Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rajamanickam Murugan"'
Autor:
Rajamanickam Murugan
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0302679 (2024)
We derive approximate expressions for pre- and post-steady state regimes of the velocity-substrate-inhibitor spaces of the Michaelis-Menten enzyme kinetic scheme with fully and partial competitive inhibition. Our refinement over the currently availab
Externí odkaz:
https://doaj.org/article/3524112c05e24a3288e30790c5053a71
Autor:
Rajamanickam Murugan, Gabriel Kreiman
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5115-5135 (2022)
Response time decides how fast a gene can react against an external signal at the transcription level in a signalling cascade. The steady state protein levels of the responding genes decide the coupling between two consecutive members of a signalling
Externí odkaz:
https://doaj.org/article/ccd2245d64f3426191e24ca997ee94d5
Autor:
Nimelan Veerasamy, Sarata Kumar Sahoo, Rajamanickam Murugan, Sharayu Kasar, Kazumasa Inoue, Masahiro Fukushi, Thennaarassan Natarajan
Publikováno v:
Molecules, Vol 26, Iss 24, p 7510 (2021)
Inductively coupled plasma mass spectrometry (ICP-MS) has been used to measure the concentration of trace and rare earth elements (REEs) in soils. Geochemical certified reference materials such as JLk-1, JB-1, and JB-3 were used for the validation of
Externí odkaz:
https://doaj.org/article/b31a6b071ad1426182b57086922dc3ba
Publikováno v:
Molecules, Vol 25, Iss 21, p 5178 (2020)
Two different digestion methods—microwave digestion (Mw) and Savillex digestion (Sx)—were used to evaluate the best quality control for analysis of the rare earth elements, Th and U in the geochemical certified reference material JSd-2, supplied
Externí odkaz:
https://doaj.org/article/7494105437fc43029aa050698adabadf
Autor:
Nimelan Veerasamy, Asako Takamasa, Rajamanickam Murugan, Sharayu Kasar, Tatsuo Aono, Kazumasa Inoue, Masahiro Fukushi, Sarata Kumar Sahoo
Publikováno v:
Molecules, Vol 25, Iss 9, p 2138 (2020)
A new chemical separation has been developed to isolate uranium (U) using two UTEVA columns to minimize iron and thorium interferences from high background area soil samples containing minerals like monazites and ilmenite. The separation method was s
Externí odkaz:
https://doaj.org/article/5ad56e46863640baa495f0a9668e4a49
Publikováno v:
Molecules, Vol 25, Iss 8, p 1956 (2020)
Precise tellurium (Te) isotope ratio measurement using mass spectrometry is a challenging task for many decades. In this paper, Te isotope ratio measurements using multi-collector inductively coupled plasma mass spectrometry (MC–ICP–MS) in terres
Externí odkaz:
https://doaj.org/article/39dea08aa5cf42ee8fb8f2d0720fdef7
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153172 (2016)
Renaturation of the complementary single strands of DNA is one of the important processes that requires better understanding in the view of molecular biology and biological physics. Here we develop a stochastic dynamical model on the DNA renaturation
Externí odkaz:
https://doaj.org/article/2a2b8a0c4ce24459b095afbef62f9ef8
Autor:
Rajamanickam Murugan
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104328 (2014)
We develop a detailed theoretical framework for various types of transcription factor gene oscillators. We further demonstrate that one can build genetic-oscillators which are tunable and robust against perturbations in the critical control parameter
Externí odkaz:
https://doaj.org/article/daf14bfdd8104304b27429a054a96e85
Autor:
Rajamanickam Murugan
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41027 (2012)
Feedforward loops (FFLs) consist of three genes which code for three different transcription factors A, B and C where B regulates C and A regulates both B and C. We develop a detailed model to describe the dynamical behavior of various types of coher
Externí odkaz:
https://doaj.org/article/211950c7d6424f19ab6e9c8502b2b4b6
Autor:
Rajamanickam Murugan, Gabriel Kreiman
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 11, p e1002747 (2012)
Eukaryotic genes are typically split into exons that need to be spliced together to form the mature mRNA. The splicing process depends on the dynamics and interactions among transcription by the RNA polymerase II complex (RNAPII) and the spliceosomal
Externí odkaz:
https://doaj.org/article/f03e997a5c534aacab24fabef75bb328