d14ef7340e4924960f1
Autor:
Dimitrios Fotiadis, Hüseyin Ilgü, Jean-Marc Jeckelmann, María Salomé Gachet, Rajendra Boggavarapu, Zöhre Ucurum, Jürg Gertsch
Publikováno v:
Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gachet Otanez, Maria Salomé; Boggavarapu, Venkata Ravi Naga Rajendr; Ucurum Fotiadis, Zöhre; Gertsch, Jürg; Fotiadis, Dimitrios José (2014). Variation of the detergent-binding capacity and phospholipid content of membrane proteins when purified in different detergents. Biophysical journal, 106(8), pp. 1660-1670. Biophysical Society 10.1016/j.bpj.2014.02.024
Purified membrane proteins are ternary complexes consisting of protein, lipid, and detergent. Information about the amounts of detergent and endogenous phospholipid molecules bound to purified membrane proteins is largely lacking. In this systematic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fee5e9ccfec2a21c3c52b88124478f
https://europepmc.org/articles/PMC4008799/
https://europepmc.org/articles/PMC4008799/
Autor:
Dimitrios Fotiadis, Daniel Harder, Jean-Marc Jeckelmann, Marcel Meury, Zöhre Ucurum, Rajendra Boggavarapu
Publikováno v:
Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004
Biological chemistry
Biological chemistry
High-resolution microscopy techniques provide a plethora of information on biological structures from the cellular level down to the molecular level. In this review, we present the unique capabilities of transmission electron and atomic force microsc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3469955e14eb73ac43d833a2ac5dff
https://pubmed.ncbi.nlm.nih.gov/21194358
https://pubmed.ncbi.nlm.nih.gov/21194358
Expression, Purification and Low-Resolution Structure of Human Vitamin C Transporter SVCT1 (SLC23A1)
Autor:
Daniel Harder, Rajendra Boggavarapu, Jean-Marc Jeckelmann, Philipp Schneider, Dimitrios Fotiadis, Matthias A. Hediger, Zöhre Ucurum
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76427 (2013)
PLoS ONE
Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Harder, Daniel; Schneider, Philipp; Ucurum, Zöhre; Hediger, Matthias; Fotiadis, Dimitrios (2013). Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS ONE, 8(10), e76427. Public Library of Science 10.1371/journal.pone.0076427
PloS one
PLoS ONE
Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Harder, Daniel; Schneider, Philipp; Ucurum, Zöhre; Hediger, Matthias; Fotiadis, Dimitrios (2013). Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS ONE, 8(10), e76427. Public Library of Science 10.1371/journal.pone.0076427
PloS one
Expression and purification of human membrane proteins for structural studies represent a great challenge. This is because micro- to milligram amounts of pure isolated protein are required. To this aim, we successfully expressed the human vitamin C t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af605a6ba2c47a56c9a598490e11e2c8
https://doi.org/10.1371/journal.pone.0076427
https://doi.org/10.1371/journal.pone.0076427