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pro vyhledávání: '"Rajeev Goswami"'
Autor:
Rajeev Goswami
Publikováno v:
International Journal of Electric and Hybrid Vehicles. 14:354
Publikováno v:
International Journal of Electric and Hybrid Vehicles. 12:44
India, one of the fastest growing economies, has been a front-runner in fulfilling its commitments towards a cleaner Earth. In this pursuit, it intends to adopt electric vehicles (EVs) to the tune of 30% by 2030. Central and state governments of Indi
Autor:
Karthikeyan Narasingapuram Arumugam, Jwala Nagaraj, DS Samiulla, Murali Ramachandra, Rajendra K. Palakurthy, Rajeev Goswami, Olli Törmäkangas, Anirudha Lakshminarasimhan, Narasimha Rao Krishnamurthy, Gerd Wohlfahrt, Anu Moilanen, Subhendu Mukherjee, Mahaboobi Jaleel, Anita R. Chacko
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5309-5314
Hepsin, a type II transmembrane serine protease, is upregulated in prostate cancer and known to be involved in the progression of metastasis. Here we report a structure-guided approach, which resulted in the discovery of 2-aryl/pyridin-2-yl-1H-indole
Autor:
Rajeev Goswami, Subhendu Mukherjee, Gerd Wohlfahrt, Jwala Nagaraj, Krishnaprasad Subbarao, Chakshusmathi Ghadiyaram, Narasimha Rao Krishnamurthy, Leena Khare Satyam, Sreevalsam Gopinath, Hosahalli Subramanya, Murali Ramachandra
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:616-620
Matriptase is a cell-surface trypsin-like serine protease of epithelial origin, which cleaves and activates proteins including hepatocyte growth factor/scatter factor and proteases such as uPA, which are involved in the progression of various cancers
Publikováno v:
International Journal of Electric and Hybrid Vehicles. 11:59
Fast urbanisation and motorisation growth have resulted in degraded air quality and increased burden on most of the cities, globally. Cities utilise two-thirds of the global energy and account for about 70% of GHG emissions. Therefore, it is importan
Publikováno v:
International Journal of Electric and Hybrid Vehicles. 10:334
Worldwide, reducing vehicular emission is a cumbersome task to save our planet from climate change. The introduction of electric vehicles could be one of the approaches to reduce the emissions. In this paper, various factors of total cost of ownershi
Autor:
Krishnaprasad Subbarao, Jwala Nagaraj, Rajendra K. Palakurthy, Ramesh Kumar Sistla, Hosahalli Subramanya, Murali Ramachandra, Chakshusmathi Ghadiyaram, Gerd Wohlfahrt, Narasimha Rao Krishnamurthy, Sreevalsam Gopinath, Anu Moilanen, Subhendu Mukherjee, Pekka Kallio, Tarja Ikonen, Rajeev Goswami, Leena Khare Satyam
Publikováno v:
Bioorganicmedicinal chemistry. 22(12)
Matriptase is a serine protease implicated in cancer invasion and metastasis. Expression of matriptase is frequently dysregulated in human cancers and matriptase has been reported to activate latent growth factors such as hepatocyte growth factor/sca
Autor:
Jwala Nagaraj, Chakshusmathi Ghadiyaram, Anu Moilanen, Ramesh Kumar Sistla, Murali Ramachandra, Hosahalli Subramanya, Subhendu Mukherjee, Leena Khare Satyam, DS Samiulla, Rajeev Goswami, Beeram Ravi Chandra, Gerd Wohlfahrt
Matriptase belongs to trypsin-like serine proteases involved in matrix remodeling/degradation, growth regulation, survival, motility, and cell morphogenesis. Herein, we report a structure-based approach, which led to the discovery of sulfonamide and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307579e787f4faa4490227606014b2fa
https://europepmc.org/articles/PMC4027570/
https://europepmc.org/articles/PMC4027570/
Publikováno v:
ChemInform. 36
Autor:
Rajeev Goswami, Hanumantharao G. Raj, Sanjay Goel, Carl Erik Olsen, Jesper Wengel, Ramesh C. Rastogi, Virinder S. Parmar, Subhash C. Jain, Ekta Kohli
Publikováno v:
Raj, H G, Kohli, E, Goswami, R, Goel, S, Rastogi, R C, Jain, S C, Wengel, J, Olsen, C E & Parmar, V S 2001, ' Mechanism of biochemical action of substituted benzopyran-2-ones : Part 8: Acetoxycoumarin: Protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom ', Bioorganic & Medicinal Chemistry, vol. 9, no. 5, pp. 1085-1089 . https://doi.org/10.1016/S0968-0896(00)00328-X
Our earlier work established a convenient assay procedure for acetoxycoumarin (AC): protein transacetylase (TA) by indirectly quantifying the activity of glutathione (GSH)-S-transferase (GST), the extent of inhibition of GST under the conditions of t