Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Raj R Rao"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120782 (2015)
Cyclin Dependent Kinase-2 Associated Protein-1 (CDK2AP1) is known to be a tumor suppressor that plays a role in cell cycle regulation by sequestering monomeric CDK2, and targeting it for proteolysis. A reduction of CDK2AP1 expression is considered to
Externí odkaz:
https://doaj.org/article/18836e35f1e441f9ac7f51b4655dfa61
Autor:
Mahesh C Dodla, Amber Young, Alison Venable, Kowser Hasneen, Raj R Rao, David W Machacek, Steven L Stice
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23266 (2011)
Human embryonic stem cells (hESCs) and their differentiated progeny allow for investigation of important changes/events during normal embryonic development. Currently most of the research is focused on proteinacous changes occurring as a result of di
Externí odkaz:
https://doaj.org/article/acc1ac667cf747b898b5697a82dc509c
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10001 (2010)
The DNA double-strand break (DSB) is the most toxic form of DNA damage. Studies aimed at characterizing DNA repair during development suggest that homologous recombination repair (HRR) is more critical in pluripotent cells compared to differentiated
Externí odkaz:
https://doaj.org/article/59bf2534616a45fdbe5647f0a7248012
Autor:
Ishita Tandon, Vitali Maldonado, Megan Wilkerson, Amanda Walls, Raj R. Rao, Mostafa Elsaadany
Publikováno v:
Frontiers in Medical Technology, Vol 6 (2024)
IntroductionImmersive virtual reality (VR) based laboratory demonstrations have been gaining traction in STEM education as they can provide virtual hands-on experience. VR can also facilitate experiential and visual learning and enhanced retention. H
Externí odkaz:
https://doaj.org/article/57f2ff98e35c4389bda8cbbd0f468939
Autor:
Fibi Meshrkey, Kelly M. Scheulin, Christopher M. Littlejohn, Joshua Stabach, Bibhuti Saikia, Vedant Thorat, Yimin Huang, Thomas LaFramboise, Edward J. Lesnefsky, Raj R. Rao, Franklin D. West, Shilpa Iyer
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Background Human mitochondrial DNA mutations are associated with common to rare mitochondrial disorders, which are multisystemic with complex clinical pathologies. The pathologies of these diseases are poorly understood and have no FDA-appro
Externí odkaz:
https://doaj.org/article/da7822bfd6444abb9d4aa5595fa3c1d7
Autor:
Vitali V. Maldonado, Neel H. Patel, Emma E. Smith, C. Lowry Barnes, Michael P. Gustafson, Raj R. Rao, Rebekah M. Samsonraj
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-22 (2023)
Abstract Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous potential in regenerative medicine. With their immunomodulatory and regenerative properties, MSCs have numerous applications within the clinical sector. MS
Externí odkaz:
https://doaj.org/article/91522a5e8e264204a0e3c535f236b046
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-16 (2023)
Abstract Background Recent advancements in additive manufacturing have made 3D design a desirable skill in combating the historically slow development of biomedical products. Due to the broad applicability of additive manufacturing to biomedical engi
Externí odkaz:
https://doaj.org/article/30d1bd1e48714173bbc4e8a3a5e0b9b2
Autor:
Mahsa Haseli, David A. Castilla-Casadiego, Luis Pinzon-Herrera, Alexander Hillsley, Katherine A. Miranda-Munoz, Srikanth Sivaraman, Adrianne M. Rosales, Raj R. Rao, Jorge Almodovar
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100194- (2022)
Human mesenchymal stromal cells (hMSCs) are multipotent cells that have been proposed for cell therapies due to their immunosuppressive capacity that can be enhanced in the presence of interferon-gamma (IFN-γ). In this study, multilayers of heparin
Externí odkaz:
https://doaj.org/article/1a6b4057581f4da9b34253167a16dd13
Publikováno v:
Stem Cell Research, Vol 57, Iss , Pp 102572- (2021)
Mitochondria are dynamic organelles with wide range of morphologies contributing to regulating different signaling pathways and several cellular functions. Leigh syndrome (LS) is a classic pediatric mitochondrial disorder characterized by complex and
Externí odkaz:
https://doaj.org/article/e8fef2adc2474902926b7d588bb5b545
Publikováno v:
Tissue Engineering Part B: Reviews. 29:1-9
Cardiovascular diseases are responsible for 31% of global deaths and are considered the main cause of death and disability worldwide. Stem cells from various sources have become attractive options for a range of cell-based therapies for smooth muscle