A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer.

Autor: Shimoni-Sebag A; The Benjamin Davidai Department of Radiation Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel. Electronic address: Ariel.Shimoni@sheba.health.gov.il., Abramovich I; Faculty of Medicine, Technion Institute, Efron St. 1, Haifa 3525433, Israel. Electronic address: ifat.a@technion.ac.il., Agranovich B; Faculty of Medicine, Technion Institute, Efron St. 1, Haifa 3525433, Israel. Electronic address: bellakr@technion.ac.il., Massri R; Faculty of Medicine, Technion Institute, Efron St. 1, Haifa 3525433, Israel. Electronic address: rami.masre@gmail.com., Stossel C; Institute of Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel; Tel-Aviv University, Chaim Levanon St. 55, Tel Aviv-Yafo 6997801, Israel. Electronic address: chani.stossel@sheba.health.gov.il., Atias D; Institute of Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel; Tel-Aviv University, Chaim Levanon St. 55, Tel Aviv-Yafo 6997801, Israel. Electronic address: Dikla.Atias@sheba.health.gov.il., Raites-Gurevich M; Institute of Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel. Electronic address: Maria.RaitsesGurevich@sheba.health.gov.il., Yizhak K; Faculty of Medicine, Technion Institute, Efron St. 1, Haifa 3525433, Israel. Electronic address: kyizhak@technion.ac.il., Golan T; Institute of Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel; Tel-Aviv University, Chaim Levanon St. 55, Tel Aviv-Yafo 6997801, Israel. Electronic address: Talia.Golan@sheba.health.gov.il., Gottlieb E; Faculty of Medicine, Technion Institute, Efron St. 1, Haifa 3525433, Israel; The University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA. Electronic address: EGottlieb@mdanderson.org., Lawrence YR; The Benjamin Davidai Department of Radiation Oncology, Sheba Medical Center, Derech Sheba 2, Ramat Gan 5265601, Israel; Tel-Aviv University, Chaim Levanon St. 55, Tel Aviv-Yafo 6997801, Israel; Sidney Kimmel Medical College at Thomas Jefferson University, 4201 Henry Ave, Philadelphia, PA 19144, USA. Electronic address: Yaacov.Lawrence@sheba.health.gov.il.

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2024 Nov 08; Vol. 202, pp. 110606. Date of Electronic Publication: 2024 Nov 08.