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pro vyhledávání: '"Raj Schneider"'
Autor:
Raj Schneider, Jana Kerkhoff, Andreas Danzer, Amelie Mattusch, Andrijan Ohmann, Markus Thommes, Gabriele Sadowski
Publikováno v:
International Journal of Pharmaceutics: X, Vol 2, Iss , Pp 100063- (2020)
Supersaturation profiles of amorphous indomethacin in aqueous solution containing 0.4 wt% and 4 wt% of isopropanol were predicted by combining separately-determined kinetics for dissolution, solution crystallization, and solid-state transformation. T
Externí odkaz:
https://doaj.org/article/0f8b03284ad04b0893bfb00f559a8721
Publikováno v:
International Journal of Pharmaceutics. 582:119317
Polymeric excipients have proven to be beneficial in stabilizing supersaturated solutions of poorly soluble active pharmaceutical ingredients (APIs). They are therefore considered an important tool in improving oral bioavailability of such APIs. To b