Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rajaguru Aradhya"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5423 (2024)
The highly conserved Notch pathway, a pillar of juxtacrine signaling, orchestrates intricate intercellular communication, governing diverse developmental and homeostatic processes through a tightly regulated cascade of proteolytic cleavages. This pat
Externí odkaz:
https://doaj.org/article/d3300c8d76f84dbeba4c1e03b81fb184
Publikováno v:
Bio-Protocol, Vol 13, Iss 3 (2023)
Adult muscle stem cells (MuSCs) show remarkable capability in repairing injured tissues. Studying MuSCs in suitable model organisms, which show strong homology with vertebrate counterparts, helps in dissecting the mechanisms regulating their behavior
Externí odkaz:
https://doaj.org/article/e062fc58f8bb48deb1492b021bd74297
Publikováno v:
eLife, Vol 4 (2015)
How stem cells specified during development keep their non-differentiated quiescent state, and how they are reactivated, remain poorly understood. Here, we applied a Drosophila model to follow in vivo behavior of adult muscle precursors (AMPs), the t
Externí odkaz:
https://doaj.org/article/3c97432c5dfe48c6ad0ab1d618011487
Autor:
Subhash Rajpurohit, Pooran Singh Solanki, Harshad Mayekar, Homica Arya, Rajaguru Aradhya, Prashanth Suravajhala, Volker Loeschcke
Growing summer season, increased anthropogenic activities poses a continual challenge to resident species Ectotherms like insects are especially vulnerable to rapid climatic changes. High-altitude tropical insect populations have been rarely examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7918536dd20898e9647c18b1f9320f55
https://doi.org/10.1101/2022.09.10.507406
https://doi.org/10.1101/2022.09.10.507406
Publikováno v:
FEBS Letters. 594:2061-2083
In multicellular organisms, cell proliferation must be tightly coordinated with other developmental processes to form functional tissues and organs. Despite significant advances in our understanding of how the cell cycle is controlled by conserved ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b90ac19e55338d1c4f4328bda4b50b
https://doi.org/10.1002/1873-3468.13805
https://doi.org/10.1002/1873-3468.13805
Autor:
Arya, Aloor, Rajaguru, Aradhya, Parvathy, Venugopal, Bipin, Gopalakrishnan Nair, Renuka, Suravajhala
Publikováno v:
Biochemical Pharmacology. 206:115335
Glycan is an essential molecule that controls and drives life in a precise direction. The paucity of research in glycobiology may impede the significance of its role in the pandemic guidelines. The SARS-CoV-2 spike protein is heavily glycosylated, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b32d4b24c9472fc7d25a0380006a846
https://doi.org/10.1016/j.bcp.2022.115335
https://doi.org/10.1016/j.bcp.2022.115335
Autor:
Rajaguru, Aradhya, Krzysztof, Jagla
Publikováno v:
Advances in experimental medicine and biology. 1227
Notch plays multiple roles both in development and in adult tissue homeostasis. Notch was first identified in Drosophila in which it has then been extensively studied. Among the flag-ship Notch functions we could mention its capacity to keep precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cf8531a7082f6ca8d9508a5a3d8ff99
https://pubmed.ncbi.nlm.nih.gov/32072503
https://pubmed.ncbi.nlm.nih.gov/32072503
Autor:
Rajaguru Aradhya, Krzysztof Jagla
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030364212
Notch plays multiple roles both in development and in adult tissue homeostasis. Notch was first identified in Drosophila in which it has then been extensively studied. Among the flag-ship Notch functions we could mention its capacity to keep precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa50a9ebb32f122e7b2d82579fdf368d
https://doi.org/10.1007/978-3-030-36422-9_9
https://doi.org/10.1007/978-3-030-36422-9_9
miRNA suppression of a Notch repressor directs non-neuronal fate in Drosophila mechanosensory organs
Autor:
Boris Shklyar, Joshua Kavaler, Eric C. Lai, Brian Joseph, Rajaguru Aradhya, Luis F. de Navas, Hong Duan
Publikováno v:
The Journal of Cell Biology
Large-scale knockout studies suggest that most miRNAs are phenotypically dispensable. However, Kavaler et al. show here that developmental specification toward a non-neuronal fate in the Drosophila melanogaster peripheral sensory organ lineage depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af74baf2a139578e8349fbc5b98dad1e
http://europepmc.org/articles/PMC5800810
http://europepmc.org/articles/PMC5800810
Autor:
Josefa Steinhauer, Jaaved Mohammed, Adam Siepel, Shu Kondo, Jeffrey P. Vedanayagam, Rajaguru Aradhya, Sogol Eizadshenass, Lijuan Kan, Nan Pang, Eric C. Lai
Publikováno v:
Genes & Development. 31:1841-1846
Relatively little is known about the in vivo functions of newly emerging genes, especially in metazoans. Although prior RNAi studies reported prevalent lethality among young gene knockdowns, our phylogenomic analyses reveal that young Drosophila gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e7ab3356024c1911a8b4118c5d9d01
https://doi.org/10.1101/gad.303131.117
https://doi.org/10.1101/gad.303131.117