Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Raj P Kapur"'
Autor:
Jennifer Tisoncik-Go, Caleb Stokes, Leanne S. Whitmore, Daniel J. Newhouse, Kathleen Voss, Andrew Gustin, Cheng-Jung Sung, Elise Smith, Jennifer Stencel-Baerenwald, Edward Parker, Jessica M. Snyder, Dennis W. Shaw, Lakshmi Rajagopal, Raj P. Kapur, Kristina M. Adams Waldorf, Michael Gale
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Zika virus (ZikV) infection during pregnancy can cause congenital Zika syndrome (CZS) and neurodevelopmental delay in infants, of which the pathogenesis remains poorly understood. We utilize an established female pigtail macaque maternal-to-
Externí odkaz:
https://doaj.org/article/5738fe70556843ec9ca7594574c778e6
Autor:
Jeroen P Vanderhoeven, Craig J Bierle, Raj P Kapur, Ryan M McAdams, Richard P Beyer, Theo K Bammler, Federico M Farin, Aasthaa Bansal, Min Spencer, Mei Deng, Michael G Gravett, Craig E Rubens, Lakshmi Rajagopal, Kristina M Adams Waldorf
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003920 (2014)
Early events leading to intrauterine infection remain poorly defined, but may hold the key to preventing preterm delivery. To determine molecular pathways within fetal membranes (chorioamnion) associated with early choriodecidual infection that may p
Externí odkaz:
https://doaj.org/article/553e5f495d3046b0b24731b494724422
Autor:
Ryan M McAdams, Jeroen Vanderhoeven, Richard P Beyer, Theo K Bammler, Federico M Farin, H Denny Liggitt, Raj P Kapur, Michael G Gravett, Craig E Rubens, Kristina M Adams Waldorf
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46863 (2012)
Intrauterine exposure to amniotic fluid (AF) cytokines is thought to predispose to bronchopulmonary dysplasia (BPD). We evaluated the effects of GBS exposure on RNA expression in fetal lung tissue to determine early molecular pathways associated with
Externí odkaz:
https://doaj.org/article/28eb5e47ddbc4ba2b272e8fefa22ecac
Autor:
Kristina M Adams Waldorf, Michael G Gravett, Ryan M McAdams, Louis J Paolella, G Michael Gough, David J Carl, Aasthaa Bansal, H Denny Liggitt, Raj P Kapur, Frederick B Reitz, Craig E Rubens
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28972 (2011)
Early events leading to intrauterine infection and fetal lung injury remain poorly defined, but may hold the key to preventing neonatal and adult chronic lung disease. Our objective was to establish a nonhuman primate model of an early stage of chori
Externí odkaz:
https://doaj.org/article/f77f872a70854e699bede7e65cf79ebf
Autor:
Gygeria Manuel, Michelle Coleman, Austyn S. Orvis, Jeff Munson, Amanda Li, Raj P. Kapur, Miranda Li, Edmunda Li, Blair Armistead, Lakshmi Rajagopal, Kristina M. Adams Waldorf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
BackgroundPreterm birth is a leading cause of neonatal mortality, which is often complicated by intrauterine infection and inflammation. We have established a nonhuman primate model of Group B Streptococcus (GBS, Streptococcus agalactiae) infection-a
Externí odkaz:
https://doaj.org/article/a997645dc6e54b4a9ffa9d49fece1780
Publikováno v:
Informatics in Medicine Unlocked, Vol 23, Iss , Pp 100518- (2021)
Hirschsprung's disease (HD) is a birth defect which is diagnosed and managed by multiple medical specialties such as pediatric gastroenterology, surgery, radiology, and pathology. HD is characterized by absence of ganglion cells in the distal intesti
Externí odkaz:
https://doaj.org/article/5eeb123e60464e8aae0cb3b0e64366fd
Autor:
Raj P. Kapur
Publikováno v:
Pediatric and Developmental Pathology. 26:39-51
Background: Pathogenic mutations in the smooth muscle myosin heavy chain gene, MYH11, cause megacystis megacolon intestinal hypoperistalsis syndrome and other forms of chronic intestinal pseudo-obstruction. Evaluation of intestinal tissues from affec
Publikováno v:
Pediatric Surgery International. 38:1989-1996
Background Hirschsprung disease is one of the most common congenital anomalies that affects colorectal function. Rectal biopsy demonstrating the absence of ganglion cells in the affected bowel is the gold standard for diagnosis. Suction and incisiona
Publikováno v:
Pediatric and Developmental Pathology. 25:581-597
Background Dominant gamma-smooth muscle actin gene ( ACTG2) variants cause clinically diverse forms of visceral myopathy. Many patients undergo intestinal resection or biopsy before identification of their genetic defect. The pathology of ACTG2-varia
Autor:
Brahm Coler, Tsung-Yen Wu, Lindsey Carlson, Nicole Burd, Jeff Munson, Matthew Dacanay, Orlando Cervantes, Sean Esplin, Raj P. Kapur, Helen Feltovich, Kristina M. Adams Waldorf
Publikováno v:
American Journal of Obstetrics and Gynecology. 228:463.e1-463.e20
COVID-19 is caused by the SARS-CoV-2 virus and is associated with critical illness requiring hospitalization, maternal mortality, stillbirth, and preterm birth. SARS-CoV-2 has been shown to induce placental pathology. However, substantial gaps exist