Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rajanikanth Maganti"'
Autor:
Dae Young Jung, Umadevi Chalasani, Ning Pan, Randall H Friedline, Domenick A Prosdocimo, Minwoo Nam, Yoshihiro Azuma, Rajanikanth Maganti, Kristine Yu, Ashish Velagapudi, Bryan O'Sullivan-Murphy, Juliano L Sartoretto, Mukesh K Jain, Marcus P Cooper, Fumihiko Urano, Jason K Kim, Susan Gray
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77851 (2013)
Obesity places major demands on the protein folding capacity of the endoplasmic reticulum (ER), resulting in ER stress, a condition that promotes hepatic insulin resistance and steatosis. Here we identify the transcription factor, Kruppel-like factor
Externí odkaz:
https://doaj.org/article/5066e9fecbd54247996b5a839d53eb81
Autor:
Kirk M. Brown, Jayaprakash K. Nair, Maja M. Janas, Yesseinia I. Anglero-Rodriguez, Lan T. H. Dang, Haiyan Peng, Christopher S. Theile, Elena Castellanos-Rizaldos, Christopher Brown, Donald Foster, Jeffrey Kurz, Jeffrey Allen, Rajanikanth Maganti, Jing Li, Shigeo Matsuda, Matthew Stricos, Tyler Chickering, Michelle Jung, Kelly Wassarman, Jeff Rollins, Lauren Woods, Alex Kelin, Dale C. Guenther, Melissa W. Mobley, John Petrulis, Robin McDougall, Timothy Racie, Jessica Bombardier, Diana Cha, Saket Agarwal, Lei Johnson, Yongfeng Jiang, Scott Lentini, Jason Gilbert, Tuyen Nguyen, Samantha Chigas, Sarah LeBlanc, Urjana Poreci, Anne Kasper, Arlin B. Rogers, Saeho Chong, Wendell Davis, Jessica E. Sutherland, Adam Castoreno, Stuart Milstein, Mark K. Schlegel, Ivan Zlatev, Klaus Charisse, Mark Keating, Muthiah Manoharan, Kevin Fitzgerald, Jing-Tao Wu, Martin A. Maier, Vasant Jadhav
Publikováno v:
Nature biotechnology. 40(10)
Therapeutics based on short interfering RNAs (siRNAs) delivered to hepatocytes have been approved, but new delivery solutions are needed to target additional organs. Here we show that conjugation of 2'-O-hexadecyl (C16) to siRNAs enables safe, potent
Autor:
UmaDevi D. Chalasani, Rajanikanth Maganti, Juliano L. Sartoretto, Domenick A. Prosdocimo, Yoshihiro Azuma, Ashish Velagapudi, Susan Gray, Minwoo Nam, Marcus P. Cooper, Jason K. Kim, Mukesh K. Jain, Randall H. Friedline, Dae Young Jung, Ning Pan, Kristine Yu, Fumihiko Urano, Bryan O'Sullivan-Murphy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e77851 (2013)
PLoS ONE, Vol 8, Iss 10, p e77851 (2013)
Obesity places major demands on the protein folding capacity of the endoplasmic reticulum (ER), resulting in ER stress, a condition that promotes hepatic insulin resistance and steatosis. Here we identify the transcription factor, Kruppel-like factor