Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rajas P. Kale"'
Autor:
Rajas P. Kale, Thanh Thanh L. Nguyen, J. Blair Price, Nathanael J. Yates, Ken Walder, Michael Berk, Roy V. Sillitoe, Abbas Z. Kouzani, Susannah J. Tye
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
The antidepressant actions of deep brain stimulation (DBS) are associated with progressive neuroadaptations within the mood network, modulated in part, by neurotrophic mechanisms. We investigated the antidepressant-like effects of chronic nucleus acc
Externí odkaz:
https://doaj.org/article/e38ba7c1b5d648cc87329b03f35a04fd
Autor:
Adam J Walker, Yesul eKim, J. Blair ePrice, Rajas P Kale, Jane A McGillivray, Michael eBerk, Susannah J Tye
Publikováno v:
Frontiers in Psychiatry, Vol 5 (2014)
The mood disorder prodrome is conceptualized as a symptomatic, but not yet clinically diagnosable stage of an affective disorder. Although a growing area, more focused research is needed in the pediatric population to better characterize psychopathol
Externí odkaz:
https://doaj.org/article/d75353e814224f71b7b4b538b6a072bc
Autor:
Rajas P. Kale, Chunling Hu, Susannah J. Tye, Thanh Thanh L. Nguyen, Lily C. Chan, Kristin Borreginne
Publikováno v:
Neuroscience & Biobehavioral Reviews. 92:7-15
Patients with mood disorders are at increased risk for metabolic dysfunction. Co-occurrence of the two conditions is typically associated with a more severe disease course and poorer treatment outcomes. The specific pathophysiological mechanisms unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e290a29fed10c709efec7297b6a7ad
https://doi.org/10.1016/j.neubiorev.2018.05.014
https://doi.org/10.1016/j.neubiorev.2018.05.014
Publikováno v:
Neuroprogression in Psychiatry
Stress, mitochondrial dysfunction, and inflammation are key pathophysiological processes contributing to neuroprogression in mental illness. These factors independently and collectively impact critical cellular mechanisms essential for healthy brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7dfc2fd1dd83c51768adbb6226e7922
https://doi.org/10.1093/med/9780198787143.003.0004
https://doi.org/10.1093/med/9780198787143.003.0004
Publikováno v:
Biological Psychiatry. 77:S142-S286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23ae45153372ce86bed218cb7b29030
https://doi.org/10.1016/j.biopsych.2015.03.007
https://doi.org/10.1016/j.biopsych.2015.03.007
Publikováno v:
Procedia Technology. 20:225-230
Preclinical research in optogeneticneuromodulation in small laboratory animals allows far greater control of neural circuitry. This precision provides an enhanced opportunity for understanding the neural basis of behavior. However, behavioral neurosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ba7e8bd92e099c2596fc5d74b7f051
https://doi.org/10.1016/j.protcy.2015.07.036
https://doi.org/10.1016/j.protcy.2015.07.036
Autor:
Ken Walder, Abbas Z. Kouzani, Susannah J. Tye, Pablo Patricio Zarate-Garza, Rajas P. Kale, Michael Berk
Publikováno v:
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 25(9)
Deep brain stimulation (DBS) devices deliver electrical pulses to neural tissue through an electrode. To study the mechanisms and therapeutic benefits of deep brain stimulation, murine preclinical research is necessary. However, conducting naturalist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f27cce15fc83ef77ab4e7afbcb0566
https://pubmed.ncbi.nlm.nih.gov/28113945
https://pubmed.ncbi.nlm.nih.gov/28113945
Publikováno v:
Series in BioEngineering ISBN: 9789811039553
Deep brain stimulation (DBS) is a widely used, efficacious neurosurgical treatment for neurological movement disorders. For example, electrical stimulation in the ventral intermediate thalamic nucleus drastically reduces tremor in patients with essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc34f39b29baeec03d2eef53bb1d43e
https://doi.org/10.1007/978-981-10-3957-7_4
https://doi.org/10.1007/978-981-10-3957-7_4
Publikováno v:
Series in BioEngineering ISBN: 9789811039553
Optogenetics has recently emerged to become one of the most significant tools for in vivo causal analysis of neural networks. Developed through decades of pioneering work, the optogenetic toolbox has expanded utility to allow virtually total control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::977b7c5cf231b06de02d7e5c85cfe354
https://doi.org/10.1007/978-981-10-3957-7_3
https://doi.org/10.1007/978-981-10-3957-7_3
Publikováno v:
EMBC
This paper presents a closed-loop optogenetic stimulation device to achieve online modulation of neurons. The device is designed to be mountable on small rodents in pre-clinical settings. Considering the size of rodents and the need for portability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f746b9453ec8327fcb467ed5913040e
https://doi.org/10.1109/embc.2016.7591911
https://doi.org/10.1109/embc.2016.7591911