Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Raj Kumar Pandita"'
Autor:
Karl-Erik Andersson, Thomas Stöhr, Raj Kumar Pandita, Alexander Breidenbach, Peter Ney, Donald Newgreen
Publikováno v:
BJU International. 101:1036-1042
OBJECTIVE To investigate the primary pharmacology of fesoterodine (a novel antimuscarinic drug developed for treating overactive bladder) and SPM 7605 (its active metabolite, considered to be the main pharmacologically active principle of fesoterodin
Autor:
Raj Kumar Pandita, Karl-Erik Andersson, Margaret Warner, Petter Hedlund, Jan-Åke Gustafsson, Annette Schröder
Publikováno v:
Journal of Urology. 170:1013-1016
The influence of estrogen on bladder function has been the subject of several experimental and clinical studies. In addition to the well-known estrogen receptor (ER)alpha, recently the ER subtype ERbeta was discovered. We investigated potential chang
Publikováno v:
British Journal of Pharmacology. 139:741-748
(±)-Tramadol, a widely used analgesic, is a racemate stimulating opioid receptors and inhibiting reuptake of noradrenaline and serotonin, that is, pharmacological principles previously shown to influence rat micturition. We studied both (±)-tramado
Autor:
Karl-Erik Andersson, Raj Kumar Pandita
Publikováno v:
Journal of Urology. 168:1230-1234
Adenosine triphosphate (ATP) (Sigma Chemical Co., St. Louis, Missouri) is known to contract animal as well as human detrusor muscle and recent investigations have shown an involvement of ligand gated purinergic-1 receptors in detrusor contraction. In
Publikováno v:
The Journal of Urology. :1385-1389
Purpose: To develop a model for cystometric study of bladder function in the awake mouse, and to characterize urodynamically and immunohistochemically the non-obstructed and infravesically obstructed mouse bladder.Materials and Methods: Non-obstructe
Autor:
Karl-Erik Andersson, Raj Kumar Pandita, Alexander Pfeifer, Marianne Ahmad, Reinhard Fässler, Katarina Persson, Attila Aszódi
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 279:R1112-R1120
Nitric oxide (NO)-mediated smooth muscle relaxation is mediated by cGMP through activation of cGMP-dependent protein kinase I (cGKI). We studied the importance of cGKI for lower urinary tract function in mice lacking the gene for cGKI (cGKI−/−) a
Publikováno v:
Journal of Urology. 164:545-550
Purpose: To investigate whether intravesical oxyhemoglobin, a nitric oxide scavenger, changes bladder activity in normal rats.Materials and Methods: Oxyhemoglobin was given intravesically at different concentrations to conscious, female Sprague-Dawle
Publikováno v:
The Prostate. 35:102-108
Testosterone-induced prostatic growth in the rat causes bladder overactivity unrelated to detrusor hypertrophy
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R1186-R1192
The mechanisms and mediators of hypertrophic growth secondary to infravesical urinary outflow obstruction are unknown. The renin-angiotensin system has been implicated in vascular and cardiac hypertrophy, but the involvement of angiotensin II (ANG II
Autor:
Peter, Ney, Raj Kumar, Pandita, Donald T, Newgreen, Alexander, Breidenbach, Thomas, Stöhr, Karl-Erik, Andersson
Publikováno v:
BJU international. 101(8)
To investigate the primary pharmacology of fesoterodine (a novel antimuscarinic drug developed for treating overactive bladder) and SPM 7605 (its active metabolite, considered to be the main pharmacologically active principle of fesoterodine in man)