Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Rajat Madan"'
Autor:
Md Zahidul Alam, Rajat Madan
Publikováno v:
Toxins, Vol 16, Iss 6, p 241 (2024)
Clostridioides difficile, a Gram-positive anaerobic bacterium, is the leading cause of hospital-acquired antibiotic-associated diarrhea worldwide. The severity of C. difficile infection (CDI) varies, ranging from mild diarrhea to life-threatening con
Externí odkaz:
https://doaj.org/article/816e6b2cc85d4cb99b1e640e35d8bd09
Publikováno v:
Pathogens, Vol 13, Iss 2, p 118 (2024)
Clostridioides difficile is the most important cause of healthcare-associated diarrhea in the United States. The high incidence and recurrence rates of C. difficile infection (CDI), associated with high morbidity and mortality, pose a public health c
Externí odkaz:
https://doaj.org/article/ee740b34bfd44807a92c074fb50e04e6
Autor:
Olivia Horrigan, Shinsmon Jose, Anindita Mukherjee, Divya Sharma, Alexander Huber, Rajat Madan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Neutrophils are key first-responders in the innate immune response to C. difficile infection (CDI) and play a central role in disease pathogenesis. Studies have clearly shown that tissue neutrophil numbers need to be tightly regulated for optimal CDI
Externí odkaz:
https://doaj.org/article/7b333bdd34744028a9a7df3ec9ce497d
Autor:
Caitlin Naylor, Stacey Burgess, Rajat Madan, Erica Buonomo, Khadija Razzaq, Katherine Ralston, William A. Petri
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
ABSTRACT Amebiasis is an enteric infection caused by Entamoeba histolytica, with symptoms ranging in severity from asymptomatic colonization to dysentery. Humans with the Q223R leptin receptor mutation have increased susceptibility to amebiasis, but
Externí odkaz:
https://doaj.org/article/ff2bab89cf9d4992a8546e2eb960f95a
Autor:
George S. Deepe, Paul Spearman, Sing Sing Way, Michelle S M A Damen, Rajat Madan, Senad Divanovic, Pablo C Alarcon
Publikováno v:
Mucosal Immunology
Epidemiological evidence establishes obesity as an independent risk factor for increased susceptibility and severity to viral respiratory pneumonias associated with H1N1 influenza and SARS-CoV-2 pandemics. Given the global obesity prevalence, a bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950e1a0f8269813df14c5f60bb9f1e4c
https://doi.org/10.1038/s41385-021-00404-8
https://doi.org/10.1038/s41385-021-00404-8
Publikováno v:
Open Forum Infectious Diseases
Background Leptin is an adipose tissue-derived cytokine that plays a role in energy regulation and immune functions. High leptin levels and obesity have been associated with decreased risk of developing active TB. We aimed to characterize the associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e69749e150025bc0c83d649871bc34a
http://europepmc.org/articles/PMC8643816
http://europepmc.org/articles/PMC8643816
Autor:
Rajat Madan, Shinsmon Jose, Olivia Horrigan, Alexander Huber, Divya Sharma, Anindita Mukherjee
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
Neutrophils are key first-responders in the innate immune response to C. difficile infection (CDI) and play a central role in disease pathogenesis. Studies have clearly shown that tissue neutrophil numbers need to be tightly regulated for optimal CDI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b8f91e23663ec18d61ecc4725cf70b
https://doi.org/10.3389/fcimb.2021.619192
https://doi.org/10.3389/fcimb.2021.619192
Autor:
Heidi Andersen, Shinsmon Jose, Anindita Mukherjee, Rajat Madan, Maria E. Moreno-Fernandez, Kenneth D.R. Setchell, Olivia Horrigan, David B. Haslam, Senad Divanovic, Divya Sharma, Wujuan Zhang
Publikováno v:
Mucosal immunology
Severe Clostridiodes difficile infection (CDI) is life-threatening and responds poorly to treatment. Obesity is associated with development of severe CDI. Therefore, to define the mechanisms that exacerbate disease severity, we examined CDI pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a974dfdbe5bb8fedcf098b327e93625
https://pubmed.ncbi.nlm.nih.gov/32811993
https://pubmed.ncbi.nlm.nih.gov/32811993
Autor:
Mayuresh M. Abhyankar, Anindita Mukherjee, Lin Leng, Rajat Madan, Shinsmon Jose, Divya Sharma, Richard Bucala
Publikováno v:
Anaerobe. 53:56-63
Clostridium difficile is an important cause of nosocomial diarrhea in the western world. Toxins (A, B, and binary toxins) generated by C. difficile bacteria damage intestinal epithelial cells. Hallmarks of host response to C. difficile infection (CDI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d23cd6319a8dc34a84187f8d5f1988e
https://doi.org/10.1016/j.anaerobe.2018.06.014
https://doi.org/10.1016/j.anaerobe.2018.06.014
Autor:
Jianli Xue, Heidi Andersen, Anindita Mukherjee, David B. Haslam, Mayuresh M. Abhyankar, Shinsmon Jose, Rajat Madan
Publikováno v:
Mucosal immunology
Clostridium difficile is the leading cause of nosocomial infections in the United States. Clinical disease outcomes after C. difficile infection (CDI) are dependent on intensity of host inflammatory responses. Specifically, peak peripheral white bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bbfb847a4743b2f15f60725869e411
https://doi.org/10.1038/mi.2017.119
https://doi.org/10.1038/mi.2017.119