Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Rainer W. Friedrich"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
Fixation and staining of large tissue samples are critical for the acquisition of volumetric electron microscopic image datasets and the subsequent reconstruction of neuronal circuits. Efficient protocols exist for the staining of small samples, but
Externí odkaz:
https://doaj.org/article/3c2f703a967f4911b1e6f9145ecd866b
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
We present SBEMimage, an open-source Python-based application to operate serial block-face electron microscopy (SBEM) systems. SBEMimage is designed for complex, challenging acquisition tasks, such as large-scale volume imaging of neuronal tissue or
Externí odkaz:
https://doaj.org/article/72646fc467a748bd80932daddfd0a1db
Publikováno v:
Frontiers in Neural Circuits, Vol 6 (2012)
Dopamine (DA) is an important modulator of synaptic transmission and plasticity that is causally involved in fundamental brain functions and dysfunctions. We examined the dopaminergic modulation of synaptic transmission and sensory responses in telen
Externí odkaz:
https://doaj.org/article/afad9dc1736d4d4aaf0864ca1b9f745c
Autor:
Chie Satou, Rachael L Neve, Hassana K Oyibo, Pawel Zmarz, Kuo-Hua Huang, Estelle Arn Bouldoires, Takuma Mori, Shin-ichi Higashijima, Georg B Keller, Rainer W Friedrich
Publikováno v:
eLife, Vol 11 (2022)
The zebrafish is an important model in systems neuroscience but viral tools to dissect the structure and function of neuronal circuitry are not established. We developed methods for efficient gene transfer and retrograde tracing in adult and larval z
Externí odkaz:
https://doaj.org/article/953084a35d814ae0a44b105f74d5fa17
Autor:
Philipp Berens, Jeremy Freeman, Thomas Deneux, Nikolay Chenkov, Thomas McColgan, Artur Speiser, Jakob H Macke, Srinivas C Turaga, Patrick Mineault, Peter Rupprecht, Stephan Gerhard, Rainer W Friedrich, Johannes Friedrich, Liam Paninski, Marius Pachitariu, Kenneth D Harris, Ben Bolte, Timothy A Machado, Dario Ringach, Jasmine Stone, Luke E Rogerson, Nicolas J Sofroniew, Jacob Reimer, Emmanouil Froudarakis, Thomas Euler, Miroslav Román Rosón, Lucas Theis, Andreas S Tolias, Matthias Bethge
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 5, p e1006157 (2018)
In recent years, two-photon calcium imaging has become a standard tool to probe the function of neural circuits and to study computations in neuronal populations. However, the acquired signal is only an indirect measurement of neural activity due to
Externí odkaz:
https://doaj.org/article/358eea9214b64f3889ddd1a4b6f1cd9d
Autor:
Chie Satou, Rachael L Neve, Hassana K Oyibo, Pawel Zmarz, Kuo-Hua Huang, Estelle Arn Bouldoires, Takuma Mori, Shin-ichi Higashijima, Georg B Keller, Rainer W Friedrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b44bb3d9d39664d4ba4eec57ba8a40
https://doi.org/10.7554/elife.77153.sa2
https://doi.org/10.7554/elife.77153.sa2
Autor:
Rainer W. Friedrich, Adrian A. Wanner
Publikováno v:
Nature neuroscience
Neuronal computations underlying higher brain functions depend on synaptic interactions among specific neurons. A mechanistic understanding of such computations requires wiring diagrams of neuronal networks. In this study, we examined how the olfacto
Autor:
Yang Dan, Peter Rupprecht, Fritjof Helmchen, Kazuo Kitamura, Antonin Blot, Adrian Hoffmann, Stefano Carta, Alex C. Kwan, Sonja B. Hofer, Rainer W. Friedrich, Mayumi Echizen
Publikováno v:
Nature Neuroscience, vol 24, iss 9
Nature neuroscience
Nature neuroscience
Inference of action potentials (‘spikes’) from neuronal calcium signals is complicated by the scarcity of simultaneous measurements of action potentials and calcium signals (‘ground truth’). In this study, we compiled a large, diverse ground
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac33f74dd5b700ad0ee54b7eabfcc6f1
https://escholarship.org/uc/item/9sw746d5
https://escholarship.org/uc/item/9sw746d5
Autor:
Rainer W. Friedrich, Chie Satou
Publikováno v:
Neuron
Summary Inhibitory neurons orchestrate the activity of excitatory neurons and play key roles in circuit function. Although individual interneurons have been studied extensively, little is known about their properties at the population level. Using ra
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
The zebrafish has various advantages as a model organism to analyze the structure and function of neural circuits but efficient viruses or other tools for fast gene transfer are lacking. We show that transgenes can be introduced directly into the adu
Externí odkaz:
https://doaj.org/article/45153dbe9a5c44c1bac35920167e608a