Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Rajamanickam Baskar"'
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 3, Pp 193-199 (2012)
In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. However with its increasing incidence, the clinical management of cancer continues to be a challenge for the 21st c
Externí odkaz:
https://doaj.org/article/d9892bb8b0c94de5b7a73baca1b14046
Autor:
Resham Lal Gurung, Shi Ni Lim, Aik Kia Khaw, Jasmine Fen Fen Soon, Kirthan Shenoy, Safiyya Mohamed Ali, Manikandan Jayapal, Swaminathan Sethu, Rajamanickam Baskar, M Prakash Hande
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12124 (2010)
A major concern of cancer chemotherapy is the side effects caused by the non-specific targeting of both normal and cancerous cells by therapeutic drugs. Much emphasis has been placed on discovering new compounds that target tumour cells more efficien
Externí odkaz:
https://doaj.org/article/50c0ad157f5a41a6ad47f6e84eb6d71d
Autor:
Rajamanickam, Baskar, Govindaraju, Bharathkumar, Selvaraaju, Selvapriya Sikkal, Thangarasu, Hemadevi, Abdul kareem, Shameem Fathima
Publikováno v:
Journal of Advanced Zoology; 2024, Vol. 45 Issue 2, p395-406, 12p
Autor:
Koji Itahana, Rajamanickam Baskar
Publikováno v:
International Journal of Medical Sciences
Globally, morbidity and mortality due to cancer are predicted to increase in both men and women in the coming decades. Furthermore, it is estimated that two thirds of these cancer-related deaths will occur in low-and middle-income countries (LMIC). I
Autor:
Grace Kah Mun Low, Neisha Sundaram, Dimphy Zeegers, Rajamanickam Baskar, M. Prakash Hande, Adayabalam S. Balajee, Pallavee Srivastava, Shriram Venkatesan, Shu Wen Koh, Swaminathan Sethu, Oleg Belyakov, Manikandan Jayapal, Birendranath Banerjee
Publikováno v:
Genome Integrity
Humans are exposed to ionizing radiation not only through background radiation but also through the ubiquitous presence of devices and sources that generate radiation. With the expanded use of radiation in day-to-day life, the chances of accidents or
Publikováno v:
Journal of Cancer
Background: Non-homologous end joining (NHEJ) is the main repair pathway for DNA double strand breaks (DSBs) induced by ionizing radiation in mammalian cells. Subsets of cancer patients are hypersensitive to radiotherapy after standard doses. We soug
Publikováno v:
International Journal of Medical Sciences
In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. However with its increasing incidence, the clinical management of cancer continues to be a challenge for the 21st c
Autor:
Philip K. Moore, Rajamanickam Baskar
Publikováno v:
Journal of Cellular and Molecular Medicine
Dear Editor: In recent years, it has become clear that hydrogen sulphide (H2S) plays a number of biological roles and may function as a novel gasotransmitter in the body alongside nitric oxide (NO) and carbon monoxide (CO) [1]. H2S is synthesized nat
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:125-134
Studies over the last several years have revealed the existence of a biological phenomenon known as "bystander effect", wherein cells that are not exposed to radiation elicit a similar response to that of irradiated cells. Understanding the mechanism
Autor:
Birendranath Banerjee, Miranti Silasudjana, Masao Suzuki, Aik Kia Khaw, Rajamanickam Baskar, M. Prakash Hande
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 625:134-144
The aim of the present study is to investigate the effect of histone deacetylase inhibitor, trichostatin A (TSA) on the cell growth, apoptosis, genomic DNA damage and the expression of telomerase and associated factors in human normal and brain cance