Spectrum of low-density lipoprotein receptor (LDLR) mutations in a cohort of Sri Lankan patients with familial hypercholesterolemia - a preliminary report.

Autor: Paththinige CS; Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, 00800, Sri Lanka. paththinige@yahoo.com.; Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura, Sri Lanka. paththinige@yahoo.com., Rajapakse JRDK; Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, 00800, Sri Lanka., Constantine GR; Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka., Sem KP; Translational Laboratory in Genetic Medicine, Agency for Science Technology and Research, National University of Singapore, Singapore, Singapore., Singaraja RR; Translational Laboratory in Genetic Medicine, Agency for Science Technology and Research, National University of Singapore, Singapore, Singapore., Jayasekara RW; Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, 00800, Sri Lanka., Dissanayake VHW; Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo, 00800, Sri Lanka.

Publikováno v: Lipids in health and disease [Lipids Health Dis] 2018 May 02; Vol. 17 (1), pp. 100. Date of Electronic Publication: 2018 May 02.

Generation of hyperlipidemic rabbit models using multiple sgRNAs targeted CRISPR/Cas9 gene editing system.

Autor: Yuan, Tingting¹, Zhong, Yi¹, Wang, Yingge², Zhang, Ting³, Lu, Rui^3,4, Zhou, Minya³, Lu, Yaoyao¹, Yan, Kunning¹, Chen, Yajie⁵, Hu, Zhehui⁶, Liang, Jingyan^1,4,7 jyliang@yzu.edu.cn, Fan, Jianglin⁵ jianglin@yamanashi.ac.jp, Cheng, Yong^3,4 chengyong@yzu.edu.cn

Publikováno v: Lipids in Health & Disease. 3/18/2019, Vol. 18 Issue 1, pN.PAG-N.PAG. 1p. 3 Color Photographs, 1 Diagram, 3 Charts.