Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Rajaraman Eri"'
Autor:
Rhian Stavely, Ainsley M. Robinson, Sarah Fraser, Rhiannon T. Filippone, Vanesa Stojanovska, Rajaraman Eri, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Current treatments for inflammatory bowel disease (IBD) are often inadequate due to limited efficacy and toxicity, leading to surgical resection in refractory cases. IBD’s broad and complex pathogenesis involving the immune system, enteric
Externí odkaz:
https://doaj.org/article/54b591fab2994f8291ce6a82ddc071cf
Autor:
Duyen Tran, Muhammad Ishaq, Cheng Yang, Tauseef Ahmad, Maurizio Ronci, Mariachiara Zuccarini, Stephen Myers, Courtney McGowan, Rajaraman Eri, Darren C. Henstridge, Sabrina Sonda, Vanni Caruso
Publikováno v:
Nutraceuticals, Vol 3, Iss 2, Pp 262-273 (2023)
Comorbidities associated with obesity, including diabetes and kidney diseases, greatly increase mortality rates and healthcare costs in obese patients. Studies in animal models and clinical trials have demonstrated that L-serine supplementation is a
Externí odkaz:
https://doaj.org/article/eb5beb1e75b64ef0a1cf760f057e85e8
Autor:
Muhammad Ishaq, Duyen Tran, Cheng Yang, Min Jia Ng, Arlene Kackanattil, Karthik Tata, Bianca J. Deans, Martin Bleasel, Silvia Vicenzi, Cameron Randall, Tauseef Ahmad, Carmelo Vicario, Maurizio Ronci, Mariachiara Zuccarini, Renata Ciccarelli, Paul Scowen, Dinesh Kumar Chellappan, Glenn Jacobson, Alex C. Bissember, Jason A. Smith, Rajaraman Eri, Juan J. Canales, Miguel Iglesias, Nuri Guven, Vanni Caruso
Publikováno v:
Endocrines, Vol 3, Iss 4, Pp 641-653 (2022)
Obesity produces a systemic low-grade inflammation associated with many adverse health conditions and, as we recently learned, with complications of COVID-19. Functional studies in animal models have demonstrated that asperuloside, an iridoid glycosi
Externí odkaz:
https://doaj.org/article/0c2bc3f7ac8942a488605278c3e78f17
Autor:
Ranmali Ranasinghe, Ruchira Fernando, Agampodi Promoda Perera, Madhur Shastri, Waheedha Basheer, Paul Scowen, Terry Pinfold, Rajaraman Eri
Publikováno v:
Gastrointestinal Disorders, Vol 2, Iss 1, Pp 27-47 (2020)
Background: The immune-modulator behaviour of the CCR6/CCL20 axis in multi -system pathophysiology and molecular signalling was investigated at two clinically significant time points, using a Ccr6—deficient mouse model of spontaneous colitis. Metho
Externí odkaz:
https://doaj.org/article/8cc7e7cd416f4048bf64cef828e4e56d
Autor:
Duyen Tran, Stephen Myers, Courtney McGowan, Darren Henstridge, Rajaraman Eri, Sabrina Sonda, Vanni Caruso
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Metabolic dysfunction, dysregulated differentiation, and atrophy of skeletal muscle occur as part of a cluster of abnormalities associated with the development of Type 2 diabetes mellitus (T2DM). Recent interest has turned to the attention of the rol
Externí odkaz:
https://doaj.org/article/48a786852f2243a8ad0fb9a862eeb3b2
Autor:
Rohit Gundamaraju, Ravichandra Vemuri, Ranga Rao Ambati, Lakshminarayana Rangaswamy, Wenying Lu, Rajaraman Eri D
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 2, Iss , Pp 100007- (2021)
Endoplasmic reticular stress (ERS) has been well-documented in escalating metastasis in clinical conditions. There has been a debate on its role in cancer portraying it as a double-edged sword. However, there is no evidence of increased cell migratio
Externí odkaz:
https://doaj.org/article/516ceb6689ae4648a733978634833184
Autor:
Tauseef Ahmad, Muhammad Ishaq, Samuel Karpiniec, Ahyoung Park, Damien Stringer, Neeraj Singh, Vishal Ratanpaul, Karen Wolfswinkel, Helen Fitton, Vanni Caruso, Rajaraman Eri
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2383 (2022)
Inflammatory bowel disease (IBD) is a complex and multifactorial disorder characterised by relapsing and remitting inflammation of the intestinal tract. Oxidative stress (OS) is the result of an imbalance between production and accumulation of reacti
Externí odkaz:
https://doaj.org/article/fc34a92f39df4ce1a599f854936b11c0
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Ulcerative colitis (UC) is characterised by chronic, relapsing, idiopathic, and multifactorial colon inflammation. Recent evidence suggests that mitochondrial dysfunction plays a critical role in the onset and recurrence of this disease. Previous rep
Externí odkaz:
https://doaj.org/article/d66da1f8cad94923963a969288aa4329
Autor:
Tanvi Shinde, Ravichandra Vemuri, Madhur D. Shastri, Agampodi Promoda Perera, Stephen Tristram, Roger Stanley, Rajaraman Eri
Publikováno v:
Journal of Functional Foods, Vol 52, Iss , Pp 100-108 (2019)
Probiotic Bacillus coagulans MTCC 5856 spores were evaluated in-vitro for their ability to survive simulated digestion, adhesion to colonic cells and immunomodulatory properties. The spores showed significant survival (92%) during simulated digestion
Externí odkaz:
https://doaj.org/article/0f99d0217c5046e98e4a7a4b249366ef
Autor:
Rhiannon T. Filippone, Narges Dargahi, Rajaraman Eri, Jose A. Uranga, Joel C. Bornstein, Vasso Apostolopoulos, Kulmira Nurgali
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7780 (2022)
Eosinophils and their regulatory molecules have been associated with chronic intestinal inflammation and gastrointestinal dysfunctions; eosinophil accumulation in the gut is prominent in inflammatory bowel disease (IBD). The chemokine receptor CCR3 p
Externí odkaz:
https://doaj.org/article/c20cd76b204b41f58f3da77ccac51b54