Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Raj S. Mitra"'
Autor:
Raj. S. Mitra, Mary A. Benedict, Dalong Qian, Kimberly E. Foreman, Daryoush Ekhterae, Brian J. Nickoloff, Gabriel Nuñez
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 437-445 (2001)
Kaposi's sarcoma (KS) is the most common tumor affecting AIDS patients with over 20% of these patients afflicted by this disease. Previous studies have demonstrated that KS tumor cells predominantly express the prosurvival protein Bcl-XL compared wit
Externí odkaz:
https://doaj.org/article/44e849354f90457f91e994585607b5bc
Autor:
Mitsuo Goto, Thomas E. Carey, Carol R. Bradford, Kitrina G. Cordell, Jeremy M. G. Taylor, Nisha J. D'Silva, Keith L. Kirkwood, Julia S. Lee, Mark E. Prince, Raj S. Mitra, Quintin Pan, Diana Maldonado
Publikováno v:
Cancer Research. 68:3959-3969
The objective of the current study was to investigate the effects of Rap1GAP on invasion and progression of head and neck squamous cell carcinoma (SCC) and the role of matrix metalloproteinase (MMP) 9 and MMP2 in this process. Rap1GAP functions by sw
Autor:
Derek D. Coatney, Keith L. Kirkwood, Fei Li, Bradley S. Henson, Raj S. Mitra, Thomas E. Carey, Nisha J. D'Silva
Publikováno v:
Journal of Oral Pathology & Medicine. 36:363-370
The molecular investigation of head and neck cancer targets requires the utilization and optimization of established animal models to characterize the effects of gene transcription and protein expression on invasion and metastasis. Floor-of-the-mouth
Autor:
Tetsuya Ogawa, Ikuo Hyodo, Yasuhisa Hasegawa, Raj S. Mitra, Nisha J. D'Silva, Thomas E. Carey, Mitsuo Goto, Brent B. Ward, Akihiro Terada
Publikováno v:
Toukeibu Gan. 33:232-237
Autor:
P. Anil Kumar, Julia S.-J. Lee, Zhaocheng Zhang, Raj S. Mitra, Nabanita S. Datta, Nisha J. D'Silva, Bradley S. Henson, Thomas E. Carey, Laurie K. McCauley
Publikováno v:
The American Journal of Pathology. 168:585-596
Rap1, a growth regulatory protein that is strongly expressed in human squamous cell carcinoma (SCC), is inactivated by rap1GAP. Recent evidence in normal rat cells suggests that rap1GAP regulates proliferation. The objective of the current study was
Autor:
David M. Kurnit, Zhaocheng Zhang, Thomas E. Carey, Raj S. Mitra, Nisha J. D'Silva, Bradley S. Henson
Publikováno v:
Oncogene. 22:6243-6256
We recently showed that rap1 regulates growth and proliferation in normal keratinocytes, which provoked us to investigate its expression and regulation in malignant cells. Rap1 is variably expressed in whole cell lysates of squamous cell carcinoma (S
Publikováno v:
Clinical Immunology and Immunopathology. 78:172-179
Prior to the AIDS epidemic, Kaposi's sarcoma (KS) was a rare neoplasm. However, in the context of immunosuppression, cutaneous KS lesions more frequently develop and express various surface molecules recognized by T cells such as intercellular adhesi
Publikováno v:
Journal of Investigative Dermatology. 103(4):569-575
Keratinocyte intercellular adhesion molecule-1 (ICAM-1) is important in mediating retention of T cells within the epidermal compartment. To determine if antisense oligonucleotides designed to hybridize to various ICAM-1 mRNA regions could selectively
Publikováno v:
Journal of Cellular Physiology. 156:348-357
Early cellular and molecular events in inflamed skin include the active participation of epidermal keratinocytes (KCs) and dermal mast cells which can produce diffusible mediators such as tumor necrosis factor-alpha (TNF-alpha), histamine, and urocan
Publikováno v:
Journal of Investigative Dermatology. 98(1):92-95
T lymphocytes infiltrate the epidermis and follicular epithelium adhering to keratinocytes within hours following induction of cutaneous inflammation. to determine if the physical binding interaction between a T cell and keratinocyte induces transmis