Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Raja G, Khalifah"'
Type IV collagen alpha1-alpha6 chains have important roles in the assembly of basement membranes and are implicated in the pathogenesis of Goodpasture syndrome, an autoimmune disorder, and Alport syndrome, a hereditary renal disease. We report compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca5d16f139e8d54fe680112d2018db2
https://ora.ox.ac.uk/objects/uuid:dac858b5-4e91-47ae-955a-97b548817dc1
https://ora.ox.ac.uk/objects/uuid:dac858b5-4e91-47ae-955a-97b548817dc1
Publikováno v:
Biochemical and Biophysical Research Communications. 257:251-258
The present review focuses on the background and progress that led to discovery of specific inhibition of post-Amadori formation of advanced glycation end products, or AGEs. The "classic" or Hodge pathway begins with glucose condensation with amino g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a86d1135af3fe909c2920831f426f5
https://doi.org/10.1006/bbrc.1999.0371
https://doi.org/10.1006/bbrc.1999.0371
Autor:
Julie K. Hudson, Billy G. Hudson, Charles F. Shield, Hideaki Nagase, Joni D. Mott, Raja G. Khalifah
Publikováno v:
Kidney International. 52:1302-1312
Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility. The glomerular basement membrane (GBM) is damaged in diabetes through complex mechanisms that are not fully understood. Prominent among them is nonenzymatic prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c5bda62561ab6629fe2c18e441c43d
https://doi.org/10.1038/ki.1997.455
https://doi.org/10.1038/ki.1997.455
Publikováno v:
Journal of Biological Chemistry. 272:5430-5437
Nonenzymatic protein glycation (Maillard reaction) leads to heterogeneous, toxic, and antigenic advanced glycation end products ("AGEs") and reactive precursors that have been implicated in the pathogenesis of diabetes, Alzheimer's disease, and norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3392f69849d66534ced6cddac95b2a14
https://doi.org/10.1074/jbc.272.9.5430
https://doi.org/10.1074/jbc.272.9.5430
Publikováno v:
Biochemistry. 35:4645-4654
Nonenzymatic glycation (Maillard reaction) of long-lived proteins is a major contributor to the pathology of diabetes and possibly aging and Alzheimer's disease. We report here kinetic studies of the glycation of the model protein ribonuclease A by g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cb163c3ab85a4e1a74b08088a33857
https://doi.org/10.1021/bi9525942
https://doi.org/10.1021/bi9525942
Publikováno v:
Biochemistry. 32:3058-3066
The visible spectrum of Co(II)-substituted human carbonic anhydrase I (HCA I) complexed with the unique CO2-competitive inhibitor imidazole undergoes a marked alkaline intensification, with a midpoint near pH 8 [Bauer, R., Limkilde, P., & Johansen, J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e11baa31e06b00a2f10febe30fa571d
https://doi.org/10.1021/bi00063a017
https://doi.org/10.1021/bi00063a017
Autor:
Raja G. Khalifah, J S Parr
Publikováno v:
Journal of Biological Chemistry. 267:25044-25050
We previously showed that the zinc metalloenzyme carbonic anhydrases (CA I and II isozymes) bind "neutral" amides and related compounds as anions through coordination of their deprotonated amide nitrogen to the active site zinc (Rogers, J. I., Mukher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb47bbe67974ee6d106e602b9e922fcd
https://doi.org/10.1016/s0021-9258(19)74003-4
https://doi.org/10.1016/s0021-9258(19)74003-4
Autor:
Paul A, Voziyan, Raja G, Khalifah, Christophe, Thibaudeau, Alaattin, Yildiz, Jaison, Jacob, Anthony S, Serianni, Billy G, Hudson
Publikováno v:
The Journal of biological chemistry. 278(47)
Hyperglycemic conditions of diabetes accelerate protein modifications by glucose leading to the accumulation of advanced glycation end-products (AGEs). We have investigated the conversion of protein-Amadori intermediate to protein-AGE and the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c311c8d68c5701ad3ddb4148b3735bd
https://pubmed.ncbi.nlm.nih.gov/12975371
https://pubmed.ncbi.nlm.nih.gov/12975371
Autor:
Mark E. Williams, Chwei-Shiun Yang, Kuan-Yu Hung, Areti Makedou, L. Ferder, Igor Rudenco, Kimihiko Yanase, M. Ferder, Satoshi Morimoto, Daniela Corna, Rajiv Agarwal, Kali Makedou, Janet B. McGill, Masayo Aizawa, Katsumi Eguchi, F. Inserra, Katsunori Sawada, Colin E. Murdoch, Yukiko Hasuike, Pantelis Sarafidis, Giuseppe Remuzzi, Chun-Fu Lai, Andrea Remuzzi, Fabio Sangalli, Kunihiro Ichinose, Thorsten P. Degenhardt, Toshiji Iwasaka, Eiji Kawasaki, Takahiro Kuragano, Dario Cattaneo, Ariela Benigni, Kei Maki, Hsueh-Fang Chuang, Shigeo Yamamoto, Rong Li, Vasilios Raptis, Fabiola Carrara, Gian Vico Melzi d’Eril, Ching-Jyh Shiah, Norberto Perico, Yuefang Huang, Maurizio Gallieni, Robert J. Schotzinger, Chung-Hsin Chang, Kwan-Dun Wu, Yih-Ron Lien, Flavio Gaspari, Chia-Sheng Lu, Fang Wang, Xueqing Yu, Ming-Shiou Wu, Min Zhang, Tun-Jun Tsai, Reiko Hata, Dimirios M. Grekas, Lili Zhang, Yingjie Liang, W. Kline Bolton, Yoshimi Takai, Shou-Shang Chiang, Pavlos Malindretos, Takeshi Nakanishi, Niansheng Yang, Rintarou Moriguchi, Yu-Sen Peng, Andrea Galassi, Ajay M. Shah, Maria Luisa Biondi, Raja G. Khalifah, Yutaka Yano, Alex Sirker, E.M.V. de Cavanagh, Jun Miyoshi, Kouji Miyagawa, Wang-Yu Chen, Mario Cozzolino, Chih-Ching Yang, Tsuyoshi Tanimoto, Carla Zoja, Rui Zhang, Yu-Ting Wang, Masaaki Izumi, Diego Brancaccio, Mingqian Luo
Publikováno v:
American Journal of Nephrology. 27:665-666
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd8465f52bda450f210a8a884b87063
https://doi.org/10.1159/000110538
https://doi.org/10.1159/000110538
Autor:
Robert J. Schotzinger, Shou-Shang Chiang, Yingjie Liang, Tun-Jun Tsai, Janet B. McGill, Masayo Aizawa, Hsueh-Fang Chuang, Areti Makedou, L. Ferder, Jun Miyoshi, F. Inserra, Colin E. Murdoch, Katsunori Sawada, Shigeo Yamamoto, Kimihiko Yanase, Chih-Ching Yang, Mark E. Williams, Eiji Kawasaki, Ariela Benigni, Rajiv Agarwal, Niansheng Yang, Carla Zoja, Fabio Sangalli, Kuan-Yu Hung, Rintarou Moriguchi, Flavio Gaspari, Katsumi Eguchi, Raja G. Khalifah, M. Ferder, Pavlos Malindretos, Masaaki Izumi, Fabiola Carrara, Min Zhang, Daniela Corna, Mingqian Luo, Tsuyoshi Tanimoto, Chwei-Shiun Yang, Yu-Sen Peng, Yukiko Hasuike, Alex Sirker, W. Kline Bolton, Takeshi Nakanishi, Ajay M. Shah, Yoshimi Takai, Kouji Miyagawa, Kali Makedou, Kei Maki, Dario Cattaneo, Thorsten P. Degenhardt, Chun-Fu Lai, Yuefang Huang, Diego Brancaccio, Vasilios Raptis, Mario Cozzolino, Toshiji Iwasaka, Maurizio Gallieni, Pantelis Sarafidis, Giuseppe Remuzzi, Gian Vico Melzi d’Eril, Reiko Hata, Andrea Remuzzi, Maria Luisa Biondi, Yih-Ron Lien, Kunihiro Ichinose, Ming-Shiou Wu, Chung-Hsin Chang, Xueqing Yu, Takahiro Kuragano, Andrea Galassi, Dimirios M. Grekas, Rong Li, Igor Rudenco, Satoshi Morimoto, Ching-Jyh Shiah, Norberto Perico, Kwan-Dun Wu, Rui Zhang, Chia-Sheng Lu, Yu-Ting Wang, E.M.V. de Cavanagh, Fang Wang, Lili Zhang, Wang-Yu Chen, Yutaka Yano
Publikováno v:
American Journal of Nephrology. 27:661-662
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b06258d47109212fd7b74bed9a904b10
https://doi.org/10.1159/000110536
https://doi.org/10.1159/000110536