Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Rajan Pandey"'
Autor:
Yong Liu, Jing Huang, Rajan Pandey, Pengyuan Liu, Bhavika Therani, Qiongzi Qiu, Sridhar Rao, Aron M. Geurts, Allen W. Cowley, Andrew S. Greene, Mingyu Liang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background A common feature of single-cell RNA-seq (scRNA-seq) data is that the number of cells in a cell cluster may vary widely, ranging from a few dozen to several thousand. It is not clear whether scRNA-seq data from a small number of ce
Externí odkaz:
https://doaj.org/article/47cf9339076f4b95a6c6e5db2b4711be
Autor:
Priya Gupta, Rajan Pandey, Vandana Thakur, Sadaf Parveen, Inderjeet Kaur, Ashutosh Panda, Rashmita Bishi, Sonali Mehrotra, Asif Akhtar, Dinesh Gupta, Asif Mohmmed, Pawan Malhotra
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 10, Pp 662-674 (2022)
Abstract Hemoglobin degradation is crucial for the growth and survival of Plasmodium falciparum in human erythrocytes. Although the process of Hb degradation has been studied in detail, the mechanisms of Hb uptake remain ambiguous to date. Here, we c
Externí odkaz:
https://doaj.org/article/5b0ffeec1a6849c0b030b340e989d3bf
Publikováno v:
FEBS Open Bio, Vol 11, Iss 7, Pp 1921-1929 (2021)
Post‐translational modifications, especially reversible phosphorylation, are among the most common mechanisms that regulate protein function and biological processes in Plasmodium species. Of the Plasmodium phosphatases, phosphatase of regenerating
Externí odkaz:
https://doaj.org/article/d41a73a6c42d424d90affa2814cc5673
Autor:
Mohammad Zeeshan, Rajan Pandey, Amit Kumar Subudhi, David J. P. Ferguson, Gursimran Kaur, Ravish Rashpa, Raushan Nugmanova, Declan Brady, Andrew R. Bottrill, Sue Vaughan, Mathieu Brochet, Mathieu Bollen, Arnab Pain, Anthony A. Holder, David S. Guttery, Rita Tewari
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Zeeshan et al. used real-time live-cell and ultrastructural imaging, conditional gene knockdown, RNA-seq and proteomic approaches to implicate Plasmodium PP1 in both mitotic exit and, potentially, establishing cell polarity during zygote development
Externí odkaz:
https://doaj.org/article/b7773fc630264f8886ca813289e58978
Publikováno v:
ACS Omega, Vol 6, Iss 27, Pp 17510-17522 (2021)
Externí odkaz:
https://doaj.org/article/277ffeed8bbd4ba28298b5bee29a77ae
Autor:
Aurélia C Balestra, Mohammad Zeeshan, Edward Rea, Carla Pasquarello, Lorenzo Brusini, Tobias Mourier, Amit Kumar Subudhi, Natacha Klages, Patrizia Arboit, Rajan Pandey, Declan Brady, Sue Vaughan, Anthony A Holder, Arnab Pain, David JP Ferguson, Alexandre Hainard, Rita Tewari, Mathieu Brochet
Publikováno v:
eLife, Vol 9 (2020)
Cell cycle transitions are generally triggered by variation in the activity of cyclin-dependent kinases (CDKs) bound to cyclins. Malaria-causing parasites have a life cycle with unique cell-division cycles, and a repertoire of divergent CDKs and cycl
Externí odkaz:
https://doaj.org/article/a33b722ce023496bbb31366d6e514108
Autor:
Rajan Pandey, Steven Abel, Matthew Boucher, Richard J. Wall, Mohammad Zeeshan, Edward Rea, Aline Freville, Xueqing Maggie Lu, Declan Brady, Emilie Daniel, Rebecca R. Stanway, Sally Wheatley, Gayani Batugedara, Thomas Hollin, Andrew R. Bottrill, Dinesh Gupta, Anthony A. Holder, Karine G. Le Roch, Rita Tewari
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1883-1897.e6 (2020)
Summary: Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear. Here we
Externí odkaz:
https://doaj.org/article/aae73a6a1b1c42aabd262685b6842123
Autor:
Noah Machuki Onchieku, Sonam Kumari, Rajan Pandey, Vaibhav Sharma, Mohit Kumar, Arunaditya Deshmukh, Inderjeet Kaur, Asif Mohmmed, Dinesh Gupta, Daniel Kiboi, Naseem Gaur, Pawan Malhotra
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1465 (2021)
Reduced sensitivity of the human malaria parasite, Plasmodium falciparum, to Artemisinin and its derivatives (ARTs) threatens the global efforts towards eliminating malaria. ARTs have been shown to cause ubiquitous cellular and genetic insults, which
Externí odkaz:
https://doaj.org/article/12dac69b553b417182b3d7f7b001afec
Publikováno v:
Molecules, Vol 26, Iss 9, p 2742 (2021)
The serine protease, DegP exhibits proteolytic and chaperone activities, essential for cellular protein quality control and normal cell development in eukaryotes. The P. falciparum DegP is essential for the parasite survival and required to combat th
Externí odkaz:
https://doaj.org/article/26a22666bd104cbd84e2b4dd8536bfdd
Autor:
David S. Guttery, Abhinay Ramaprasad, David J. P. Ferguson, Mohammad Zeeshan, Rajan Pandey, Declan Brady, Anthony A. Holder, Arnab Pain, Rita Tewari
Publikováno v:
Cells, Vol 9, Iss 12, p 2590 (2020)
The meiotic recombination 11 protein (MRE11) plays a key role in DNA damage response and maintenance of genome stability. However, little is known about its function during development of the malaria parasite Plasmodium. Here, we present a functional
Externí odkaz:
https://doaj.org/article/1311cbb1d3b6487baf891fba1dcd5837