Výsledky vyhledávání - "Rajasekar Janani"

miR-7-5p Antagomir Protects Against Inflammation-Mediated Apoptosis and Lung Injury via Targeting Raf-1 In Vitro and In Vivo

Autor: Divya Peethambaran, Bijesh Puthusseri, Gyanendra Kumar, Rajasekar Janani, Parvatam Giridhar, Vallikannan Baskaran

Publikováno v: Inflammation. 46:941-962

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae973d247c51fb07d6c2397f44136a67
https://doi.org/10.1007/s10753-023-01782-w

Zobrazit plný text záznamu

Lactucaxanthin Regulates the Cascade of Retinal Oxidative Stress, Endoplasmic Reticulum Stress and Inflammatory Signaling in Diabetic Rats

Autor: Elavarasan Anitha Rani, Rajasekar Janani, Muzaffar Jahangir Chonche, Baskaran Vallikannan

Publikováno v: Ocular immunology and inflammation.

The purpose of this study is to investigate the protective mechanism of lactucaxanthin against retinal angiogenesis in diabetic retinopathy.Streptozotocin-induced diabetic rats were orally gavaged with either lactucaxanthin or lutein (n=12/group) for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c87b1112b0a32a623451f7ba20d8381
https://pubmed.ncbi.nlm.nih.gov/35081014

Zobrazit plný text záznamu

Astaxanthin ameliorates hyperglycemia induced inflammation via PI3K/Akt–NF–κB signaling in ARPE-19 cells and diabetic rat retina

Autor: Rajasekar, Janani, Rani Elavarasan, Anitha, Peethambaran, Divya, Muzaffar, Chonche, Vallikannan, Baskaran

Publikováno v: European Journal of Pharmacology. 926:174979

Astaxanthin has been reported to possess anti-inflammatory effect but the exact mechanism in protecting the retinal pigment epithelial (RPE) cells is not clear. Hence, we hypothesized that astaxanthin could protect RPE by inhibiting ROS-mediated infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d8661190a9a1f8bed92d3c7df40406
https://doi.org/10.1016/j.ejphar.2022.174979

Zobrazit plný text záznamu

Lactucaxanthin protects retinal pigment epithelium from hyperglycemia-regulated hypoxia/ER stress/VEGF pathway mediated angiogenesis in ARPE-19 cell and rat model

Autor: Rani Elavarasan Anitha, Divya Peethambaran, Vallikannan Baskaran, Rajasekar Janani

Publikováno v: European Journal of Pharmacology. 899:174014

Hyperglycemia mediated perturbations in biochemical pathways induce angiogenesis in diabetic retinopathy (DR) pathogenesis. The present study aimed to investigate the protective effects of lactucaxanthin, a predominant lettuce carotenoid, on hypergly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40531c3ae30835e161e7a3eff1dace36
https://doi.org/10.1016/j.ejphar.2021.174014

Zobrazit plný text záznamu

Astaxanthin mediated regulation of VEGF through HIF1α and XBP1 signaling pathway: An insight from ARPE-19 cell and streptozotocin mediated diabetic rat model

Autor: Peethambaran Divya, Rajasekar Janani, Madan Kumar Perumal, Vallikannan Baskaran, Rani Elavarasan Anitha

Publikováno v: Experimental Eye Research. 206:108555

Breakdown of outer blood-retina barrier (BRB) has been associated with the pathogenesis of diabetic retinopathy (DR) and diabetic macular edema (DME). Vascular endothelial growth factor (VEGF) might play a detrimental role in the pathogenesis of DME,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719a00bdf014a034c0a6e715f340d871
https://doi.org/10.1016/j.exer.2021.108555

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání