Zobrazeno 1 - 10
of 1 512
pro vyhledávání: '"Rajan T"'
Autor:
Xiuying Li, Sowmya P. Lakshmi, Kiyoshi Uemasu, Zachary Lane, Rajan T. Reddy, Divay Chandra, Chunbin Zou, Yu Jiang, Toru Nyunoya
Publikováno v:
COPD, Vol 21, Iss 1 (2024)
AbstractObjective: To investigate the effects of cigarette smoke (CS) on Serine/Threonine Kinase 11 (STK11) and to determine STK11’s role in CS-induced airway epithelial cell cytotoxicity.Methods: STK11 expression levels in the lung tissues of smok
Externí odkaz:
https://doaj.org/article/a59d3a06d44c46958f69c2220a69414f
Autor:
Jeroen Molinger, John Whittle, Susie Cha, David MacLeod, Marat Fudim, Luis Ulloa, Christina Barkauskas, Zachary Healy, Krista L. Haines, Rajan T. Gupta, Henrik Endeman, Mathieu van der Jagt, Diederik Gommers, Jan Bakker, Paul E. Wischmeyer
Publikováno v:
Frontiers in Anesthesiology, Vol 3 (2024)
IntroductionThe COVID-19 pandemic brought unprecedented challenges to healthcare systems worldwide, particularly the often challenging physical recovery from critical illness. Among the myriad complications faced by these patients, ICU-acquired weakn
Externí odkaz:
https://doaj.org/article/c1678bfd796f45509c3428e33d0f7e17
Autor:
Jyothirmayi Velaga, Kae Jack Tay, Guanqi Hang, Yu Guang Tan, John S.P. Yuen, Melvin L.K. Chua, Rajan T. Gupta, Thomas J. Polascik, Nye Thane Ngo, Yan Mee Law
Publikováno v:
European Journal of Radiology Open, Vol 12, Iss , Pp 100556- (2024)
Externí odkaz:
https://doaj.org/article/b6ad009587d046e5aed10d2e0df36bd0
Autor:
Zoe D. Michael, Srinath Kotamarti, Rohith Arcot, Kostantinos Morris, Anand Shah, John Anderson, Andrew J. Armstrong, Rajan T. Gupta, Steven Patierno, Nadine J. Barrett, Daniel J. George, Glenn M. Preminger, Judd W. Moul, Kevin C. Oeffinger, Kevin Shah, Thomas J. Polascik
Publikováno v:
The World Journal of Men's Health, Vol 41, Iss 3, Pp 631-639 (2023)
Purpose: Prostate cancer (PCa) screening can lead to potential over-diagnosis/over-treatment of indolent cancers. There is a need to optimize practices to better risk-stratify patients. We examined initial longitudinal outcomes of mid-life men with
Externí odkaz:
https://doaj.org/article/dcb8b48249704eb5a9f6ba4e180b1147
Autor:
Jyothirmayi Velaga, Kae Jack Tay, Guanqi Hang, Yu Guang Tan, John SP Yuen, Melvin Chua, Rajan T. Gupta, Thomas J. Polascik, Nye Thane Ngo, Yan Mee Law
Publikováno v:
European Journal of Radiology Open, Vol 11, Iss , Pp 100529- (2023)
Objectives: Multiparametric magnetic resonance imaging (mpMRI) surveillance post focal cryotherapy (FT) of prostate cancer is challenging as post treatment artefacts alter mpMRI findings. In this initial experience, we assessed diagnostic performance
Externí odkaz:
https://doaj.org/article/18568f972d6f441ab3577a3bc8543e95
Autor:
Tian Zhang, Carl Morrison, Sarabjot Pabla, Jason Zhu, Matthew Zibelman, Shannon McCall, Sean T Glenn, Saby George, Yong Hee Lee, Landon C Brown, Chester Kao, Matthew K Labriola, Rajan T Gupta, Daniel J George, Laura J Tafe, Farshid Dayyani, Kunal Desai, Moshe C Ornstein, Emily Kinsey, Jennifer Tran, Konstantin H Dragnev, Mary K Nesline
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Immunotherapy combinations including ipilimumab and nivolumab are now the standard of care for untreated metastatic renal cell carcinoma (mRCC). Biomarkers of response are lacking to predict patients who will have a favorable or unfavorabl
Externí odkaz:
https://doaj.org/article/9b968140c98748eb94a5b6265a763e29
Autor:
Andrew L. Laccetti, Benjamin Garmezy, Lianchun Xiao, Minas Economides, Aradhana Venkatesan, Jianjun Gao, Eric Jonasch, Paul Corn, Amado Zurita‐Saavedra, Landon C. Brown, Chester Kao, Emily N. Kinsey, Rajan T. Gupta, Michael R. Harrison, Andrew J. Armstrong, Daniel J. George, Nizar Tannir, Pavlos Msaouel, Amishi Shah, Tian Zhang, Matthew T. Campbell
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2341-2349 (2021)
Abstract Introduction Two separate antiangiogenic tyrosine kinase inhibitors (TKIs) and immunotherapy (IO) combinations are FDA‐approved as front‐line treatment for metastatic renal cell carcinoma (mRCC). Little is known about off‐protocol and
Externí odkaz:
https://doaj.org/article/93fb0ccf60b5470ca6cdd487ce1a82ce
Autor:
Christina Sze, Efrat Tsivian, Kae Jack Tay, Ariel A. Schulman, Leah G. Davis, Rajan T. Gupta, Thomas J. Polascik
Publikováno v:
BMC Urology, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Due to their location away from the nerve bundles, anterior prostate cancers (APC) represent a rational target for image-guided cryoablation. This report describes the feasibility and short-term outcomes of anterior focal cryosurg
Externí odkaz:
https://doaj.org/article/fedd05a81aaa4050b92c232482a478f6
Autor:
Matthew D. Tucker, Jason Zhu, Daniele Marin, Rajan T. Gupta, Santosh Gupta, William R. Berry, Sundhar Ramalingam, Tian Zhang, Michael Harrison, Yuan Wu, Patrick Healy, Stacey Lisi, Daniel J. George, Andrew J. Armstrong
Publikováno v:
Cancer Medicine, Vol 8, Iss 10, Pp 4644-4655 (2019)
Abstract Background Pembrolizumab is approved for patients with metastatic, microsatellite instability (MSI)‐high or mismatch repair‐deficient (dMMR) solid tumors. However, very few men with prostate cancer were included in these initial studies.
Externí odkaz:
https://doaj.org/article/003ea2a11f594b2c9c3a564cda4a8f56
Autor:
Ramy Sedhom, Santosh Gupta, Yuan Wu, Jason Zhu, Daniele Marin, Michael R Harrison, Landon C Brown, Matthew D Tucker, Eric B Schwartz, Chester Kao, Matthew K Labriola, Rajan T Gupta, Daniel J George, Emmanuel S Antonarakis, Andrew J Armstrong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may have improved outcomes with immune checkpoint inhibitors (ICI).Methods We co
Externí odkaz:
https://doaj.org/article/f6c317e45ad243c18c3fdb3ae41b8601