Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Raj Johal"'
Publikováno v:
BMJ Open Quality, Vol 11, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/541ce56e47fe4652a94179cd76ca859c
Autor:
Thomas W. Claydon, Glen F. Tibbits, Eric Lin, Diana Hunter, Yen May Cheng, Damon Poburko, Raj Johal, Mandy Yip, Ravichandra Venkateshappa, Shoaib Faizi, Kyle E. Simpson
Publikováno v:
Journal of visualized experiments : JoVE. (187)
Clustered regularly interspaced short palindromic repeats (CRISPR) in animal models enable precise genetic manipulation for the study of physiological phenomena. Zebrafish have been used as an effective genetic model to study numerous questions relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3920a0dc585774f0f578f0ec304175bd
https://pubmed.ncbi.nlm.nih.gov/36190280
https://pubmed.ncbi.nlm.nih.gov/36190280
Autor:
ZhaoKai Pang, Ravichandra Venkateshappa, Dominic G. Whittaker, Gary R. Mirams, Valentine Sergeev, Glen F. Tibbits, Thomas W. Claydon, Jacob M Kemp, Raj Johal
Publikováno v:
The Journal of General Physiology
Kemp et al. show that the hERG channel activator RPR260243 restores the repolarizing current of a mutant variant of the channel associated with LQTS2 with little effect on its resurgent current. This drug represents a therapeutic opportunity for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f19ef19ae0d8d9059439829ec3c870
https://pubmed.ncbi.nlm.nih.gov/34398210
https://pubmed.ncbi.nlm.nih.gov/34398210