Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Raj Pranap Arun"'
Autor:
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 91-112 (2024)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes. To investigate the mechanism of ALDH1A3‐med
Externí odkaz:
https://doaj.org/article/3963ad169532432cb23f181c5b3a6969
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4102 (2024)
Cancer stem cells (CSCs) represent a subpopulation within tumors that promote cancer progression, metastasis, and recurrence due to their self-renewal capacity and resistance to conventional therapies. CSC-specific markers and signaling pathways high
Externí odkaz:
https://doaj.org/article/0bb97474ec694a6e9507fd1273b171b4
Autor:
Meghan E. McLean, Maya R. MacLean, Hannah F. Cahill, Raj Pranap Arun, Olivia L. Walker, Marie-Claire D. Wasson, Wasundara Fernando, Jaganathan Venkatesh, Paola Marcato
Publikováno v:
Cancers, Vol 15, Iss 2, p 492 (2023)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is one of 19 ALDH enzymes expressed in humans, and it is critical in the production of hormone receptor ligand retinoic acid (RA). We review the role of ALDH1A3 in normal physiology, its identification as a cancer
Externí odkaz:
https://doaj.org/article/42f3a6f9b55a4cf88f69d14bd0963dbf
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 1, Iss , Pp 100004- (2021)
Cancer stem cells (CSCs) present in tumours are the primary cause of cancer recurrence and mediates resistance against therapeutic intervention. CSC properties like epithelial-to-mesenchymal transition (EMT) and cancer stemness lead to metastasis, qu
Externí odkaz:
https://doaj.org/article/ada442579fcf4d929d6ad45a6c354756
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 651 (2022)
The regulatory and functional roles of non-coding RNAs are increasingly demonstrated as critical in cancer. Among non-coding RNAs, microRNAs (miRNAs) are the most well-studied with direct regulation of biological signals through post-transcriptional
Externí odkaz:
https://doaj.org/article/05438e5e17b84a849a2d4172e6cb2dce
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Gravity is a major physical factor determining the stress and strain around cells. Both in space experiments and ground simulation, change in gravity impacts the viability and function of various types of cells as well as in vivo conditions.
Externí odkaz:
https://doaj.org/article/9ecf14fcf5bf41daac8f7b01f633b923
Publikováno v:
Methods in cell biology. 171
The heterogeneity of breast tumors is a major factor in the development, progression, and therapeutic response of breast cancer. In terms of therapy resistance, a subset of tumor cells commonly referred to as cancer stem cells (CSCs) or tumor initiat
Publikováno v:
Methods in Cell Biology ISBN: 9780323900188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e96cfba0321172b8a372cf91e11a680
https://doi.org/10.1016/bs.mcb.2022.04.006
https://doi.org/10.1016/bs.mcb.2022.04.006