Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rajeev M Mahimkar"'
Autor:
John R. Doedens, Beverly J Castner, Guixian Jin, Susan W. Sunnarborg, Roy A. Black, R. Cowling, Jennifer L. Slack, Richard S. Johnson, Keith Charrier, Ray Paxton, Duke Virca, David C. Lee, Lin Guo, Alison Wallace, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Biochemical Society Symposia. 70:39-52
Tumour necrosis factor α (TNFα)-converting enzyme (TACE/ADAM-17, where ADAM stands for a disintegrin and metalloproteinase) releases from the cell surface the extracellular domains of TNF and several other proteins. Previous studies have found that
Publikováno v:
Biochemical and biophysical research communications. 308(2)
Tumor necrosis factor-alpha converting enzyme (TACE/ADAM-17) is a metalloprotease disintegrin that cleaves a variety of membrane proteins, releasing ("shedding") their extracellular domains from cells. Most TACE-mediated shedding events occur at low
Autor:
Raymond J. Paxton, Lin Guo, Roy A. Black, Richard S. Johnson, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Molecularcellular proteomics : MCP. 1(1)
Proteolytic cleavage (shedding) of extracellular domains of many membrane proteins by metalloproteases is an important regulatory mechanism used by mammalian cells in response to environmental and physiological changes. Here we describe a proteomic s