Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Raj K Rajakulasingam"'
Panton–Valentine leucocidin Staphylococcus aureus necrotising pneumonia in a clinically well patient
Publikováno v:
British Journal of Hospital Medicine. 84:1-4
Publikováno v:
The Lancet Respiratory Medicine
The Lancet. Respiratory Medicine
The Lancet. Respiratory Medicine
The management of the COVID-19 pandemic is hampered by long delays associated with centralised laboratory PCR testing. In hospitals, these delays lead to poor patient flow and nosocomial transmission. Rapid, accurate tests are therefore urgently need
Autor:
Mamidipudi Thirumala Krishna, Raj K Rajakulasingam, Shuaib Nasser, Andrew Clark, Stephen R. Durham, Pia A. J. Huber, N Farah
Publikováno v:
Clinical & Experimental Allergy. 48:89-92
Allergen specific immunotherapy (SIT) alleviates symptoms, improves health-related quality of life and alters the natural course of the disease in patients suffering from allergic rhinitis. It is currently delivered in the UK National Health Service
Autor:
Chris Griffiths, Richard Hooper, Aklak Choudhury, Claire L. Greiller, Christopher Corrigan, David A. Jolliffe, Wai Yee James, Elina Hyppönen, Angshu Bhowmik, David E. Simcock, Kamrul Islam, Peter Timms, Neil Barnes, Raj K Rajakulasingam, Robert Walton, Adrian R. Martineau
Publikováno v:
Jolliffe, D A, James, W Y, Hooper, R L, Barnes, N C, Greiller, C L, Islam, K, Bhowmik, A, Timms, P M, Rajakulasingam, R K, Choudhury, A B, Simcock, D E, Hyppönen, E, Walton, R T, Corrigan, C J, Griffiths, C J & Martineau, A R 2017, ' Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK ', Journal of Steroid Biochemistry and Molecular Biology . https://doi.org/10.1016/j.jsbmb.2017.01.019
Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease (COPD), yet a comprehensive analysis of environmental and genetic determinants of serum 25-hydroxyvitamin D (25[OH]D) concentration in patients with this condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3355237f23719ec03aa66e69bcfa3743
http://hdl.handle.net/10044/1/45813
http://hdl.handle.net/10044/1/45813
Autor:
Beverley MacLaughlin, Aklak Choudhury, Kate Kilpin, Christopher Corrigan, Adrian R. Martineau, Claire L. Greiller, Peter Timms, Chris Griffiths, Richard Hooper, Neil Barnes, Raj K Rajakulasingam, Robert Walton, Elina Hyppönen, David A. Jolliffe, Angshu Bhowmik, David E. Simcock
Publikováno v:
Jolliffe, D A, Kilpin, K, MacLaughlin, B D, Greiller, C L, Hooper, R L, Barnes, N C, Timms, P M, Rajakulasingam, R K, Bhowmik, A, Choudhury, A B, Simcock, D E, Hyppönen, E, Corrigan, C J, Walton, R T, Griffiths, C J & Martineau, A R 2016, ' Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK ', Journal of Steroid Biochemistry and Molecular Biology . https://doi.org/10.1016/j.jsbmb.2016.11.004
Vitamin D deficiency is common in children with asthma, and it associates with poor asthma control, reduced forced expiratory volume in one second (FEV1) and increased requirement for inhaled corticosteroids (ICS). Cross-sectional studies investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1097482740278a2f86ef8c76e3c0dd9d
https://kclpure.kcl.ac.uk/ws/files/58981506/1_s2.0_S0960076016303004_main.pdf
https://kclpure.kcl.ac.uk/ws/files/58981506/1_s2.0_S0960076016303004_main.pdf
Autor:
Christopher Corrigan, Line Ohm-Laursen, S. Ying, Yih-Chih Chan, Andrew Menzies-Gow, Clare Thomas, Shih-Ying Wu, Prathap Pillai, Hannah J. Gould, Raj K Rajakulasingam, Stephen R. Durham
Publikováno v:
Pillai, P, Chan, Y-C, Wu, S-Y, Ohm-Laursen, L, Thomas, C, Durham, S R, Menzies-Gow, A, Rajakulasingam, R K, Ying, S, Gould, H J & Corrigan, C J 2016, ' Omalizumab reduces bronchial mucosal IgE and improves lung function in non-atopic asthma ', European Respiratory Journal . https://doi.org/10.1183/13993003.01501-2015
Omalizumab therapy of non-atopic asthmatics reduces bronchial mucosal IgE and inflammation and preserves/improves lung function when disease is destabilised by staged withdrawal of therapy.18 symptomatic, non-atopic asthmatics were randomised (1:1) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1969db9545704727371c5eaae6cb3e
https://kclpure.kcl.ac.uk/en/publications/8c98d419-2b93-4576-9326-fbe844a8da8a
https://kclpure.kcl.ac.uk/en/publications/8c98d419-2b93-4576-9326-fbe844a8da8a
Publikováno v:
1.13 Clinical Problems - Other.
Introduction: Despite having national guidelines for the management of SP, there appears to be wide variation in clinical practice in UK hospitals. Aims and objectives: The audit aims to study the initial management of primary (PSP) and secondary (SS
Publikováno v:
5.1 Airway Pharmacology and Treatment.
Background: It has been noted that patients with COPD may be inappropriately prescribed long acting β 2 agonist/inhaled corticosteroid combinations (ICS/LABA). Aims: The GOLD guideline recommends that patients with an FEV 1 of Methods: The exacerbat
Autor:
Aklak Choudhury, Chris Griffiths, Neil Barnes, Christopher Corrigan, Raj K Rajakulasingam, Adrian R. Martineau, Claire L. Greiller, Beverley MacLaughlin, Angshu Bhowmik, David E. Simcock, David A. Jolliffe, Wai Yee James
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Background: New treatments for asthma & COPD may require evaluation in sub-groups with lower airway eosinophilia or neutrophilia. A non-invasive test to identify these phenotypes may reduce unnecessary sputum induction at screening. Aim: To establish
Autor:
Amarjeet Degun, Marion Rowe, David A. Jolliffe, David McLaughlin, Aklak Choudhury, Chris Griffiths, Mark Wilks, Richard Hooper, Peter Timms, Timothy R Venton, Neil Barnes, Zia Sadique, Raj K Rajakulasingam, Angshu Bhowmik, David E. Simcock, Christopher Corrigan, Kamrul Islam, Claire L. Greiller, W Monteiro, Wai Yee James, Catherine M. Hawrylowicz, Adrian R. Martineau
Publikováno v:
The Lancet. Respiratory medicine. 3(2)
Summary Background Patients with chronic obstructive pulmonary disease (COPD) often have vitamin D deficiency, which is associated with increased susceptibility to upper respiratory infection—a major precipitant of exacerbation. Multicentre trials