Výsledky vyhledávání - "Raissa Alves da Conceição"

Synthesis and in silico and in vitro evaluation of trimethoxy-benzamides designed as anti-prion derivatives

Autor: Carolina F. Goes, Maria Claudia Barbosa, Lucas M. Ascari, Anderson S. Pinheiro, Yraima Cordeiro, Raissa Alves da Conceição, Rodolfo C. Maia, Carolina O. Matos, Natália Ferreira, Marina Amaral Alves, Alessandra Mendonça Teles de Souza, Byron Caughey

Publikováno v: Medicinal Chemistry Research. 28:2128-2141

Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are neurodegenerative disorders which affect mammals, including the human species, and arise after the conversion of the monomeric cellular prion protein (PrPC) into the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15d4aa07930b7416e725b0d1115b9d56
https://doi.org/10.1007/s00044-019-02441-2

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Drugs for the Treatment of Type II Diabetes: A Visit to the Past and a Look to the Future

Autor: Maria Letícia de Castro Barbosa, Paula Nogueira da Silva, Raissa Alves da Conceição

Publikováno v: Revista Virtual de Química. :514-534

O diabetes mellitus consiste em uma sindrome metabolica caracterizada por niveis elevados de glicose sanguinea (hiperglicemia). Atualmente, cerca de 90-95% dos casos de diabetes sao do tipo II, o qual se desenvolve a partir de um quadro inicial de re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::201d0c2a50ab9b3dca52e7c6cb6b9d3d
https://doi.org/10.21577/1984-6835.20170030

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Akademický článek

Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry.

Autor: Barbosa, Maria Letícia de Castro^1,2 (AUTHOR) marialeticia.barbosa@ufjf.br, Pinheiro, Pedro de Sena Murteira^2,3 (AUTHOR) silvafrancolucas@gmail.com, Alves da Conceição, Raissa⁴ (AUTHOR) raissa.conceicao9@gmail.com, Pires, José Ricardo⁵ (AUTHOR) murari@bioqmed.ufrj.br, Franco, Lucas Silva^2,3 (AUTHOR) santanna@ufrrj.br, Sant'Anna, Carlos Mauricio R.^2,3,6 (AUTHOR) ejbarreiro@ccsdecania.ufrj.br, Barreiro, Eliezer J.^2,3 (AUTHOR), Lima, Lídia Moreira^2,3 (AUTHOR) marialeticia.barbosa@ufjf.br

Publikováno v: Molecules. Dec2024, Vol. 29 Issue 24, p6021. 16p.

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NF-κB Signaling Pathway Inhibitors as Anticancer Drug Candidates

Autor: Viviane de Oliveira Freitas Lione, Aline Guerra Manssour Fraga, Raissa Alves da Conceição, Gabriela Cristina de Carvalho Silva, Barbara Dias Camarinha, Maria Letícia de Castro Barbosa, Antonio Gilcler Ferreira Lima, Elisama Azevedo Cardoso

Publikováno v: Anti-cancer agents in medicinal chemistry. 17(4)

Cancer incidence represents an important public health problem worldwide. Nuclear factor kappa B (NF- κB) transcription factor plays a pivotal role in the regulation of genes that control various responses in eukaryotic cells, including proliferatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a43b23f1a19ae6fb8c895366dc71097
https://pubmed.ncbi.nlm.nih.gov/27481554

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