Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Rajan Lamichhane"'
Autor:
Shushu Wei, Niloofar Gopal Pour, Sriram Tiruvadi-Krishnan, Arka Prabha Ray, Naveen Thakur, Matthew T. Eddy, Rajan Lamichhane
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Mutations that constitutively activate G protein-coupled receptors (GPCRs), known as constitutively activating mutations (CAMs), modify cell signaling and interfere with drugs, resulting in diseases with limited treatment options. We utilize
Externí odkaz:
https://doaj.org/article/a5791267b9534817a20ef741b4663262
Publikováno v:
Life, Vol 13, Iss 9, p 1933 (2023)
Introduction: Metabolic syndrome amplifies the risk of gestational diabetes, preeclampsia, and preterm labor in pregnant women. Similarly, women with substance use disorder have worsened obstetric and birth outcomes. Despite these two conditions bein
Externí odkaz:
https://doaj.org/article/a6aea950d73a4bcfae6ddc0628286eb8
Autor:
Aayush Adhikari, Surendra Khanal, Sagar Rana Magar, Srijana Thapa, Srijana Khati, Rajan Lamichhane, Kundan Marasini
Publikováno v:
Case Reports in Infectious Diseases, Vol 2023 (2023)
Aspergilloma (a saprophytic infection) typically colonizes lung cavities due to underlying diseases such as tuberculosis, bronchiectasis, cavitary lung cancer, sarcoidosis, and pulmonary infarctions. Rarely, aspergilloma has been noted within a hydat
Externí odkaz:
https://doaj.org/article/a4c6fae516304d469b6bc94657aef417
Autor:
Aayush Adhikari, Suraj Shrestha, Prabin Bhattarai, Surendra Khanal, Rajan Lamichhane, Ramesh Balayar, Sobin Panta, Kundan Marasini
Publikováno v:
Clinical Case Reports, Vol 10, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/25314d6051dd4aa5a54884572f16b387
Autor:
Gaurav Nepal, Sanjeev Kharel, Riwaj Bhagat, Megan A Coghlan, Jayant K Yadav, Stella Goeschl, Rajan Lamichhane, Subash Phuyal, Rajeev Ojha, Gentle S Shrestha
Publikováno v:
Journal of Central Nervous System Disease, Vol 14 (2022)
Background Cerebral venous thrombosis (CVT) is a rare thrombotic condition which is traditionally treated with anti-coagulation therapy. Subsets of patients with severe CVT have been treated with endovascular thrombectomy (EVT). Despite the high esti
Externí odkaz:
https://doaj.org/article/a57361ec04a94e339e72d91f151b68d1
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101535- (2022)
Summary: We describe production of the human A2A adenosine receptor (A2AAR), a class A G protein-coupled receptor (GPCR) for 19F-NMR and single-molecule fluorescence (SMF) spectroscopy. We explain in detail steps shared between the two sample prepara
Externí odkaz:
https://doaj.org/article/15f241271f524010b982028ab1f807e4
Autor:
Gentle Sunder Shrestha, Babin Basnet, Gaurav Nepal, Rajan Lamichhane, Prabin Gaire, Rayana Shrestha, Sabin Thapalia
Publikováno v:
Clinical Case Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract No hemorrhagic manifestations, presence of platelet clumps on the peripheral blood smear, normal manual count, and normal autoanalyzer count after collecting blood in citrate vial help confirm the diagnosis of EDTA‐dependent thrombocytopen
Externí odkaz:
https://doaj.org/article/bc55dc14590e4b29b1a026e965514d08
Publikováno v:
eLife, Vol 10 (2021)
Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the phy
Externí odkaz:
https://doaj.org/article/8497dd7c5ad04430a6d77330c89d932c
Publikováno v:
Bio-Protocol, Vol 7, Iss 12 (2017)
Activation of G protein-coupled receptors (GPCRs) by agonist ligands is mediated by a transition from an inactive to active receptor conformation. We describe a novel single-molecule assay that monitors activation-linked conformational transitions in
Externí odkaz:
https://doaj.org/article/b31425b52d1741418e7f8c7b4acf34af
Publikováno v:
Journal of Clinical Medicine, Vol 3, Iss 1, Pp 153-166 (2014)
This study examines the association between state and county unemployment rates and individuals’ body weight status during the latest recession in the U.S. We used the U.S. Behavioral Risk Factor Surveillance System (BRFSS) data in 2007, 2009 and 2
Externí odkaz:
https://doaj.org/article/0e6f0218a78a4d2d8aa6eba02760b684