Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Rajanikanth Vadigepalli"'
Autor:
Ankita Srivastava, Alexandra Manchel, John Waters, Manju Ambelil, Benjamin K. Barnhart, Jan B. Hoek, Ashesh P. Shah, Rajanikanth Vadigepalli
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Liver transplantation is an effective treatment for liver failure. There is a large unmet demand, even as not all donated livers are transplanted. The clinical selection criteria for donor livers based on histopathological evaluat
Externí odkaz:
https://doaj.org/article/ede3ef488ce14e5c94f3756b3fa9ef63
Autor:
Eden Hornung, Shaina Robbins, Ankita Srivastava, Sirisha Achanta, Jin Chen, Zixi Jack Cheng, James Schwaber, Rajanikanth Vadigepalli
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110549- (2024)
Summary: Vagal innervation is well known to be crucial to the maintenance of cardiac health, and to protect and recover the heart from injury. Only recently has this role been shown to depend on the activity of the underappreciated dorsal motor nucle
Externí odkaz:
https://doaj.org/article/dad9d0448c67447581b638f837600fc2
Autor:
Benjamin K. Barnhart, Toshiki Kan, Ankita Srivastava, Corinne E. Wessner, John Waters, Manju Ambelil, John R. Eisenbrey, Jan B. Hoek, Rajanikanth Vadigepalli
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Liver resection is an important surgical technique in the treatment of cancers and transplantation. We used ultrasound imaging to study the dynamics of liver regeneration following two-thirds partial hepatectomy (PHx) in male and female rats fed via
Externí odkaz:
https://doaj.org/article/883f227f143c486a86632a6eded40cf6
Autor:
Ahmet Erdemir, Lealem Mulugeta, Joy P. Ku, Andrew Drach, Marc Horner, Tina M. Morrison, Grace C. Y. Peng, Rajanikanth Vadigepalli, William W. Lytton, Jerry G. Myers
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract The complexities of modern biomedicine are rapidly increasing. Thus, modeling and simulation have become increasingly important as a strategy to understand and predict the trajectory of pathophysiology, disease genesis, and disease spread in
Externí odkaz:
https://doaj.org/article/774a511a58b2423096c0e5c34fef1b10
Autor:
Sean J. O’Sullivan, Damani McIntosh-Clarke, James Park, Rajanikanth Vadigepalli, James S. Schwaber
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability, autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) likely plays a prominent role in the neurological processes underlying these
Externí odkaz:
https://doaj.org/article/ee4e039aba274d2a8f26a523ce0f09d5
Autor:
Aalap Verma, Alexandra Manchel, Rahul Narayanan, Jan B. Hoek, Babatunde A. Ogunnaike, Rajanikanth Vadigepalli
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Rapid breakdown of hepatic glycogen stores into glucose plays an important role during intense physical exercise to maintain systemic euglycemia. Hepatic glycogenolysis is governed by several different liver-intrinsic and systemic factors such as hep
Externí odkaz:
https://doaj.org/article/198fe33895744c60bfc2aebe54b9b9e0
Autor:
Madhur Parihar, Liat Bendelac-Kapon, Michal Gur, Tali Abbou, Abha Belorkar, Sirisha Achanta, Keren Kinberg, Rajanikanth Vadigepalli, Abraham Fainsod
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Robustness is a feature of regulatory pathways to ensure signal consistency in light of environmental changes or genetic polymorphisms. The retinoic acid (RA) pathway, is a central developmental and tissue homeostasis regulatory signal, strongly depe
Externí odkaz:
https://doaj.org/article/f1794033bcd646a6a97139a9f24fb05a
Autor:
Alexandra Manchel, Radhakrishnan Mahadevan, Ramon Bataller, Jan B. Hoek, Rajanikanth Vadigepalli
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1157 (2022)
Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there is no efficacious treatment aiding most patients. AH manifests differently in individuals, with some patients showing debilitating symptoms more so than other
Externí odkaz:
https://doaj.org/article/a68634b292ea4c2bb491590b3482a0f0
Autor:
Alison Moss, Shaina Robbins, Sirisha Achanta, Lakshmi Kuttippurathu, Scott Turick, Sean Nieves, Peter Hanna, Elizabeth H. Smith, Donald B. Hoover, Jin Chen, Zixi (Jack) Cheng, Jeffrey L. Ardell, Kalyanam Shivkumar, James S. Schwaber, Rajanikanth Vadigepalli
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102713- (2021)
Summary: We developed a spatially-tracked single neuron transcriptomics map of an intrinsic cardiac ganglion, the right atrial ganglionic plexus (RAGP) that is a critical mediator of sinoatrial node (SAN) activity. This 3D representation of RAGP used
Externí odkaz:
https://doaj.org/article/ee23db1917214094b15a355b972b98d1
Autor:
Clara Leung, Shaina Robbins, Alison Moss, Maci Heal, Mahyar Osanlouy, Richard Christie, Navid Farahani, Corey Monteith, Jin Chen, Peter Hunter, Susan Tappan, Rajanikanth Vadigepalli, Zixi (Jack) Cheng, James S. Schwaber
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102795- (2021)
Summary: We developed and analyzed a single cell scale anatomical map of the rat intrinsic cardiac nervous system (ICNS) across four male and three female hearts. We find the ICNS has a reliable structural organizational plan across individuals that
Externí odkaz:
https://doaj.org/article/fe247268c56446aa98e12a51a962386b