Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rajani M Shenoy"'
Autor:
Angela Mah, Yonglu Che, L. Elcavage, Tomas Bencomo, Zurab Siprashvili, Paul A. Khavari, Sumaira Z. Aasi, Rajani M Shenoy, Carolyn S. Lee
Publikováno v:
Oncogene
Collagens are the most abundant proteins in the body and comprise the basement membranes and stroma through which cancerous invasion occurs; however, a pro-neoplastic function for mutant collagens is undefined. Here we identify COL11A1 mutations in 6
Publikováno v:
Journal of Investigative Dermatology. 140:S15
Autor:
Zurab Siprashvili, Rajani M Shenoy, Yonglu Che, Joseph D. Puglisi, Brian J. Zarnegar, Danielle Johnston, Dan E. Webster, Ross J. Flockhart, Aparna Bhaduri, Alexander Ungewickell, Francesca Meschi, Paul A. Khavari
Publikováno v:
Nature Genetics. 48:53-58
Small nucleolar RNAs (snoRNAs) are conserved noncoding RNAs best studied as ribonucleoprotein (RNP) guides in RNA modification1,2. To explore their role in cancer, we compared 5,473 tumor-normal genome pairs to identify snoRNAs with frequent copy num
Autor:
Maochun Qin, Dimiter Kunnev, Rajani M. Shenoy, Robert W. Leach, Amy Freeland, Jianmin Wang, Steven C. Pruitt
Publikováno v:
Genome Research. 25:558-569
Minichromosome maintenance (MCM) proteins are loaded onto chromatin during G1-phase and define potential locations of DNA replication initiation. MCM protein deficiency results in genome instability and high rates of cancer in mouse models. Here we d
Publikováno v:
Journal of Investigative Dermatology. 139:S21
Autor:
Xiaomin Bao, Natalie Nady, Shiying Tao, Eon J. Rios, Glenn G. Wozniak, Joanna Wysocka, Paul A. Khavari, Angela Mah, Kun Qu, Zurab Siprashvili, Adam J. Rubin, Dan E. Webster, Brian J. Zarnegar, Rajani M Shenoy
Publikováno v:
Developmental Cell. 43:227-239.e5
Summary Somatic progenitors sustain tissue self-renewal while suppressing premature differentiation. Protein arginine methyltransferases (PRMTs) affect many processes; however, their role in progenitor function is incompletely understood. PRMT1 was f