Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Rainer Riedl"'
Autor:
Stefano Bagatella, Neda Haghayegh Jahromi, Camille Monney, Margherita Polidori, Flavio Max Gall, Emma Marchionatti, Fabienne Serra, Rainer Riedl, Britta Engelhardt, Anna Oevermann
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Listeria monocytogenes (Lm) is a bacterial pathogen of major concern for humans and ruminants due to its neuroinvasive potential and its ability to cause deadly encephalitis (neurolisteriosis). On one hand, polymorphonuclear neutr
Externí odkaz:
https://doaj.org/article/e6aa289764974071912354939d60408a
Autor:
Fabienne Arn, David Frasson, Ivana Kroslakova, Fabio Rezzonico, Joel F. Pothier, Rainer Riedl, Martin Sievers
Publikováno v:
CHIMIA, Vol 74, Iss 5, Pp 382-391 (2020)
Actinomycetes strains isolated from different habitats in Switzerland were investigated for production of antibacterial and antitumoral compounds. Based on partial 16S rRNA gene sequences, the isolated strains were identified to genus level. Streptom
Externí odkaz:
https://doaj.org/article/db6b8abbed524e9d81f5d82e50295f4e
Autor:
Stefan Höck, Rainer Riedl
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract We present the development of CyBy 2 , a versatile framework for chemical data management written in purely functional style in Scala, a modern multi-paradigm programming language. Together with the core libraries we provide a fully function
Externí odkaz:
https://doaj.org/article/a02e3a722bb940f1aeff3db7ed8bdbcc
Autor:
Neeta Shrestha, Flavio Max Gall, Cyrille Mathieu, Melanie Michaela Hierweger, Melanie Brügger, Marco P. Alves, Jonathan Vesin, Damiano Banfi, David Kalbermatter, Branka Horvat, Marc Chambon, Gerardo Turcatti, Dimitrios Fotiadis, Rainer Riedl, Philippe Plattet
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance. Each year a huge
Externí odkaz:
https://doaj.org/article/7716b1d33ef34c06b47fd4ee9b13b0ad
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12085 (2022)
SUMOylation is a reversible post–translational modification (PTM) involving covalent attachment of small ubiquitin-related modifier (SUMO) proteins to substrate proteins. Dysregulation of SUMOylation and deSUMOylation results in cellular malfunctio
Externí odkaz:
https://doaj.org/article/836ed9f8bfe34257895a3da11b192d21
Autor:
David Kalbermatter, Neeta Shrestha, Flavio M. Gall, Marianne Wyss, Rainer Riedl, Philippe Plattet, Dimitrios Fotiadis
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100021- (2020)
Measles virus (MeV) and canine distemper virus (CDV), two members of the Morbillivirus genus, are still causing important global diseases of humans and animals, respectively. To enter target cells, morbilliviruses rely on an envelope-anchored machine
Externí odkaz:
https://doaj.org/article/573cb23fb8ff426cbfe1a9637681e4b8
Autor:
Neeta Shrestha, Flavio M. Gall, Jonathan Vesin, Marc Chambon, Gerardo Turcatti, Dimitrios Fotiadis, Rainer Riedl, Philippe Plattet
Publikováno v:
Viruses, Vol 13, Iss 1, p 128 (2021)
Canine distemper virus (CDV), a close relative of the human pathogen measles virus (MeV), is an enveloped, negative sense RNA virus that belongs to the genus Morbillivirus and causes severe diseases in dogs and other carnivores. Although the vaccinat
Externí odkaz:
https://doaj.org/article/270bbfc54ac149ec9707568fef0c3b97
Autor:
Thomas Fischer, Rainer Riedl
Publikováno v:
Molecules, Vol 24, Iss 12, p 2265 (2019)
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis. Modulation of the target class with small molecule dr
Externí odkaz:
https://doaj.org/article/6bc176b58d714472afd56d88b189c6fd
Autor:
Thomas Fischer, Symeon M. Koulas, Anastasia S. Tsagkarakou, Efthimios Kyriakis, George A. Stravodimos, Vassiliki T. Skamnaki, Panagiota G.V. Liggri, Spyros E. Zographos, Rainer Riedl, Demetres D. Leonidas
Publikováno v:
Molecules, Vol 24, Iss 7, p 1322 (2019)
Structure-based design and synthesis of two biphenyl-N-acyl-β-d-glucopyranosylamine derivatives as well as their assessment as inhibitors of human liver glycogen phosphorylase (hlGPa, a pharmaceutical target for type 2 diabetes) is presented. X-ray
Externí odkaz:
https://doaj.org/article/b9197cf13d4b429d8c5405c18af6b576
Autor:
Thomas Fischer, Rainer Riedl
Publikováno v:
Molecules, Vol 22, Iss 9, p 1548 (2017)
Matrix metalloproteinase 7 (MMP-7) is a member of the MMP superfamily and is able to degrade extracellular matrix proteins such as casein, gelatin, fibronectin and proteoglycan. MMP-7 is a validated target for the development of small molecule drugs
Externí odkaz:
https://doaj.org/article/0dadc9cb975e4eebb7ca976bcae6dbe0