Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Rajaganapathi Jagannathan"'
Autor:
Krithika Rao, Elizabeth Rochon, Anuradha Singh, Rajaganapathi Jagannathan, Zishan Peng, Haris Mansoor, Bing Wang, Mousumi Moulik, Manling Zhang, Anita Saraf, Paola Corti, Sruti Shiva
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109146- (2024)
Summary: The endogenous mechanisms that propagate cardiomyocyte differentiation and prevent de-differentiation remain unclear. While the expression of the heme protein myoglobin increases by over 50% during cardiomyocyte differentiation, a role for m
Externí odkaz:
https://doaj.org/article/37c38e76530243ab8a47fc3827429492
Autor:
Feng Li, Ruya Liu, Vinny Negi, Ping Yang, Jeongkyung Lee, Rajaganapathi Jagannathan, Mousumi Moulik, Vijay K. Yechoor
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111904- (2023)
Summary: TEAD1 and the mammalian Hippo pathway regulate cellular proliferation and function, though their regulatory function in β cells remains poorly characterized. In this study, we demonstrate that while β cell-specific TEAD1 deletion results i
Externí odkaz:
https://doaj.org/article/58507afec47146c5b6c53a63b91d1ced
Autor:
Ruya Liu, Rajaganapathi Jagannathan, Feng Li, Jeongkyung Lee, Nikhil Balasubramanyam, Byung S Kim, Ping Yang, Vijay K Yechoor, Mousumi Moulik
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212017 (2019)
Adult heart size is determined predominantly by the cardiomyocyte number and size. The cardiomyocyte number is determined primarily in the embryonic and perinatal period, as adult cardiomyocyte proliferation is restricted in comparison to that seen d
Externí odkaz:
https://doaj.org/article/95b43d1709ae4f218ddab65b196a37bf
Autor:
Anushree Bhatnagar, Hamiyet Unal, Rajaganapathi Jagannathan, Suma Kaveti, Zhong-Hui Duan, Sandro Yong, Amit Vasanji, Michael Kinter, Russell Desnoyer, Sadashiva S Karnik
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155198 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0052689.].
Externí odkaz:
https://doaj.org/article/26feb6fb04e244c1949799640ae9ffe4
Autor:
Anushree Bhatnagar, Hamiyet Unal, Rajaganapathi Jagannathan, Suma Kaveti, Zhong-Hui Duan, Sandro Yong, Amit Vasanji, Michael Kinter, Russell Desnoyer, Sadashiva S Karnik
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52689 (2013)
Heterotrimeric G-protein signal transduction initiated by G-protein-coupled receptors (GPCRs) in the plasma membrane is thought to propagate through protein-protein interactions of subunits, Gα and Gβγ in the cytosol. In this study, we show novel
Externí odkaz:
https://doaj.org/article/76eedc5b0eba4213a1e4347a02ddfe06
Autor:
Rajaganapathi Jagannathan, Suma Kaveti, Russell W Desnoyer, Belinda Willard, Michael Kinter, Sadashiva S Karnik
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12552 (2010)
Chronic activation of angiotensin II (AngII) type 1 receptor (AT(1)R), a prototypical G protein-coupled receptor (GPCR) induces gene regulatory stress which is responsible for phenotypic modulation of target cells. The AT(1)R-selective drugs reverse
Externí odkaz:
https://doaj.org/article/1cb7ddca70b748c7819f1c9bbc8186a3
Autor:
JEONGKYUNG LEE, RUYA LIU, FENG LI, VINNY NEGI, RAJAGANAPATHI JAGANNATHAN, MARK HUISING, KE MA, BEN SHIH, MOUSUMI MOULIK, VIJAY YECHOOR
Publikováno v:
Diabetes. 71
The transcriptional factor, Tead1, mediates the transcriptional output of the Hippo pathway. Tead1 activates the transcription of downstream genes including many cell cycle promoting genes that lead to cell proliferation in many tissues, but its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103158e264ba148c96fbb4eb84b219e6
https://doi.org/10.2337/db22-250-lb
https://doi.org/10.2337/db22-250-lb
Autor:
Ping Yang, Rajaganapathi Jagannathan, Jeongkyung Lee, Lingfei Sun, Eliana Melissa Perez-Garcia, Ruya Liu, Sruti Shiva, Vinny Negi, Mousumi Moulik, Feng Li, Vijay Yechoor
Publikováno v:
Am J Physiol Heart Circ Physiol
Mitochondrial dysfunction occurs in most forms of heart failure. We have previously reported that Tead1, the transcriptional effector of Hippo pathway, is critical for maintaining adult cardiomyocyte function, and its deletion in adult heart results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13391c6523c60e18e4171739019b804b
https://doi.org/10.1152/ajpheart.00732.2019
https://doi.org/10.1152/ajpheart.00732.2019
Akademický článek
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Autor:
Rajaganapathi Jagannathan, Abby D. Harold, Karen E. Hayes, Ivan Martinez, Saleem A. Khan, Jamie A. Barr, Paul R. Lockman, Tayvia Brownmiller
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
High-risk human papillomavirus (HPV) infection is one of the first events in the process of carcinogenesis in cervical and head and neck cancers. The expression of the viral oncoproteins E6 and E7 are essential in this process by inactivating the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e1fb63aed086a9ab665a1127217847
https://doi.org/10.1038/s41598-019-40094-8
https://doi.org/10.1038/s41598-019-40094-8