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pro vyhledávání: '"Rajee Hari"'
Autor:
Simon D.P. Baugh, Praveen K. Pabba, Joseph Barbosa, Eric Coulter, Urvi Desai, Jason P. Gay, Suma Gopinathan, Qiang Han, Rajee Hari, S. David Kimball, Huy V. Nguyen, Chi-You Ni, David R. Powell, Arian Smith, Kristen M. Terranova, Alan Wilson, Xuan-Chuan Yu, Victoria K. Lombardo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:3836-3839
The synthesis, SAR, and in vivo activity of inhibitors of delta-5 desaturase are described. Ring-constraint of the initial series provided access to a variety of in vitro active chemotypes, from which the indazole was selected. Examples from the inda