Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rainer W. J. Kaiser"'
Autor:
Rainer W. J. Kaiser, Julian Allgeier, Alexander B. Philipp, Julia Mayerle, Camilla Rothe, Claudia Wallrauch, Mark op den Winkel
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Infection with Entamoeba histolytica and associated complications are relatively rare in developed countries. The overall low prevalence in the Western world as well as the possibly prolonged latency period between infection with
Externí odkaz:
https://doaj.org/article/9921ee8a36314a6fa5f51ae167785c95
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The DNA damage response (DDR) is a complex signaling network that is activated upon genotoxic stress. It determines cellular fate by either activating cell cycle arrest or initiating apoptosis and thereby ensures genomic stability. The Apoptosis Anta
Externí odkaz:
https://doaj.org/article/b418a4ac85b14c7dbc650292bcc9b186
Autor:
Hans C. Reinhardt, Tim Hucho, Thorsten Persigehl, Florian Siedek, Rainer W. J. Kaiser, Anna Schmitt, Filippo Beleggia, André Toschka, Leonard A. Lobbes, Jörg Isensee, Joachim D. Steiner, Johanna Erber
The advent of molecularly targeted therapeutic agents has opened a new era in cancer therapy. However, many tumors rely on nondruggable cancer-driving lesions. In addition, long-lasting clinical benefits from single-agent therapies rarely occur, as m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6396e06eeff0ee65f06b6cda1afa5d9
https://doi.org/10.1158/0008-5472.c.6511272.v1
https://doi.org/10.1158/0008-5472.c.6511272.v1
Autor:
Hans C. Reinhardt, Tim Hucho, Thorsten Persigehl, Florian Siedek, Rainer W. J. Kaiser, Anna Schmitt, Filippo Beleggia, André Toschka, Leonard A. Lobbes, Jörg Isensee, Joachim D. Steiner, Johanna Erber
Table S5 contains data of the GSEA analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb3fd557a38b242c30ed65658b3f6db
https://doi.org/10.1158/0008-5472.22422567
https://doi.org/10.1158/0008-5472.22422567
Autor:
Hans C. Reinhardt, Tim Hucho, Thorsten Persigehl, Florian Siedek, Rainer W. J. Kaiser, Anna Schmitt, Filippo Beleggia, André Toschka, Leonard A. Lobbes, Jörg Isensee, Joachim D. Steiner, Johanna Erber
Figure S1 shows single agent dose-response curves of 18 compounds employed in the screen. Figure S2 shows synergy scores of 23 compound combinations. Figure S3 shows the apoptotic effects of single agent inhibitors and their combinations on a panel o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06490850f1cffd0a2d8d0966d8f1fb0
https://doi.org/10.1158/0008-5472.22422588.v1
https://doi.org/10.1158/0008-5472.22422588.v1
Autor:
Hans C. Reinhardt, Tim Hucho, Thorsten Persigehl, Florian Siedek, Rainer W. J. Kaiser, Anna Schmitt, Filippo Beleggia, André Toschka, Leonard A. Lobbes, Jörg Isensee, Joachim D. Steiner, Johanna Erber
Table S6 contains all p-values related to Fig. 4C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b68873ae198a4ef243215f2c1d1077f
https://doi.org/10.1158/0008-5472.22422585.v1
https://doi.org/10.1158/0008-5472.22422585.v1
Autor:
Johanna, Erber, Joachim D, Steiner, Jörg, Isensee, Leonard A, Lobbes, André, Toschka, Filippo, Beleggia, Anna, Schmitt, Rainer W J, Kaiser, Florian, Siedek, Thorsten, Persigehl, Tim, Hucho, Hans C, Reinhardt
Publikováno v:
Cancer research. 79(19)
The advent of molecularly targeted therapeutic agents has opened a new era in cancer therapy. However, many tumors rely on nondruggable cancer-driving lesions. In addition, long-lasting clinical benefits from single-agent therapies rarely occur, as m