Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Rainer Stahl"'
Autor:
Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, Eicke Latz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Leucine-rich repeat (LRR) domains are commonly present in immune regulatory proteins. Here the authors show that LRR exonic modularity and alternative splicing of an LRR-containing protein, NLRP3, modulate the ratio of functional/afunctional NLRP3 is
Externí odkaz:
https://doaj.org/article/e8556fbf0c984427a366f6b71e4114ec
Autor:
Rainer Stahl
Publikováno v:
Религия, церковь, общество, Vol 7, Pp 44-67 (2018)
The text «Martin Luther inspires and stimulates contradictions» continues the second part of the artcile based on the report read 11. April 2017 in Tscheboskary and published in the previous volume of the almanac. The author raises such questions a
Externí odkaz:
https://doaj.org/article/11665525aa594565a0f6eca5a64bea87
Autor:
Rainer Stahl
Publikováno v:
Религия, церковь, общество, Vol 3, Pp 42-68 (2014)
The article describes specifics of the Lutheran identity, mainly relying on the vision of Luther. The author emphasizes conservatism and orthodoxy of the Lutheran Church, drawing parallels between the preaching of Luther and the content of Orthodox i
Externí odkaz:
https://doaj.org/article/f9b836e946d44d079b138f138a264b24
Autor:
Tomasz Próchnicki, Matilde B. Vasconcelos, Kim S. Robinson, Matthew S. J. Mangan, Dennis De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G. Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A. Kufer, Florian I. Schmidt, Franklin L. Zhong, Eicke Latz
Publikováno v:
Nature immunology 24(4), 595-603 (2023). doi:10.1038/s41590-023-01451-y
Upon detecting pathogens or cell stress, several NOD-like receptors (NLRs) form inflammasome complexes with the adapter ASC and caspase-1, inducing gasdermin D (GSDMD)-dependent cell death and maturation and release of IL-1β and IL-18. The triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951cef744dde927be85ce561d1cb4398
Autor:
Gerald Seifert, Florian Hoss, Stefan Canzar, Juan F. Rodriguez-Alcazar, Matthias Geyer, Francisca Rojas Ringeling, Hal M. Hoffman, Rainer Stahl, Christopher D. Putnam, James L. Mueller, Lori Broderick, Eicke Latz, Richard D. Kolodner, Rebecca Brinkschulte
Publikováno v:
Nature Communications 10(1), 3238 (2019). doi:10.1038/s41467-019-11076-1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we report strict exonic modularity of LRR domains of several human gene families, which is a precondition for alternative splic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7956af9e03ff5838d792045b0e2b2f9f
Autor:
Seth L. Masters, Larisa I. Labzin, Dieter Lütjohann, Rainer Stahl, Joachim L. Schultze, Dominic De Nardo, Wolfgang Krebs, Eicke Latz, Susanne Schmidt, Kathrin Klee, Marc Beyer
Publikováno v:
The journal of immunology 195(9), 4446-4455 (2015). doi:10.4049/jimmunol.1500204
Cytokines and IFNs downstream of innate immune pathways are critical for mounting an appropriate immune response to microbial infection. However, the expression of these inflammatory mediators is tightly regulated, as uncontrolled production can resu
Autor:
Felix Meissner, Melanie M. Brinkmann, Anette Christ, Kensuke Miyake, Damien Bertheloot, Ann Marshak-Rothstein, Susanne V. Schmidt, Albert Haas, Nir Hacohen, Rainer Stahl, Nicki Watson, Karin Pelka, Elisa Reimer, Kshiti Phulphagar, Eicke Latz
Publikováno v:
Immunity 48(5), 911-922.e7 (2018). doi:10.1016/j.immuni.2018.04.011
Unc-93 homolog B1 (UNC93B1) is a key regulator of nucleic acid (NA)-sensing Toll-like receptors (TLRs). Loss of NA-sensing TLR responses in UNC93B1-deficient patients facilitates Herpes simplex virus type 1 (HSV-1) encephalitis. UNC93B1 is thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56435af85e42171a78bb76727c353ed
Autor:
Rebecca Brinkschulte, Carl-Christian Kolbe, Eicke Latz, Felix Meissner, Gabor Horvath, Matthias Geyer, Bernardo S. Franklin, Olivia van Ray, Andrea Stutz, Rainer Stahl
Publikováno v:
The Journal of Experimental Medicine
Journal of experimental medicine 214(6), 1725-1736 (2017). doi:10.1084/jem.20160933
Journal of Experimental Medicine
Journal of experimental medicine 214(6), 1725-1736 (2017). doi:10.1084/jem.20160933
Journal of Experimental Medicine
NLRP3 is an innate immune receptor that needs to be tightly regulated to prevent overshooting immune responses. Stutz et al. demonstrate that NLRP3 is phosphorylated as a safeguard against accidental activation, and that dephosphorylation involving P