Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Rajani Choudhuri"'
Autor:
Chandrasekharam N. Nagineni, Sarwat Naz, Rajani Choudhuri, Gadisetti V. R. Chandramouli, Murali C. Krishna, Jeffrey R. Brender, John A. Cook, James B. Mitchell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4835 (2021)
Understanding the global metabolic changes during the senescence of tumor cells can have implications for developing effective anti-cancer treatment strategies. Ionizing radiation (IR) was used to induce senescence in a human colon cancer cell line H
Externí odkaz:
https://doaj.org/article/36ec2a8f2891409b95e5163faf2e8f5d
Autor:
Yoichi Takakusagi, Shingo Matsumoto, Keita Saito, Masayuki Matsuo, Shun Kishimoto, Jonathan W Wojtkowiak, William DeGraff, Aparna H Kesarwala, Rajani Choudhuri, Nallathamby Devasahayam, Sankaran Subramanian, Jeeva P Munasinghe, Robert J Gillies, James B Mitchell, Charles P Hart, Murali C Krishna
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107995 (2014)
TH-302 is a hypoxia-activated prodrug (HAP) of bromo isophosphoramide mustard that is selectively activated within hypoxic regions in solid tumors. Our recent study showed that intravenously administered bolus pyruvate can transiently induce hypoxia
Externí odkaz:
https://doaj.org/article/0938aa4f3d55486b8f95bb9b28022c2c
Autor:
John A, Cook, Anastasia L, Sowers, Rajani, Choudhuri, Chandramouli, Gadisetti, Elijah F, Edmondson, Sangeeta, Gohain, Murali C, Krishna, James B, Mitchell
Publikováno v:
Journal of Radiation Research. 64:24-32
Non-lethal doses of ionizing radiation (IR) delivered to humans because of terrorist events, nuclear accidents or radiotherapy can result in carcinogenesis. Means of protecting against carcinogenesis are lacking. We questioned the role of the gut mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a41ac4f38acdaa89e20dab9f3a54616
https://doi.org/10.1093/jrr/rrac062
https://doi.org/10.1093/jrr/rrac062
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
Figure S1. Radiation survival curve of H460 cells treated with Palbociclib (A) Ribociclib (B) and Abemaciclib (C) at a dose of 1µM and 10µM administered either 24 hour pre-or post for indicated dose (Gy) of radiation exposure. (D) Full dose surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7418025bb05a6810a893ff8370b2b5
https://doi.org/10.1158/1078-0432.22474578
https://doi.org/10.1158/1078-0432.22474578
Autor:
Murali C. Krishna, James B. Mitchell, Peter L. Choyke, Nallathamby Devasahayam, Keita Saito, Elaine M. Jagoda, Stephen S. Adler, Rajani Choudhuri, Nobu Oshima, Shun Kishimoto, Tomohiro Seki, Jeffrey R. Brender, Kazutoshi Yamamoto
Molecular imaging approaches for metabolic and physiologic imaging of tumors have become important for treatment planning and response monitoring. However, the relationship between the physiologic and metabolic aspects of tumors is not fully understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3236e0d2875d5e1a344f2344ad69b8
https://doi.org/10.1158/0008-5472.c.6511479.v1
https://doi.org/10.1158/0008-5472.c.6511479.v1
Autor:
James B. Mitchell, Carter Van Waes, John A. Cook, Angela Thetford, Anastasia L. Sowers, Rajani Choudhuri, William DeGraff, Andrew J. Leiker
Supplementary Figure S4. The effects of PF-05212384 (10μM) on UMSCC46 radiation induced DNA damage repair.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08655e45d82a57b957b681b6c0b70a7b
https://doi.org/10.1158/1078-0432.22461104
https://doi.org/10.1158/1078-0432.22461104
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
experimental methods and all supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3e35a5ac2af2a594a674ce12cdbf1e
https://doi.org/10.1158/1078-0432.22474563.v1
https://doi.org/10.1158/1078-0432.22474563.v1
Autor:
James B. Mitchell, Carter Van Waes, John A. Cook, Angela Thetford, Anastasia L. Sowers, Rajani Choudhuri, William DeGraff, Andrew J. Leiker
Purpose: Radiation remains a mainstay for the treatment of nonmetastatic head and neck squamous cell carcinoma (HNSCC), a malignancy characterized by a high rate of PI3K/mTOR signaling axis activation. We investigated the ATP-competitive dual PI3K/mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c12d16ae5a0afde0689e83932db5ec0
https://doi.org/10.1158/1078-0432.c.6524696.v1
https://doi.org/10.1158/1078-0432.c.6524696.v1
Autor:
James B. Mitchell, John A. Cook, Askale Mathias, Janet Gamson, Maria Wissler, Rajani Choudhuri, Anastasia Sowers, Sarwat Naz
excel file table showing details of microsatellite markers used for cell line authentication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a50c4ef4543ae4007c9eef943fff57
https://doi.org/10.1158/1078-0432.22474566
https://doi.org/10.1158/1078-0432.22474566
Autor:
Murali C. Krishna, James B. Mitchell, Peter L. Choyke, Nallathamby Devasahayam, Keita Saito, Elaine M. Jagoda, Stephen S. Adler, Rajani Choudhuri, Nobu Oshima, Shun Kishimoto, Tomohiro Seki, Jeffrey R. Brender, Kazutoshi Yamamoto
Complete and detailed descriptions of materials and methods are in the supplementary information, including animal studies, image registration, hyperpolarized 13C MRI, 18F-FDG PET, EPR imaging, Western blot, Immunohistochemistry, and statistical anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a573026218dbb4c2a12e89b46e32e5a
https://doi.org/10.1158/0008-5472.22423344.v1
https://doi.org/10.1158/0008-5472.22423344.v1