SARS-CoV-2 uses CD4 to infect T helper lymphocytes

Autor: Natalia S Brunetti, Gustavo G Davanzo, Diogo de Moraes, Allan JR Ferrari, Gabriela F Souza, Stéfanie Primon Muraro, Thiago L Knittel, Vinicius O Boldrini, Lauar B Monteiro, João Victor Virgílio-da-Silva, Gerson S Profeta, Natália S Wassano, Luana Nunes Santos, Victor C Carregari, Artur HS Dias, Flavio P Veras, Lucas A Tavares, Julia Forato, Icaro MS Castro, Lícia C Silva-Costa, André C Palma, Eli Mansour, Raisa G Ulaf, Ana F Bernardes, Thyago A Nunes, Luciana C Ribeiro, Marcus V Agrela, Maria Luiza Moretti, Lucas I Buscaratti, Fernanda Crunfli, Raissa G Ludwig, Jaqueline A Gerhardt, Natália Munhoz-Alves, Ana Maria Marques, Renata Sesti-Costa, Mariene R Amorim, Daniel A Toledo-Teixeira, Pierina Lorencini Parise, Matheus Cavalheiro Martini, Karina Bispos-dos-Santos, Camila L Simeoni, Fabiana Granja, Virgínia C Silvestrini, Eduardo B de Oliveira, Vitor M Faca, Murilo Carvalho, Bianca G Castelucci, Alexandre B Pereira, Laís D Coimbra, Marieli MG Dias, Patricia B Rodrigues, Arilson Bernardo SP Gomes, Fabricio B Pereira, Leonilda MB Santos, Louis-Marie Bloyet, Spencer Stumpf, Marjorie C Pontelli, Sean Whelan, Andrei C Sposito, Robson F Carvalho, André S Vieira, Marco AR Vinolo, André Damasio, Licio Velloso, Ana Carolina M Figueira, Luis LP da Silva, Thiago Mattar Cunha, Helder I Nakaya, Henrique Marques-Souza, Rafael E Marques, Daniel Martins-de-Souza, Munir S Skaf, Jose Luiz Proenca-Modena, Pedro MM Moraes-Vieira, Marcelo A Mori, Alessandro S Farias

Publikováno v: eLife, Vol 12 (2023)

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related c

Externí odkaz: https://doaj.org/article/99a35dd8fb984baea7fc8271d68472e7

Plasma Angiotensin II Is Increased in Critical Coronavirus Disease 2019

Autor: Rafael L. Camargo, Bruna Bombassaro, Milena Monfort-Pires, Eli Mansour, Andre C. Palma, Luciana C. Ribeiro, Raisa G. Ulaf, Ana Flavia Bernardes, Thyago A. Nunes, Marcus V. Agrela, Rachel P. Dertkigil, Sergio S. Dertkigil, Eliana P. Araujo, Wilson Nadruz, Maria Luiza Moretti, Licio A. Velloso, Andrei C. Sposito

Publikováno v: Frontiers in cardiovascular medicine. 9

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have suggested that upon viral binding, ACE2 catalytic activity could be inhibited; therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331fe5774be284f51eb3e1dccb898f70
https://pubmed.ncbi.nlm.nih.gov/36324738

Outcome of SARS-CoV-2 Infection in 121 Patients With Inborn Errors of Immunity: A Cross-sectional Study

Autor: Gisele Loth, Fernanda Casares Marcelino, Irma Cecília Douglas Paes Barreto, Carolina Sanchez Aranda, Sérgio Duarte Dortas Junior, Laire Schidlowski, Juliana Folloni Fernandes, Simone Pestana, Eli Mansour, Maria Luiza Oliva Alonso, Almerinda Rego Silva, Gustavo Soldateli, Raisa G. Ulaf, Priscila Fillipo, Olga Akiko Takano, Pérsio Roxo-Junior, Rafaela Guimarães, Janaíra Fernandes Ferreira, Cristina M. Kokron, Ekaterini Goudouris, Solange Oliveira Rodrigues Valle, Carmem Bonfim, Danielli Christinni Bichuetti-Silva, Eliana C. Toledo, Antonio Condino-Neto, Luciana Araújo Oliveira Cunha, Anete Sevciovic Grumach, Fernanda Pinto-Mariz, Regina Sumiko Watanabe Di Gesu, Natasha Rebouças Ferraroni, Maria Isabel Valdomir Nadaf, Julia Lopes Garcia, Leonardo Oliveira Mendonça, Ellen de Oliveira Dantas, Fernanda Lugão Campinhos, Flavia Anisio, Myrthes Toledo Barros, Albertina Varandas Capelo, Carolina Prando

Publikováno v: Journal of Clinical Immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Purpose: There is still scarce data on SARS-CoV-2 infection in patients with Inborn Errors of Immunity (IEI) and many questions. We aimed to describe the clinical outcome of SARS-CoV-2 infection in Brazilian IEI patients and to identify factors influ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf3aa282d5ebcf5a075aab4f86697aa
https://doi.org/10.21203/rs.3.rs-286146/v1

Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin-Kallikrein System in Severe COVID-19

Autor: Licio A. Velloso, Eli Mansour, Thyago A. Nunes, Natalia S Brunetti, Eliana P. Araújo, Rafael Ludemann Camargo, Sergio Dertkigil, Raisa G. Ulaf, Marcus V. Agrela, Andre C. Palma, Antonio Luis Eiras Falcão, Rachel P Dertkigil, Luciana C. Ribeiro, Thiago Martins Santos, Plínio Trabasso, A. F. Bernardes, Bruna Bombassaro, Milena Monfort-Pires, Maria Luiza Moretti, Alessandro S. Farias

Publikováno v: Viruses, Vol 13, Iss 309, p 309 (2021)
Viruses
Volume 13
Issue 2

Background: Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major pathological finding in autopsies explaining O2 diffusion failure and hypoxemia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a767562d1eed3fe4b326b10c689803
https://pubmed.ncbi.nlm.nih.gov/33669276

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

Autor: Carlos Alberto Oliveira de Biagi Junior, Natalia S Brunetti, Robson Francisco Carvalho, André Schwambach Vieira, Victor Corasolla Carregari, Ana Campos Codo, Eli Mansour, Maria Luiza Moretti, Raisa G. Ulaf, Lais D. Coimbra, Stéfanie Primon Muraro, Licio A. Velloso, Juliana Silveira Prodonoff, Thyago A. Nunes, Lauar de Brito Monteiro, Karina Bispo dos Santos, Alexandre Borin, Guilherme Reis-de-Oliveira, André Damasio, Andrei C. Sposito, Marcus V. Agrela, Gabriela Fabiano de Souza, Fernanda Crunfli, Daniel A. Toledo-Teixeira, Helder I. Nakaya, Gustavo Gastão Davanzo, Daniel Martins-de-Souza, Pierina Lorencini Parise, Pedro M. Moraes-Vieira, Jeffersson Leandro Jimenez Restrepo, Vinícius O. Boldrini, Rafael Elias Marques, Alessandro S. Farias, João Victor Virgilio-da-Silva, Andre C. Palma, A. F. Bernardes, Fabrício Bíscaro Pereira, Helison R. Carmo, Marcelo A. Mori, Luciana C. Ribeiro, José Luiz Proença-Módena, Pedro Henrique Vendramini, Marco Aurélio Ramirez Vinolo, M. C. Martini

Publikováno v: Cell Metabolism
Signal Transduction and Targeted Therapy
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Made available in DSpace on 2020-12-12T02:25:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2143060a61e4753e054c25c25cc99d65