Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Raisa Yrjölä"'
Autor:
Laura E. Vainio, MD, Zoltán Szabó, MSc, Ruizhu Lin, MSc, Johanna Ulvila, PhD, Raisa Yrjölä, MSc, Tarja Alakoski, MSc, Jarkko Piuhola, MD, PhD, Walter J. Koch, PhD, Heikki Ruskoaho, MD, PhD, Shaun D. Fouse, PhD, Todd W. Seeley, PhD, Erhe Gao, MD, PhD, Pierre Signore, PhD, Kenneth E. Lipson, PhD, Johanna Magga, PhD, Risto Kerkelä, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 83-94 (2019)
Summary: Myocardial infarction (MI)−induced cardiac fibrosis attenuates cardiac contractile function, and predisposes to arrhythmias and sudden cardiac death. Expression of connective tissue growth factor (CTGF) is elevated in affected organs in vi
Externí odkaz:
https://doaj.org/article/a4c614fa5d9249b080d2fe33ba0c0e4d
Autor:
Eveliina Halmetoja, Irina Nagy, Zoltan Szabo, Tarja Alakoski, Raisa Yrjölä, Laura Vainio, Eliina Viitavaara, Ruizhu Lin, Lea Rahtu‐Korpela, Seppo Vainio, Risto Kerkelä, Johanna Magga
Publikováno v:
The FASEB Journal. 36
Wnt11 regulates early cardiac development and left ventricular compaction in the heart, but it is not known how Wnt11 regulates postnatal cardiac maturation and response to cardiac stress in the adult heart. We studied cell proliferation/maturation i
Autor:
Zoltan Szabo, Erhe Gao, Raisa Yrjölä, Laura Vainio, Ruizhu Lin, Risto Kerkelä, Walter J. Koch, Jarkko Piuhola, Kenneth E. Lipson, Heikki Ruskoaho, Johanna Magga, Johanna Ulvila, Shaun D. Fouse, Tarja Alakoski, Todd W. Seeley, Pierre E. Signore
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 83-94 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 83-94 (2019)
Visual Abstract
Highlights • To study the role of CTGF in post-MI cardiac repair and LV remodeling, we antagonized the function of CTGF with a mAb. • Treatment of mice with CTGF mAb during post-MI cardiac repair improved survival and resulte
Highlights • To study the role of CTGF in post-MI cardiac repair and LV remodeling, we antagonized the function of CTGF with a mAb. • Treatment of mice with CTGF mAb during post-MI cardiac repair improved survival and resulte
Autor:
Lin Ruizhu, Risto Kerkelä, Raisa Yrjölä, Tarja Alakoski, Zoltan Szabo, Kari Alitalo, Sami Raatikainen, Jarkko Piuhola, Johanna Magga, Manar Elmadani, Ilkka Miinalainen, Pirjo Åström, Olli Tehunen
Publikováno v:
Circulation Research. 125
Aim: Sorafenib (Nexavar) is a multitargeted tyrosine kinase inhibitor that is used for treatment of hepatocellular carcinoma and renal cell carcinoma. Cancer treatment with sorafenib has been reported to be associated with cardiotoxic side effects su
Autor:
Johanna Magga, Johanna Ulvila, Risto Kerkelä, Jonathan D. Licht, Raisa Yrjölä, Tarja Alakoski, Laura Vainio, Zoltan Szabo
Publikováno v:
Basic Research in Cardiology
Sprouty1 (Spry1) is a negative modulator of receptor tyrosine kinase signaling, but its role in cardiomyocyte survival has not been elucidated. The aim of this study was to investigate the potential role of cardiomyocyte Spry1 in cardiac ischemia–r
Autor:
Halmetoja, Eveliina, Nagy, Irina, Szabo, Zoltan, Alakoski, Tarja, Yrjölä, Raisa, Vainio, Laura, Viitavaara, Eliina, Lin, Ruizhu, Rahtu‐Korpela, Lea, Vainio, Seppo, Kerkelä, Risto, Magga, Johanna
Publikováno v:
FASEB Journal; Oct2022, Vol. 36 Issue 10, p1-17, 17p
Autor:
Alakoski, Tarja, Ulvila, Johanna, Yrjölä, Raisa, Vainio, Laura, Magga, Johanna, Szabo, Zoltan, Licht, Jonathan D., Kerkelä, Risto
Publikováno v:
Basic Research in Cardiology; Mar2019, Vol. 114 Issue 2, p1-1, 1p