Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Rainer M. Bohle"'
Autor:
Yuguang Fu, Marianne Wedde, Sigrun Smola, Djin-Ye Oh, Thorsten Pfuhl, Jürgen Rissland, Michael Zemlin, Fidelis A. Flockerzi, Rainer M. Bohle, Andrea Thürmer, Susanne Duwe, Barbara Biere, Janine Reiche, Brunhilde Schweiger, Christin Mache, Thorsten Wolff, Georg Herrler, Ralf Dürrwald
Publikováno v:
International Journal of Medical Microbiology, Vol 314, Iss , Pp 151598- (2024)
Respiratory viral infections may have different impacts ranging from infection without symptoms to severe disease or even death though the reasons are not well characterized.A patient (age group 5–15 years) displaying symptoms of hemolytic uremic s
Externí odkaz:
https://doaj.org/article/f28aedf87c504504a2ae355ef5707073
Autor:
Vivien Becker, Xu Yuan, Anne S. Boewe, Emmanuel Ampofo, Elke Ebert, Johannes Hohneck, Rainer M. Bohle, Eckart Meese, Yingjun Zhao, Michael D. Menger, Matthias W. Laschke, Yuan Gu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 421-436 (2023)
The tumor microenvironment stimulates the angiogenic activity of endothelial cells (ECs) to facilitate tumor vascularization, growth, and metastasis. The involvement of microRNA-186-5p (miR-186) in regulating the aberrant activity of tumor-associated
Externí odkaz:
https://doaj.org/article/cd58792a924c4f558ad1c42dfc301f1a
Autor:
Eleni Kolokotroni, Daniel Abler, Alokendra Ghosh, Eleftheria Tzamali, James Grogan, Eleni Georgiadi, Philippe Büchler, Ravi Radhakrishnan, Helen Byrne, Vangelis Sakkalis, Katerina Nikiforaki, Ioannis Karatzanis, Nigel J. B. McFarlane, Djibril Kaba, Feng Dong, Rainer M. Bohle, Eckart Meese, Norbert Graf, Georgios Stamatakos
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 5, p 475 (2024)
The massive amount of human biological, imaging, and clinical data produced by multiple and diverse sources necessitates integrative modeling approaches able to summarize all this information into answers to specific clinical questions. In this paper
Externí odkaz:
https://doaj.org/article/672a470652a64f7583dca57cffde506c
Autor:
Moritz Knebel, Sandrina Körner, Jan Philipp Kühn, Silke Wemmert, Lukas Brust, Sigrun Smola, Mathias Wagner, Rainer M. Bohle, Luc G. T. Morris, Abhinav Pandey, Bernhard Schick, Maximilian Linxweiler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDue to the expanding role of immune checkpoint inhibition in the treatment of head and neck squamous cell carcinoma, understanding immunological processes in the tumor microevironment (TME) has strong translational importance. Though analyt
Externí odkaz:
https://doaj.org/article/30b9a2010e504d77a57499bbbac3ac7c
Autor:
Mariz Kasoha, Anna K. Steinbach, Rainer M. Bohle, Barbara Linxweiler, Bashar Haj Hamoud, Merle Doerk, Meletios P. Nigdelis, Lisa Stotz, Julia S. M. Zimmermann, Erich-Franz Solomayer, Askin C. Kaya, Julia C. Radosa
Publikováno v:
Cancers, Vol 16, Iss 2, p 419 (2024)
Purpose: To investigate the role of Dkk1 as a predictor of response to NACT in BC patients. Methods: This retrospective monocentric study included 145 women who had undergone NACT followed by breast surgery. Dkk1 protein expression was assessed using
Externí odkaz:
https://doaj.org/article/5af5840d983245e493456af7a0a3e4ce
Autor:
Jan Niklas Mink, Oybek Khalmurzaev, Alexey Pryalukhin, Carol Immanuel Geppert, Stefan Lohse, Kristof Bende, João Lobo, Rui Henrique, Hagen Loertzer, Joachim Steffens, Carmen Jerónimo, Heiko Wunderlich, Julia Heinzelbecker, Rainer M. Bohle, Michael Stöckle, Vsevolod Matveev, Arndt Hartmann, Kerstin Junker
Publikováno v:
Cancers, Vol 15, Iss 19, p 4748 (2023)
Background: Advanced penile carcinoma is characterized by poor prognosis. Most data on prognostic factors are based on small study cohorts, and even meta-analyses are limited in patient numbers. Therefore, there is still a lack of evidence for clinic
Externí odkaz:
https://doaj.org/article/6bab97bae6984cbab3b2ce77b0e80661
Autor:
Julia C. Radosa, Mariz Kasoha, Anne-Christine Schilz, Zoltan F. Takacs, Askin Kaya, Marc P. Radosa, Barbara Linxweiler, Maximilian Linxweiler, Rainer M. Bohle, Mathias Wagner, Gudrun Wagenpfeil, Erich-Franz Solomayer, Julia S. M. Zimmermann
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
With approximately 220,000 newly diagnosed cases per year, ovarian cancer is among the most frequently occurring cancers among women and the second leading cause of death from gynecological malignancies worldwide. About 70% of these cancers are diagn
Externí odkaz:
https://doaj.org/article/90242dc85a1541309d6808009daaeb9c
Autor:
Yuan Gu, Gianni Pais, Vivien Becker, Christina Körbel, Emmanuel Ampofo, Elke Ebert, Johannes Hohneck, Nicole Ludwig, Eckart Meese, Rainer M. Bohle, Yingjun Zhao, Michael D. Menger, Matthias W. Laschke
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 849-864 (2021)
MicroRNAs (miRNAs) expressed in endothelial cells (ECs) are powerful regulators of angiogenesis, which is essential for tumor growth and metastasis. Here, we demonstrated that miR-22 is preferentially and highly expressed in ECs, while its endothelia
Externí odkaz:
https://doaj.org/article/1a3c19b0c39c404d9df97c3de76ab24f
Autor:
Julia C. Radosa, Mariz Kasoha, Merle Doerk, Annika Cullmann, Askin C. Kaya, Maximilian Linxweiler, Marc P. Radosa, Zoltan Takacs, Andrea Tirincsi, Sven Lang, Martin Jung, Julian Puppe, Barbara Linxweiler, Mathias Wagner, Rainer M. Bohle, Erich-Franz Solomayer, Julia S. M. Zimmermann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9576 (2023)
In the absence of targeted treatment options, neoadjuvant chemotherapy (NACT) is applied widely for triple-negative breast cancer (TNBC). Response to NACT is an important parameter predictive of oncological outcomes (progression-free and overall surv
Externí odkaz:
https://doaj.org/article/3ce0c442749c47a981ba4dceccbc1c55
Autor:
Elena Pfeuffer-Jovic, Jan Heyckendorf, Udo Reischl, Rainer M. Bohle, Thorsten Bley, Andreas Buck, Heinrike Wilkens, Hans-Joachim Schäfers, Heinz-Jakob Langen, Matthias Held
Publikováno v:
International Journal of Infectious Diseases, Vol 104, Iss , Pp 178-180 (2021)
A 57-year-old Caucasian woman suffered from dyspnea on exertion. One year following a supposed pulmonary embolism event, a chronic thromboembolic vasculopathy was diagnosed and a pulmonary thromboendarterectomy was performed. However, a granulomatous
Externí odkaz:
https://doaj.org/article/a26b754f52be4675a52c1e304b15c2fc