Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Raj J. Chovatiya"'
Autor:
Raj J. Chovatiya, Annette N. Chiang, Jeffrey L. Brodsky, Corinne Schneider, Brian P. Mead, Samantha L. Bell, Donna M. Huryn, Xiaojiang S. Chen, David A. Fidock, Billy W. Day, Michael G. Klein, Juan Carlos Valderramos, Raghavan Balachandran, Peter Wipf
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:1527-1533
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle. In any organism, Hsp70 chaperones are typ
Autor:
Stefan Werner, Billy W. Day, Guangyu Zhu, Christine M. Wright, James M. Pipas, Nora E. Jameson, Jeffrey L. Brodsky, Peter Wipf, David M. Turner, Donna M. Huryn, Raj J. Chovatiya
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:3291-3301
The Hsp70 molecular chaperones are ATPases that play critical roles in the pathogenesis of many human diseases, including breast cancer. Hsp70 ATP hydrolysis is relatively weak, but is stimulated by J domain-containing proteins. We identified pyrimid