Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rainer Quaas"'
Autor:
Felista L. Tansi, Wisdom O. Maduabuchi, Melanie Hirsch, Paul Southern, Simon Hattersley, Rainer Quaas, Ulf Teichgräber, Quentin A. Pankhurst, Ingrid Hilger
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 743-754 (2021)
Objective Deep-tissue localization of thermal doses is a long-standing challenge in magnetic field hyperthermia (MFH), and remains a limitation of the clinical application of MFH to date. Here, we show that pulse sequencing of MFH leads to a more per
Externí odkaz:
https://doaj.org/article/360575b57d59400c930b4c1f5a733fdf
Autor:
Mohammad Dabaghi, Seyed Mohammad Mahdi Rasa, Emilio Cirri, Alessandro Ori, Francesco Neri, Rainer Quaas, Ingrid Hilger
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1625 (2021)
In this study we looked for the main protein pathway regulators which were responsible for the therapeutic impact on colon cancers when combining magnetic hyperthermia with the chemotherapeutic agent 5-fluorouracil (5FU). To this end, chitosan-coated
Externí odkaz:
https://doaj.org/article/536977fbce314dfebcddc733341a83d5
Autor:
Felista L. Tansi, Filipp Fröbel, Wisdom O. Maduabuchi, Frank Steiniger, Martin Westermann, Rainer Quaas, Ulf K. Teichgräber, Ingrid Hilger
Publikováno v:
Nanomaterials, Vol 11, Iss 2, p 438 (2021)
Magnetic hyperthermia can cause localized thermal eradication of several solid cancers. However, a localized and homogenous deposition of high concentrations of magnetic nanomaterials into the tumor stroma and tumor cells is mostly required. Poorly r
Externí odkaz:
https://doaj.org/article/dc7139daeb054ca39fdeb908ee0beb75
Autor:
Felista L. Tansi, Filipp Fröbel, Wisdom O. Maduabuchi, Frank Steiniger, Martin Westermann, Rainer Quaas, Ulf K. Teichgräber, Ingrid Hilger
Publikováno v:
Nanomaterials
Nanomaterials, Vol 11, Iss 438, p 438 (2021)
Nanomaterials, Vol 11, Iss 438, p 438 (2021)
Magnetic hyperthermia can cause localized thermal eradication of several solid cancers. However, a localized and homogenous deposition of high concentrations of magnetic nanomaterials into the tumor stroma and tumor cells is mostly required. Poorly r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a203e203857bf7a6ebf10454b4153d0c
https://pubmed.ncbi.nlm.nih.gov/33572222
https://pubmed.ncbi.nlm.nih.gov/33572222
Publikováno v:
Gene. 98:83-88
We constructed a semisynthetic gene encoding a DNA-adenine-methyltransferase (Dam) that codes for the same amino acid sequence as the wild type (wt) Escherichia coli dam gene. Since for unknown reasons the entire wt sequence, from the start codon to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3f07126b4aebaf4656f620617b466a
https://doi.org/10.1016/0378-1119(91)90107-m
https://doi.org/10.1016/0378-1119(91)90107-m
Publikováno v:
Biochemistry. 29:3053-3061
It is our aim to elucidate molecular aspects of the mechanism of protein folding. We use ribonuclease T1 as a model protein, because it is a small single-domain protein with a well-defined secondary and tertiary structure, which is stable in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38901c12678a079e665b66e3590c4fc1
https://doi.org/10.1021/bi00464a023
https://doi.org/10.1021/bi00464a023
Publikováno v:
European journal of biochemistry. 197(3)
Uniformly 15N-enriched ribonuclease T1 (RNase T1) was obtained from Escherichia coli by recombinant techniques. Heteronuclear 1H, 15N-shift correlation spectra were recorded utilizing proton detection. Direct 1H, 15N connectivities were established a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff5f46159d47aa2c699d1704ded1ce2
https://pubmed.ncbi.nlm.nih.gov/1903106
https://pubmed.ncbi.nlm.nih.gov/1903106
Autor:
Rainer Quaas, Yannis Georgalis, Wolfram Saenger, Ulrich Hahn, A. Zouni, Hans-Peter Grunert, Marc Beineke
Publikováno v:
European journal of biochemistry. 197(1)
Using an Escherichia coli overproducing strain secreting Aspergillus oryzae RNase T1, we have constructed and characterized mutants where amino acid residues in the catalytic center have been substituted. The mutants are His40----Thr, Glu58----Asp, G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4606053b27aa868e056568bf2989f7
https://pubmed.ncbi.nlm.nih.gov/1901790
https://pubmed.ncbi.nlm.nih.gov/1901790
Autor:
Ulrich Hahn, Hans Juergen Hinz, Rainer Quaas, Michael Renner, Franz X. Schmid, Thomas Kiefhaber
Publikováno v:
Biochemistry. 29(36)
The conformational stability of recombinant Lys25-ribonuclease T1 has been determined by differential scanning microcalorimetry (DSC), UV-monitored thermal denaturation measurements, and isothermal Gdn.HCl unfolding studies. Although rather different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e562b233d16e8c3a8e68bc71a1a5c8eb
https://pubmed.ncbi.nlm.nih.gov/2123715
https://pubmed.ncbi.nlm.nih.gov/2123715
Publikováno v:
Biochemistry. 29(12)
The slow refolding of ribonuclease T1 was investigated by different probes. Structural intermediates with secondary structure are formed early during refolding, as indicated by the rapid regain of a native-like circular dichroism spectrum in the amid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a19a9b4f7e0bb2cbd1ee850d7d6ee73
https://pubmed.ncbi.nlm.nih.gov/2110824
https://pubmed.ncbi.nlm.nih.gov/2110824