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Pharmacognostical characterization and formulation of herbal-based low-cost mosquito repellents from Elettaria cardamomum (Linn.) seed by using natural binder

Autor: Prosanta Pal, Rajat S. Das, Sonam Bhutia

Publikováno v: Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-10 (2021)

Background In the present scenario, the markets are flooded with chemical-based mosquito repellent products that are proven to be toxic to the human life especially to the children and quite expensive in term of cost. This present investigation was a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7713b3cc3184b27d1261543c22746a6e
https://doaj.org/article/bd99d1c8b6fb4b91b0e7c4397d81bb92

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An efficient deprotection method for 5′-[O,O-bis(pivaloyloxymethyl)]-(E)-vinylphosphonate containing oligonucleotides

Autor: Klaus Charisse, Christopher S. Theile, Ivan Zlatev, Jonathan O'Shea, Muthiah Manoharan, Rajat S. Das, Martin Maier, I. Ramesh Babu

Publikováno v: Tetrahedron. 74:6182-6186

5′-(E)-Vinylphosphonate (VP) is an effective bioisostere of the natural 5′-monophosphate in small interfering RNAs (siRNAs). Solid-phase synthesis of VP-siRNAs requires the use of appropriately protected VP-phosphoramidites in combination with op

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4b538b6b6329491f1b8673066fb18f0
https://doi.org/10.1016/j.tet.2018.09.008

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Synthesis and Biophysical Characterization of RNAs Containing 2'-Fluorinated Northern Methanocarbacyclic Nucleotides

Autor: Masaaki Akabane-Nakata, Shigeo Matsuda, Martin Egli, Muthiah Manoharan, Namrata D. Erande, Pawan Kumar, Rajat S. Das

Publikováno v: Organic letters. 21(7)

2'-Fluorinated Northern methanocarbacyclic (2'-F-NMC) nucleosides and phosphoramidites, based on a bicyclo[3.1.0]hexane scaffold bearing all four natural nucleobases (U, C, A, and G), were synthesized to enable exploration of this novel nucleotide mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f8bd31034ffbd0f97557d67e6f7efe
https://pubmed.ncbi.nlm.nih.gov/30892051

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Association of high-density lipoprotein, triglycerides, and homocysteine with bone mineral density in young Indian tribal women

Autor: Tapan Kumar Das, Geetanjali Sachdeva, Meena Desai, Rajat S. Das, Achhelal Pasi, Rucha Saoji, M. Ikram Khatkhatay

Publikováno v: Archives of osteoporosis. 13(1)

This study investigated association between lipids and homocysteine (Hcy) with bone mineral density (BMD) in young women as opposed to previous studies on elderly women. HDL, triglyceride, and Hcy are significantly associated with BMD in young women

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6058181660ce92b9e87d0da39f2c0c7a
https://pubmed.ncbi.nlm.nih.gov/30306279

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Effect of terminal 3′-hydroxymethyl modification of an RNA primer on nonenzymatic primer extension

Autor: Ayan Pal, Weicheng Zhang, Rajat S. Das, Larry W. McLaughlin, Megan Lang, Jack W. Szostak

Publikováno v: Chemical Communications. 52:11905-11907

The significance of the precise position of the hydroxyl at the 3'-end of an RNA primer for nonenzymatic template-directed primer extension is not well understood. We show that an RNA primer terminating in 3'-hydroxymethyl-2',3'-dideoxy-guanosine has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83ceadf6a8adb6ad68c161f114d72ad
https://doi.org/10.1039/c6cc06925h

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Crystal structure of Middle East respiratory syndrome coronavirus helicase

Autor: Wei Hao, Rajat S. Das, Sheng Cui, Meitian Wang, Ruiyun Han, Justyna Aleksandra Wojdyla, Rong Zhao, Muthiah Manoharan, Ivan Zlatev

Publikováno v: PLoS Pathogens
PLOS Pathogens
PLoS Pathogens, Vol 13, Iss 6, p e1006474 (2017)

Middle East respiratory syndrome coronavirus (MERS-CoV) remains a threat to public health worldwide; however, effective vaccine or drug against CoVs remains unavailable. CoV helicase is one of the three evolutionary most conserved proteins in nidovir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851e655cfce47f64aa8c6c16dc3397e3
http://europepmc.org/articles/PMC5501694

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Synthesis of [1,3, NH2-15N3] (5′S)-8,5′-cyclo-2′-deoxyguanosine

Autor: Rajat S. Das, Ashis K. Basu, Chanchal K. Malik

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 56:376-381

To facilitate NMR studies and low-level detection in biological samples by mass spectrometry, [1,3, NH2-15N3] (5′S)-8,5′-cyclo-2′-deoxyguanosine was synthesized from imidazole-4,5-dicarboxylic acid in 21 steps. The three 15N isotopes were intro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d452d2eb96d7907129ded8083d472412
https://doi.org/10.1002/jlcr.3051

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Evaluation of vascular effect of arsenic using in vivo assays

Autor: A K Gautam, Rajat S. Das, Sunil Kumar, Bharat Patel, Mugdha Tiwari, Sukhdev Acharya

Publikováno v: Environmental science and pollution research international. 24(18)

Arsenic (As) is an abundant toxicant present in groundwater and soil in various parts of the world including eastern part of India. The epidemiological studies have shown that arsenic exposure is linked to developmental defects and miscarriage. Place

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342e751360980c2062194fd224171de2
https://pubmed.ncbi.nlm.nih.gov/28516350

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