Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rajashree Ramaswamy"'
Publikováno v:
The Journal of Biochemistry. 171:555-565
An important feature of several neurodegenerative diseases is the formation of pathological structures containing aggregated proteins. The autophagy receptor optineurin/OPTN is frequently observed in these structures. The role played by optineurin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f087fcbe6e15ea1a820a11dc22af87
https://doi.org/10.1093/jb/mvac011
https://doi.org/10.1093/jb/mvac011
NLRP3 is a cytoplasmic receptor protein, which initiates caspase-1 mediated inflammatory immune response upon detection of invading pathogen or a wide array of internal distress signals. Several gain-of function mutations of NLRP3 cause hereditary di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a3c4e4156e981bcc958c3382d16078
https://doi.org/10.1101/2022.11.16.516705
https://doi.org/10.1101/2022.11.16.516705
NLRC4 [nucleotide-binding domain and leucine-rich repeat (NLR) family, caspase recruitment domain (CARD) containing 4] is an innate immune receptor, which, upon detection of certain pathogens or internal distress signals, initiates caspase-1-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e3ba6cc4cd875adf8a779b4894cbe2
https://europepmc.org/articles/PMC6815140/
https://europepmc.org/articles/PMC6815140/
Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation
Autor:
Gopalakrishna Ramachandran, Rajashree Ramaswamy, Shivranjani C. Moharir, Ghanshyam Swarup, Swasti Raychaudhuri, Megha Bansal, Shivali Rawat
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1865(11 Pt)
Optineurin (Optn) is an autophagy receptor that performs various functions in cargo-selective and non-selective autophagy. Here, we have identified and characterized a splice variant of mouse optineurin mRNA, which produces a truncated protein lackin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f711690283dc599933c9b5192eaf57a
https://pubmed.ncbi.nlm.nih.gov/30327196
https://pubmed.ncbi.nlm.nih.gov/30327196