Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Raisa Persidsky"'
Autor:
Leslie A. Bruch, Jill Faraci, Spring Holter, Jane F. Potter, David Heilman, William H.C. Brown, Kathleen Borgmann, Anuja Ghorpade, VaKara Meyer, Yuri Persidsky, Susan Swindells, Howard E. Gendelman, Robin L. Cotter, Betty Chin, Raisa Persidsky, Li Wu
Publikováno v:
Journal of Neuroimmunology. 163:135-144
Human glia are essential cellular models used for studies of neurodegenerative diseases. Fetal neuroglia are commonly used, as they can be recovered in large quantities and sustained for long periods in culture. However, fetal neuroglia may have limi
Autor:
Raisa Persidsky, Anuja Ghorpade, Jialin C. Zheng, Li Wu, Kathleen Borgmann, Muralidhar S. Deshpande, Courtney N. Schellpeper
Publikováno v:
Neurotoxicity Research. 7:183-192
HIV-1-associated dementia (HAD) is an important complication of HIV-1 infection. Reactive astrogliosis is a key pathological feature in HAD brains and in other central nervous system (CNS) diseases. Activated astroglia may play a critical role in CNS
Autor:
Li Wu, Yuri Persidsky, Kathleen Borgmann, Spring Holter, Anuja Ghorpade, Christine Labenz-Zink, Howard E. Gendelman, Raisa Persidsky, Radhika Suryadevara
Publikováno v:
Glia. 44:47-56
The neuropathogenesis of HIV-1-associated dementia (HAD) revolves around the secretion of toxic molecules from infected and immune-competent mononuclear phagocytes. Astrocyte activation occurs in parallel but limited insights are available for its ro
Publikováno v:
Journal of Neuroimmunology. 141:141-149
Reactive astrogliosis is a prominent pathological feature of HIV-1-associated dementia (HAD). We hypothesized that in HAD, astrocytes activated with proinflammatory stimuli such as IL-1beta express Fas ligand (FasL), a death protein. IL-1beta and HIV
Autor:
Kathleen Borgmann, Anuja Ghorpade, Wei Kou, Li Wu, Namita Sakhuja, Robin Cotter, Ashutosh, Raisa Persidsky
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by amyloid-β (Aβ) deposition in senile plaques colocalized with activated microglia and astrocytes. Recent studies suggest that CXCL8 is involved in the AD pathogenesis. The ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04a4906fef7c226800eb3da1290170e
https://europepmc.org/articles/PMC3236067/
https://europepmc.org/articles/PMC3236067/
Autor:
Timothy F. Walseth, Sugato Banerjee, James D. Eudy, Wei Kou, Li Wu, Namita Sakhuja, Raisa Persidsky, Kathleen Borgmann, Anuja Ghorpade, Muralidhar S. Deshpande, Lynette M. Smith
Publikováno v:
Journal of neuroscience research. 87(10)
Reactive astrogliosis is a key pathological aspect of neuroinflammatory disorders including human immunodeficiency virus type 1 (HIV-1)-associated neurological disease. On the basis of previous data that showedastrocytes activated with interleukin (I
Autor:
Alok Dhar, Muralidhar S. Deshpande, Jessica Gardner, Li Wu, Raisa Persidsky, Anuja Ghorpade, Kathleen Borgmann
Publikováno v:
Journal of neuroscience research. 83(7)
The pathogenesis of many neurodegenerative disorders, including human immunodeficiency virus (HIV)-1 associated dementia, is exacerbated by an imbalance between matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloprotei
Autor:
Yuri Persidsky, James Haorah, Kozo Kaibuchi, Marina Zelivyanskaya, Hiroaki Shimokawa, David Heilman, Raisa Persidsky, Tsuneya Ikezu, Gregory A. Weber
Publikováno v:
Blood. 107(12)
The blood-brain barrier (BBB) is compromised during progressive HIV-1 infection, but how this occurs is incompletely understood. We studied the integrity of tight junctions (TJs) of brain microvascular endothelial cells (BMVECs) in an in vitro BBB sy
Autor:
Robin L. Cotter, Raisa Persidsky, Y. Persidsky, Susan Swindells, Howard E. Gendelman, Anuja Ghorpade, Spring Holter, Kathleen Borgmann
Publikováno v:
Journal of neuroimmunology. 163(1-2)
Microglial and macrophage infection and immune activation underlie the pathogenesis of HIV-1-associated dementia (HAD). To assess microglial function in HAD, we isolated cells from brain tissues recovered from an HIV-1-infected patient within 4 h of
Autor:
Radhika Suryadevara, Spring Holter, Kathleen Borgmann, Raisa Persidsky, Christine Labenz-Zink, Yuri Persidsky, Howard E. Gendelman, Li Wu, Anuja Ghorpade
Publikováno v:
Glia; Oct2003, Vol. 44 Issue 1, p47, 10p